iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059600

Ensembl Protein ID

ENSMGAP00000016039.2

UniProt Accession

G1NQF3; G1NQF3_MELGA

Protein Name

Uncharacterized protein

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000015126.2	ENSMGAT00000017008.2	ENSMGAP00000016039.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	2.10e-06	27.4	99	136

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l++lv+ G+d+e a++aL ++ + ++eaA+ey+ 
   Q: 99   NRQMLQELVNAGCDQEMAVRALKQTgSRSIEAALEYIS 136
           669*********************************86 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KSSGQGLPVG PGSETSLDPK ILVGKDATRQ 60
QQMRQTAKFG PYQKALREIR YSLLPFANES SNTATVEVNR QMLQELVNAG CDQEMAVRAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCAA AGACTTTTCC TGCTACGACA TATTCTGGAA ACAGCAGACA AAGGTTACAA 60
GAGATTCGAG AAGGTTTAAA GCAGCCATCC AAATCTTCAG GTCAGGGACT GCCGGTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00433--Pkinase_C

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620--P:regulation of organ growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	76.30	0.00e+00	1765.00
IUUC-Apl-003521	Anas platyrhynchos	94.76	0.00e+00	1747.00
IUUC-Aca-004995	Anolis carolinensis	81.99	0.00e+00	1854.00
IUUC-Ame-011481	Astyanax mexicanus	63.60	0.00e+00	1343.00
IUUC-Bta-012618	Bos taurus	81.05	0.00e+00	981.00
IUUC-Cja-019430	Callithrix jacchus	73.92	0.00e+00	1632.00
IUUC-Cfa-020687	Canis familiaris	75.88	0.00e+00	1711.00
IUUC-Cpo-021985	Cavia porcellus	81.44	0.00e+00	1057.00
IUUC-Csa-023534	Chlorocebus sabaeus	90.68	0.00e+00	951.00
IUUC-Cho-024363	Choloepus hoffmanni	71.91	0.00e+00	663.00
IUUC-Dre-027538	Danio rerio	63.74	0.00e+00	1372.00
IUUC-Dno-029126	Dasypus novemcinctus	78.51	0.00e+00	1805.00
IUUC-Dor-030172	Dipodomys ordii	71.46	0.00e+00	1415.00
IUUC-Eca-033868	Equus caballus	76.68	0.00e+00	1709.00
IUUC-Eeu-034881	Erinaceus europaeus	60.25	0.00e+00	1241.00
IUUC-Fca-036203	Felis catus	71.84	0.00e+00	1576.00
IUUC-Fal-036668	Ficedula albicollis	95.56	0.00e+00	2200.00
IUUC-Gmo-039195	Gadus morhua	85.51	0.00e+00	794.00
IUUC-Gac-041789	Gasterosteus aculeatus	61.12	0.00e+00	1224.00
IUUC-Ggo-044904	Gorilla gorilla	71.81	0.00e+00	1590.00
IUUC-Hsa-046254	Homo sapiens	74.12	0.00e+00	1604.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	72.93	0.00e+00	1424.00
IUUC-Lch-050079	Latimeria chalumnae	74.47	0.00e+00	1695.00
IUUC-Loc-052265	Lepisosteus oculatus	68.42	0.00e+00	950.00
IUUC-Laf-053806	Loxodonta africana	75.31	0.00e+00	1734.00
IUUC-Mcc-055253	Macaca mulatta	74.73	0.00e+00	1625.00
IUUC-Meu-056509	Macropus eugenii	84.84	0.00e+00	823.00
IUUC-Mmr-061586	Microcebus murinus	74.00	0.00e+00	1564.00
IUUC-Mdo-062126	Monodelphis domestica	83.16	0.00e+00	1842.00
IUUC-Mmu-063164	Mus musculus	69.60	0.00e+00	1479.00
IUUC-Mpu-065992	Mustela putorius furo	76.30	0.00e+00	1761.00
IUUC-Mlu-067728	Myotis lucifugus	69.49	0.00e+00	1504.00
IUUC-Nle-069546	Nomascus leucogenys	74.47	0.00e+00	1608.00
IUUC-Opr-070872	Ochotona princeps	70.88	0.00e+00	1531.00
IUUC-Ont-072296	Oreochromis niloticus	87.42	0.00e+00	934.00
IUUC-Ocu-074068	Oryctolagus cuniculus	72.04	0.00e+00	1570.00
IUUC-Ola-086756	Oryzias latipes	83.79	0.00e+00	922.00
IUUC-Oga-089066	Otolemur garnettii	74.38	0.00e+00	1659.00
IUUC-Oar-090416	Ovis aries	77.92	0.00e+00	983.00
IUUC-Ptr-091247	Pan troglodytes	74.65	0.00e+00	1635.00
IUUC-Pan-092438	Papio anubis	74.65	0.00e+00	1623.00
IUUC-Psi-093920	Pelodiscus sinensis	89.89	0.00e+00	2085.00
IUUC-Pfo-096334	Poecilia formosa	84.02	0.00e+00	901.00
IUUC-Pab-098452	Pongo abelii	73.99	0.00e+00	1619.00
IUUC-Pca-101081	Procavia capensis	70.05	0.00e+00	1587.00
IUUC-Rno-105102	Rattus norvegicus	69.81	0.00e+00	1459.00
IUUC-Sha-106917	Sarcophilus harrisii	83.33	0.00e+00	1873.00
IUUC-Sar-113711	Sorex araneus	70.03	0.00e+00	1421.00
IUUC-Tgu-116553	Taeniopygia guttata	92.00	0.00e+00	2112.00
IUUC-Tru-118069	Takifugu rubripes	86.94	0.00e+00	919.00
IUUC-Tni-120617	Tetraodon nigroviridis	82.31	0.00e+00	904.00
IUUC-Ttr-129256	Tursiops truncatus	76.98	0.00e+00	1033.00
IUUC-Xtr-132593	Xenopus tropicalis	76.17	0.00e+00	1716.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence