iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002126

Ensembl Protein ID

ENSAMEP00000008824.1

UniProt Accession

G1LP44; G1LP44_AILME

Genbank Protein ID

ENSAMEP00000008824

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01120932

Gene Name

UBASH3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000008362.1	ENSAMET00000009201.1	ENSAMEP00000008824.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.80e-06	28.0	27	64
UBD/SH3	8.10e-22	77.0	243	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++l+ l +MGF+r   ++aL+++ + +++aA+++L+++
   Q: 27   SALDVLLSMGFPRVSGQKALASTgGRSVQAACDWLFSH 64
           68999*******************************97 PP

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 243  NHETLQVIYPYTPQNDDELELSPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 306
           6899*********************************************************987 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

XXREELYSKV TPRRSRQQRP GTIKHGSALD VLLSMGFPRV SGQKALASTG GRSVQAACDW 60
LFSHVGDPFL DDPLPREYVL YLRPTGPLAQ KLSDFWQQSK QICGKNKAHN IFPHITLCQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNAGAG AGGAGCTGTA CAGCAAAGTC ACCCCGCGGA GGAGCCGCCA GCAGCGCCCG 60
GGCACCATCA AGCATGGATC GGCGCTGGAC GTGCTGCTCT CCATGGGCTT CCCGCGCGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9

SMART

SM00326--SH3

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004080	Anas platyrhynchos	90.62	0.00e+00	1106.00
IUUC-Aca-004828	Anolis carolinensis	83.28	0.00e+00	1036.00
IUUC-Ame-011030	Astyanax mexicanus	73.25	0.00e+00	819.00
IUUC-Bta-012370	Bos taurus	97.98	0.00e+00	1199.00
IUUC-Bci-013728	Botrytis cinerea	28.14	6.00e-10	58.20
IUUC-Cel-018530	Caenorhabditis elegans	39.69	6.00e-51	194.00
IUUC-Cja-018758	Callithrix jacchus	97.80	0.00e+00	1250.00
IUUC-Cfa-020544	Canis familiaris	98.45	0.00e+00	1031.00
IUUC-Cpo-022044	Cavia porcellus	97.65	0.00e+00	1190.00
IUUC-Csa-024169	Chlorocebus sabaeus	97.48	0.00e+00	1246.00
IUUC-Cho-024498	Choloepus hoffmanni	79.50	0.00e+00	894.00
IUUC-Cin-025372	Ciona intestinalis	41.22	2.00e-57	216.00
IUUC-Csv-026379	Ciona savignyi	43.34	5.00e-74	271.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	29.08	2.00e-08	53.10
IUUC-Dre-027539	Danio rerio	73.01	0.00e+00	986.00
IUUC-Dno-029808	Dasypus novemcinctus	95.26	0.00e+00	729.00
IUUC-Dor-030582	Dipodomys ordii	80.16	0.00e+00	997.00
IUUC-Dme-032201	Drosophila melanogaster	37.99	1.00e-64	241.00
IUUC-Ete-032740	Echinops telfairi	77.32	0.00e+00	999.00
IUUC-Eca-033743	Equus caballus	98.01	0.00e+00	1212.00
IUUC-Eeu-034505	Erinaceus europaeus	86.22	0.00e+00	702.00
IUUC-Fca-036519	Felis catus	98.11	0.00e+00	1280.00
IUUC-Fal-037295	Ficedula albicollis	89.43	0.00e+00	1095.00
IUUC-Gmo-038650	Gadus morhua	71.52	0.00e+00	909.00
IUUC-Gga-040179	Gallus gallus	89.31	0.00e+00	1169.00
IUUC-Gac-042180	Gasterosteus aculeatus	71.58	0.00e+00	924.00
IUUC-Ggo-044581	Gorilla gorilla	97.80	0.00e+00	1249.00
IUUC-Hsa-046526	Homo sapiens	97.64	0.00e+00	1249.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	95.90	0.00e+00	642.00
IUUC-Lch-049576	Latimeria chalumnae	79.74	0.00e+00	1008.00
IUUC-Loc-051854	Lepisosteus oculatus	78.86	0.00e+00	928.00
IUUC-Laf-054177	Loxodonta africana	96.06	0.00e+00	1257.00
IUUC-Mcc-055185	Macaca mulatta	97.64	0.00e+00	1249.00
IUUC-Meu-056216	Macropus eugenii	90.88	0.00e+00	1053.00
IUUC-Mga-059564	Meleagris gallopavo	90.27	0.00e+00	1102.00
IUUC-Mmr-060934	Microcebus murinus	97.17	0.00e+00	1244.00
IUUC-Mdo-062955	Monodelphis domestica	94.19	0.00e+00	1211.00
IUUC-Mmu-063301	Mus musculus	96.06	0.00e+00	1259.00
IUUC-Mpu-066416	Mustela putorius furo	98.58	0.00e+00	1282.00
IUUC-Mlu-067833	Myotis lucifugus	87.38	0.00e+00	1021.00
IUUC-Nle-069367	Nomascus leucogenys	97.17	0.00e+00	1243.00
IUUC-Opr-070879	Ochotona princeps	84.15	0.00e+00	745.00
IUUC-Ont-072540	Oreochromis niloticus	74.18	0.00e+00	944.00
IUUC-Oan-073124	Ornithorhynchus anatinus	89.54	0.00e+00	883.00
IUUC-Ocu-074796	Oryctolagus cuniculus	97.01	0.00e+00	1240.00
IUUC-Ola-087253	Oryzias latipes	72.54	0.00e+00	941.00
IUUC-Oga-088406	Otolemur garnettii	91.71	0.00e+00	1121.00
IUUC-Oar-090262	Ovis aries	97.32	0.00e+00	1245.00
IUUC-Ptr-091014	Pan troglodytes	97.80	0.00e+00	1249.00
IUUC-Pan-092684	Papio anubis	97.64	0.00e+00	1248.00
IUUC-Psi-093541	Pelodiscus sinensis	90.09	0.00e+00	1164.00
IUUC-Pma-094108	Petromyzon marinus	55.82	2.00e-152	532.00
IUUC-Pfo-097119	Poecilia formosa	71.81	0.00e+00	898.00
IUUC-Pab-097724	Pongo abelii	94.51	0.00e+00	1214.00
IUUC-Pca-100645	Procavia capensis	76.17	0.00e+00	721.00
IUUC-Pva-102322	Pteropus vampyrus	98.15	0.00e+00	1197.00
IUUC-Rno-105148	Rattus norvegicus	95.43	0.00e+00	1252.00
IUUC-Sha-106673	Sarcophilus harrisii	87.38	0.00e+00	1077.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.95	1.00e-08	53.50
IUUC-Sar-113746	Sorex araneus	76.55	4.00e-98	351.00
IUUC-Ssc-116425	Sus scrofa	97.35	0.00e+00	1210.00
IUUC-Tgu-116520	Taeniopygia guttata	87.74	0.00e+00	1127.00
IUUC-Tru-117750	Takifugu rubripes	67.12	0.00e+00	885.00
IUUC-Tsy-118975	Tarsius syrichta	96.97	0.00e+00	1161.00
IUUC-Tni-119830	Tetraodon nigroviridis	71.97	0.00e+00	905.00
IUUC-Tbe-127895	Tupaia belangeri	96.30	7.00e-131	461.00
IUUC-Ttr-129103	Tursiops truncatus	97.01	0.00e+00	1270.00
IUUC-Vpa-130720	Vicugna pacos	98.98	1.00e-114	406.00
IUUC-Xtr-132314	Xenopus tropicalis	82.89	0.00e+00	1098.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence