iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091014

Ensembl Protein ID

ENSPTRP00000007535.4

UniProt Accession

H2Q4Z7; H2Q4Z7_PANTR

Genbank Protein ID

JAA06879.1; JAA12019.1; JAA26087.1; JAA37817.1

Protein Name

Ubiquitin associated and SH3 domain containing B

Genbank Nucleotide ID

AACZ03082181; GABF01010126; GABD01007013; GABE01006922

Gene Name

UBASH3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000004400.4	ENSPTRT00000008162.4	ENSPTRP00000007535.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.10e-09	36.0	39	76
UBD/SH3	8.90e-22	76.8	255	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++l+ l +MGF+r +a++aL+++ + +++aA+++L+++
   Q: 39   SALDVLLSMGFPRARAQKALASTgGRSVQAACDWLFSH 76
           68999*******************************97 PP

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 255  NHETLQVIYPYTPQNDDELELVPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 318
           6899*********************************************************987 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAQYGHPSPL GMAAREELYS KVTPRRNRQQ RPGTIKHGSA LDVLLSMGFP RARAQKALAS 60
TGGRSVQAAC DWLFSHVGDP FLDDPLPREY VLYLRPTGPL AQKLSDFWQQ SKQICGKNKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTCCTTT TTGATCCATT CAAAAATTAC TCATTGCAAA TTCCCGGACT GCTAGGCGAG 60
GAGAGGGAAG GGGGCGGAGG AGACAGGGCT ACTGCAGGCG CAGCGCTGGG GGCAGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9
PF00627--UBA

SMART

SM00326--SH3
SM00165--UBA

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002126	Ailuropoda melanoleuca	97.80	0.00e+00	1277.00
IUUC-Apl-004080	Anas platyrhynchos	91.29	0.00e+00	1113.00
IUUC-Aca-004828	Anolis carolinensis	84.27	0.00e+00	1045.00
IUUC-Ame-011030	Astyanax mexicanus	74.17	0.00e+00	828.00
IUUC-Bta-012370	Bos taurus	97.98	0.00e+00	1201.00
IUUC-Bci-013728	Botrytis cinerea	28.14	5.00e-10	58.20
IUUC-Cel-018530	Caenorhabditis elegans	39.69	4.00e-51	194.00
IUUC-Cja-018758	Callithrix jacchus	99.69	0.00e+00	1298.00
IUUC-Cfa-020544	Canis familiaris	97.48	0.00e+00	1024.00
IUUC-Cpo-022044	Cavia porcellus	98.49	0.00e+00	1200.00
IUUC-Csa-024169	Chlorocebus sabaeus	99.69	0.00e+00	1296.00
IUUC-Cho-024498	Choloepus hoffmanni	80.84	0.00e+00	904.00
IUUC-Cin-025372	Ciona intestinalis	41.22	7.00e-58	218.00
IUUC-Csv-026379	Ciona savignyi	43.65	2.00e-75	275.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	29.08	2.00e-08	53.10
IUUC-Dre-027539	Danio rerio	73.91	0.00e+00	1008.00
IUUC-Dno-029808	Dasypus novemcinctus	97.52	0.00e+00	749.00
IUUC-Dor-030582	Dipodomys ordii	80.72	0.00e+00	1018.00
IUUC-Dme-032201	Drosophila melanogaster	38.61	2.00e-65	243.00
IUUC-Ete-032740	Echinops telfairi	78.83	0.00e+00	1034.00
IUUC-Eca-033743	Equus caballus	98.51	0.00e+00	1219.00
IUUC-Eeu-034505	Erinaceus europaeus	85.97	0.00e+00	701.00
IUUC-Fca-036519	Felis catus	97.69	0.00e+00	1307.00
IUUC-Fal-037295	Ficedula albicollis	89.29	0.00e+00	1106.00
IUUC-Gmo-038650	Gadus morhua	72.43	0.00e+00	929.00
IUUC-Gga-040179	Gallus gallus	90.61	0.00e+00	1191.00
IUUC-Gac-042180	Gasterosteus aculeatus	72.49	0.00e+00	941.00
IUUC-Ggo-044581	Gorilla gorilla	100.00	0.00e+00	1301.00
IUUC-Hsa-046526	Homo sapiens	99.85	0.00e+00	1300.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	97.79	0.00e+00	652.00
IUUC-Lch-049576	Latimeria chalumnae	80.56	0.00e+00	1017.00
IUUC-Loc-051854	Lepisosteus oculatus	79.36	0.00e+00	934.00
IUUC-Laf-054177	Loxodonta africana	97.49	0.00e+00	1278.00
IUUC-Mcc-055185	Macaca mulatta	99.69	0.00e+00	1297.00
IUUC-Meu-056216	Macropus eugenii	92.07	0.00e+00	1087.00
IUUC-Mga-059564	Meleagris gallopavo	90.94	0.00e+00	1110.00
IUUC-Mmr-060934	Microcebus murinus	99.08	0.00e+00	1292.00
IUUC-Mdo-062955	Monodelphis domestica	95.62	0.00e+00	1233.00
IUUC-Mmu-063301	Mus musculus	97.81	0.00e+00	1286.00
IUUC-Mpu-066416	Mustela putorius furo	98.00	0.00e+00	1308.00
IUUC-Mlu-067833	Myotis lucifugus	87.71	0.00e+00	1028.00
IUUC-Nle-069367	Nomascus leucogenys	99.38	0.00e+00	1293.00
IUUC-Opr-070879	Ochotona princeps	85.71	0.00e+00	756.00
IUUC-Ont-072540	Oreochromis niloticus	74.92	0.00e+00	961.00
IUUC-Oan-073124	Ornithorhynchus anatinus	90.79	0.00e+00	896.00
IUUC-Ocu-074796	Oryctolagus cuniculus	98.43	0.00e+00	1260.00
IUUC-Ola-087253	Oryzias latipes	73.49	0.00e+00	961.00
IUUC-Oga-088406	Otolemur garnettii	93.03	0.00e+00	1134.00
IUUC-Oar-090262	Ovis aries	98.00	0.00e+00	1285.00
IUUC-Pan-092684	Papio anubis	99.85	0.00e+00	1299.00
IUUC-Psi-093541	Pelodiscus sinensis	90.00	0.00e+00	1196.00
IUUC-Pma-094108	Petromyzon marinus	56.02	1.00e-152	532.00
IUUC-Pfo-097119	Poecilia formosa	72.56	0.00e+00	915.00
IUUC-Pab-097724	Pongo abelii	96.47	0.00e+00	1264.00
IUUC-Pca-100645	Procavia capensis	76.78	0.00e+00	726.00
IUUC-Pva-102322	Pteropus vampyrus	98.15	0.00e+00	1199.00
IUUC-Rno-105148	Rattus norvegicus	96.87	0.00e+00	1276.00
IUUC-Sha-106673	Sarcophilus harrisii	87.86	0.00e+00	1085.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.95	1.00e-08	53.50
IUUC-Sar-113746	Sorex araneus	76.99	3.00e-99	354.00
IUUC-Ssc-116425	Sus scrofa	98.01	0.00e+00	1217.00
IUUC-Tgu-116520	Taeniopygia guttata	89.08	0.00e+00	1152.00
IUUC-Tru-117750	Takifugu rubripes	67.77	0.00e+00	898.00
IUUC-Tsy-118975	Tarsius syrichta	98.15	0.00e+00	1174.00
IUUC-Tni-119830	Tetraodon nigroviridis	72.88	0.00e+00	920.00
IUUC-Tbe-127895	Tupaia belangeri	96.44	5.00e-136	478.00
IUUC-Ttr-129103	Tursiops truncatus	97.69	0.00e+00	1308.00
IUUC-Vpa-130720	Vicugna pacos	98.47	1.00e-113	403.00
IUUC-Xtr-132314	Xenopus tropicalis	83.75	0.00e+00	1114.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence