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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046857
Ensembl Protein ID ENSP00000360065.3
UniProt Accession Q5VTH9; A8K9W5; B5MDT3; H7BY80; Q5VTI0; Q8N5G5; Q9H5R9; Q9UF44; WDR78_HUMAN
Genbank Protein ID BAB15551.1; BAF85519.1; CAH71842.1; CAH71842.1; CAH71842.1; CAH72704.1; CAH72704.1; CAH72705.1; CAH72705.1; CAH72705.1; CAI18871.1; CAI18871.1; CAI18872.1; CAI18872.1; CAI18872.1; AAH32406.2; CAB63744.3
Protein Name WD repeat-containing protein 78
Genbank Nucleotide ID AK026782; AK292830; AL354978; AL139216; AL592161; AL592161; AL139216; AL592161; AL139216; AL354978; AL139216; AL592161; AL139216; AL354978; AL592161; BC032406; AL133617
Gene Name WDR78
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000152763.16 ENST00000371026.7 ENSP00000360065.3
ENSG00000152763.16 ENST00000491297.6 ENSP00000435836.1
ENSG00000152763.16 ENST00000464352.6 ENSP00000433682.1
ENSG00000152763.16 ENST00000371023.7 ENSP00000360062.3
ENSG00000152763.16 ENST00000531552.1 ENSP00000433037.1
ENSG00000152763.16 ENST00000469450.1 ENSP00000432979.1
ENSG00000152763.16 ENST00000531980.5 ENSP00000436463.1
ENSG00000152763.16 ENST00000371022.3 ENSP00000360061.3
ENSG00000152763.16 ENST00000532629.1 ENSP00000432461.1
ENSG00000152763.16 ENST00000488333.2 ENSP00000434351.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmicroRNATRANSFACTargetScan
RepTarmiRcodeRAID2
Protein-protein Interaction
IID
Disease-associated Variation
GWASdbGWAS Central
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.30e-11 46.0 538 569
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 5    svtclaf....sdtllvsGsdDgtikvWDlrtg 33
           +vt+++f    + +ll++G ++gti ++++r++
   Q: 538  GVTAVDFsigaP-NLLAVGYHNGTIAIYNVRSN 569
           5999***99876.9***************9986 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MTPGKHSGAS ARAANGGAWG YRDFRGGQKK GWCTTPQLVA TMPVSPAGSH KQQNFGLNNA 60
TQPKKSISFF ATMKATSVKG YTGANQSRMA VSKTVLIPPE LKTVEKPNPN IKTTQVFDIN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046857|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCGTGCCGC CAGCCAACCG CGCGGCCGCT TGTTGAGCCA GGGCTCCACC GTCGCCATGA 60
CGCCCGGCAA ACATTCCGGA GCCTCGGCCC GAGCCGCTAA CGGAGGAGCT TGGGGGTACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046857|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0002244--P:hematopoietic progenitor cell differentiation
KEGG hsa:79819
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002359 Ailuropoda melanoleuca 80.30 0.00e+00 1260.00
IUUC-Apl-004037 Anas platyrhynchos 53.69 0.00e+00 787.00
IUUC-Aca-004686 Anolis carolinensis 56.06 0.00e+00 795.00
IUUC-Ame-010641 Astyanax mexicanus 42.98 2.00e-164 573.00
IUUC-Bta-012779 Bos taurus 80.31 0.00e+00 1292.00
IUUC-Cja-019217 Callithrix jacchus 89.41 0.00e+00 1443.00
IUUC-Cfa-020613 Canis familiaris 82.45 0.00e+00 1256.00
IUUC-Cpo-022374 Cavia porcellus 77.31 0.00e+00 1211.00
IUUC-Cre-022690 Chlamydomonas reinhardtii 39.63 1.00e-66 248.00
IUUC-Csa-023471 Chlorocebus sabaeus 95.18 0.00e+00 1467.00
IUUC-Cho-024485 Choloepus hoffmanni 74.90 0.00e+00 1051.00
IUUC-Cin-025295 Ciona intestinalis 43.76 4.00e-164 572.00
IUUC-Csv-025888 Ciona savignyi 44.58 5.00e-168 584.00
IUUC-Dre-027657 Danio rerio 45.60 0.00e+00 630.00
IUUC-Dno-029422 Dasypus novemcinctus 76.39 0.00e+00 1156.00
IUUC-Ete-032340 Echinops telfairi 61.68 3.00e-115 409.00
IUUC-Eca-033418 Equus caballus 84.44 0.00e+00 1217.00
IUUC-Eeu-035088 Erinaceus europaeus 70.28 1.00e-154 540.00
IUUC-Fca-035471 Felis catus 82.02 0.00e+00 1284.00
IUUC-Fal-036908 Ficedula albicollis 48.51 6.00e-160 558.00
IUUC-Gmo-038672 Gadus morhua 40.30 2.00e-79 290.00
IUUC-Gga-040422 Gallus gallus 52.26 0.00e+00 724.00
IUUC-Gac-042448 Gasterosteus aculeatus 38.76 2.00e-146 513.00
IUUC-Ggo-045567 Gorilla gorilla 96.47 0.00e+00 1302.00
IUUC-Itr-048176 Ictidomys tridecemlineatus 87.68 0.00e+00 812.00
IUUC-Lch-050496 Latimeria chalumnae 56.51 0.00e+00 781.00
IUUC-Loc-052759 Lepisosteus oculatus 55.08 0.00e+00 749.00
IUUC-Laf-053515 Loxodonta africana 79.47 0.00e+00 1231.00
IUUC-Mcc-054741 Macaca mulatta 93.99 0.00e+00 1480.00
IUUC-Meu-056698 Macropus eugenii 77.58 7.00e-139 487.00
IUUC-Mga-059689 Meleagris gallopavo 52.14 0.00e+00 730.00
IUUC-Mmr-061641 Microcebus murinus 74.51 0.00e+00 873.00
IUUC-Mdo-061968 Monodelphis domestica 65.19 0.00e+00 982.00
IUUC-Mmu-063908 Mus musculus 73.65 0.00e+00 1076.00
IUUC-Mpu-065957 Mustela putorius furo 81.71 0.00e+00 1207.00
IUUC-Mlu-067454 Myotis lucifugus 76.26 0.00e+00 1201.00
IUUC-Nle-069312 Nomascus leucogenys 96.23 0.00e+00 1535.00
IUUC-Opr-070363 Ochotona princeps 65.61 0.00e+00 1031.00
IUUC-Ont-072322 Oreochromis niloticus 39.30 3.00e-146 512.00
IUUC-Oan-073666 Ornithorhynchus anatinus 63.36 0.00e+00 871.00
IUUC-Ocu-074719 Oryctolagus cuniculus 82.18 0.00e+00 1310.00
IUUC-Ola-087351 Oryzias latipes 43.83 3.00e-76 278.00
IUUC-Olu-087835 Ostreococcus lucimarinus 28.71 2.00e-36 146.00
IUUC-Oga-088476 Otolemur garnettii 74.20 0.00e+00 1030.00
IUUC-Oar-089261 Ovis aries 81.50 0.00e+00 1214.00
IUUC-Pan-091774 Papio anubis 95.06 0.00e+00 1486.00
IUUC-Psi-093526 Pelodiscus sinensis 54.38 0.00e+00 802.00
IUUC-Pma-094755 Petromyzon marinus 49.80 3.00e-69 254.00
IUUC-Ppa-095355 Physcomitrella patens 47.13 3.00e-39 155.00
IUUC-Pfo-096510 Poecilia formosa 37.63 2.00e-121 430.00
IUUC-Pab-098218 Pongo abelii 97.84 0.00e+00 1493.00
IUUC-Pva-102551 Pteropus vampyrus 84.51 0.00e+00 656.00
IUUC-Rno-105674 Rattus norvegicus 73.31 0.00e+00 1159.00
IUUC-Sha-107552 Sarcophilus harrisii 64.92 0.00e+00 977.00
IUUC-Smo-109353 Selaginella moellendorffii 42.48 1.00e-66 246.00
IUUC-Sar-113136 Sorex araneus 68.76 0.00e+00 932.00
IUUC-Ssc-116203 Sus scrofa 86.28 0.00e+00 1062.00
IUUC-Tgu-117141 Taeniopygia guttata 49.42 1.00e-167 583.00
IUUC-Tni-119670 Tetraodon nigroviridis 35.27 9.00e-101 360.00
IUUC-Tbe-127913 Tupaia belangeri 76.46 0.00e+00 915.00
IUUC-Ttr-128515 Tursiops truncatus 75.95 0.00e+00 1130.00
IUUC-Vpa-130560 Vicugna pacos 77.75 1.00e-176 613.00
IUUC-Xtr-131755 Xenopus tropicalis 53.43 0.00e+00 756.00
Created Date 25-Jun-2017

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