iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105010

Ensembl Protein ID

ENSRNOP00000026986.3

UniProt Accession

D4A454; D4A454_RAT

Genbank Protein ID

ENSRNOP00000026986

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AABR07044121

Gene Name

RGD1306091; Map3k21; Mlk4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000019931.4	ENSRNOT00000026986.4	ENSRNOP00000026986.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-13	49.5	30	85

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvkelegkrGlfPenFvek 61
            +lydyea  +deL+lk+G  v+v+      + degW+ g  + + + G+fP+ +v+ 
   Q: 30   AALYDYEARGEDELSLKRGQLVEVLsqdAAVSGDEGWWAG--QVQRRLGIFPASYVAP 85
           69***********************54444578*******..7************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MALPVAEGTA GTSLSPVRDD SGSSSSGMWA ALYDYEARGE DELSLKRGQL VEVLSQDAAV 60
SGDEGWWAGQ VQRRLGIFPA SYVAPCSSVS PPSPPPPRPC SPVHVDFERL ELKELIGAGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGC CTGTAGCCGA GGGCACGGCT GGCACCTCGC TGTCCCCGGT CCGGGACGAC 60
TCGGGGAGCT CCTCCTCCGG GATGTGGGCC GCGCTTTATG ATTACGAAGC GCGCGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0007257--P:activation of JUN kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005356	Anolis carolinensis	65.08	0.00e+00	902.00
IUUC-Bta-012631	Bos taurus	62.46	0.00e+00	915.00
IUUC-Cja-019307	Callithrix jacchus	65.58	0.00e+00	1005.00
IUUC-Cfa-020962	Canis familiaris	65.50	0.00e+00	946.00
IUUC-Cpo-021521	Cavia porcellus	81.93	0.00e+00	884.00
IUUC-Csa-023781	Chlorocebus sabaeus	66.90	0.00e+00	1005.00
IUUC-Dre-027645	Danio rerio	65.96	0.00e+00	822.00
IUUC-Gmo-039264	Gadus morhua	62.75	0.00e+00	787.00
IUUC-Gga-040976	Gallus gallus	68.49	0.00e+00	959.00
IUUC-Ggo-044536	Gorilla gorilla	68.64	0.00e+00	1073.00
IUUC-Hsa-045686	Homo sapiens	68.11	0.00e+00	999.00
IUUC-Mcc-055881	Macaca mulatta	66.16	0.00e+00	977.00
IUUC-Mdo-062770	Monodelphis domestica	77.28	0.00e+00	975.00
IUUC-Mmu-063237	Mus musculus	88.62	0.00e+00	1337.00
IUUC-Ont-071825	Oreochromis niloticus	63.32	0.00e+00	813.00
IUUC-Ocu-074362	Oryctolagus cuniculus	65.94	0.00e+00	933.00
IUUC-Oga-087967	Otolemur garnettii	68.29	0.00e+00	1032.00
IUUC-Pfo-096763	Poecilia formosa	69.41	0.00e+00	808.00
IUUC-Ppe-101625	Prunus persica	33.63	9.00e-24	105.00
IUUC-Ssc-115831	Sus scrofa	76.66	0.00e+00	907.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence