iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066122

Ensembl Protein ID

ENSMPUP00000000261.1

UniProt Accession

M3XMG1; M3XMG1_MUSPF

Genbank Protein ID

ENSMPUP00000000261

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01091607

Gene Name

UBE2L6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000263.1	ENSMPUT00000000265.1	ENSMPUP00000000261.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.50e-38	129.4	6	141

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l+++ p++++  + d++d+  w+vl+l pe+ pY+ ++F+++i+fp+dYPfkPP+v+f+t+i+hPnv ++G+vCl i+ ++
   Q: 6    RVAKELEDLQAELPPYLRNLFIDDADVLVWHVLLL-PEEPPYNLKAFHVRISFPKDYPFKPPTVTFTTRIYHPNVGHDGSVCLPII-SR 92
           899********************************.**************************************************.59 PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           e+W+p ++ ++vl ++  l+++p   +p + e a+ll +n+e++++++r
   Q: 93   ENWQPHTKTSQVLEALSVLVNRPDLGQPIRLELADLLAENPERFNSEAR 141
           *********************************************9987 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLASKRVAKE LEDLQAELPP YLRNLFIDDA DVLVWHVLLL PEEPPYNLKA FHVRISFPKD 60
YPFKPPTVTF TTRIYHPNVG HDGSVCLPII SRENWQPHTK TSQVLEALSV LVNRPDLGQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCGCCGA GGGGCGGGGC TCATGGGGCG GGGCGCACCG AGGAAGCCGG GCTCCGGGGC 60
GGGGCGCGGC GAGGGGCCGC GCGGGACCTC AGTCCTGCTG GAGCGCACGG AAGCCTCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001818	Ailuropoda melanoleuca	84.46	3.00e-72	263.00
IUUC-Apl-003318	Anas platyrhynchos	47.18	1.00e-28	118.00
IUUC-Aca-005034	Anolis carolinensis	53.38	6.00e-40	155.00
IUUC-Ame-011622	Astyanax mexicanus	45.95	8.00e-28	115.00
IUUC-Bta-012539	Bos taurus	68.92	2.00e-58	217.00
IUUC-Cel-018332	Caenorhabditis elegans	45.95	7.00e-36	142.00
IUUC-Cja-019456	Callithrix jacchus	70.95	1.00e-60	224.00
IUUC-Cfa-021275	Canis familiaris	84.46	1.00e-72	264.00
IUUC-Cpo-022261	Cavia porcellus	66.22	6.00e-56	209.00
IUUC-Csa-023794	Chlorocebus sabaeus	69.39	2.00e-57	214.00
IUUC-Cho-024821	Choloepus hoffmanni	69.78	2.00e-54	204.00
IUUC-Cin-025130	Ciona intestinalis	46.62	5.00e-27	113.00
IUUC-Csv-026183	Ciona savignyi	43.92	1.00e-23	102.00
IUUC-Dre-027710	Danio rerio	45.95	2.00e-30	124.00
IUUC-Dno-029632	Dasypus novemcinctus	72.97	2.00e-60	223.00
IUUC-Dor-030595	Dipodomys ordii	63.55	9.00e-40	155.00
IUUC-Dme-031814	Drosophila melanogaster	46.62	5.00e-38	149.00
IUUC-Ete-032754	Echinops telfairi	47.97	2.00e-31	127.00
IUUC-Eca-033746	Equus caballus	75.00	2.00e-63	234.00
IUUC-Eeu-034942	Erinaceus europaeus	47.97	4.00e-31	127.00
IUUC-Fca-035417	Felis catus	83.11	2.00e-70	257.00
IUUC-Fal-036820	Ficedula albicollis	47.48	2.00e-28	117.00
IUUC-Gmo-038480	Gadus morhua	43.88	2.00e-25	108.00
IUUC-Gga-041039	Gallus gallus	47.97	2.00e-31	127.00
IUUC-Gac-041571	Gasterosteus aculeatus	44.14	9.00e-26	108.00
IUUC-Ggo-045537	Gorilla gorilla	69.59	4.00e-60	223.00
IUUC-Hsa-045943	Homo sapiens	68.24	5.00e-59	219.00
IUUC-Itr-048889	Ictidomys tridecemlineatus	65.54	6.00e-56	209.00
IUUC-Lch-049699	Latimeria chalumnae	50.00	2.00e-20	91.70
IUUC-Loc-052000	Lepisosteus oculatus	46.00	6.00e-29	120.00
IUUC-Laf-053524	Loxodonta africana	65.54	3.00e-51	194.00
IUUC-Mcc-054818	Macaca mulatta	68.71	5.00e-57	212.00
IUUC-Meu-055936	Macropus eugenii	53.27	7.00e-31	125.00
IUUC-Mga-060134	Meleagris gallopavo	47.30	1.00e-28	118.00
IUUC-Mmr-060799	Microcebus murinus	71.62	3.00e-61	226.00
IUUC-Mdo-062043	Monodelphis domestica	39.23	4.00e-26	110.00
IUUC-Mmu-063359	Mus musculus	70.27	4.00e-59	219.00
IUUC-Mlu-067283	Myotis lucifugus	75.68	3.00e-63	233.00
IUUC-Nle-069829	Nomascus leucogenys	70.27	2.00e-59	221.00
IUUC-Opr-071062	Ochotona princeps	68.92	3.00e-57	213.00
IUUC-Ont-072036	Oreochromis niloticus	45.95	8.00e-30	122.00
IUUC-Oan-073297	Ornithorhynchus anatinus	64.81	2.00e-37	146.00
IUUC-Ocu-074709	Oryctolagus cuniculus	67.86	3.00e-54	203.00
IUUC-Ola-086994	Oryzias latipes	44.59	4.00e-36	143.00
IUUC-Oga-088256	Otolemur garnettii	66.89	1.00e-57	215.00
IUUC-Oar-089370	Ovis aries	65.00	2.00e-52	197.00
IUUC-Ptr-091324	Pan troglodytes	68.24	5.00e-59	219.00
IUUC-Pan-092601	Papio anubis	68.57	3.00e-54	203.00
IUUC-Psi-093989	Pelodiscus sinensis	50.71	2.00e-31	127.00
IUUC-Pma-094445	Petromyzon marinus	44.12	5.00e-25	106.00
IUUC-Pfo-097407	Poecilia formosa	46.62	9.00e-31	125.00
IUUC-Pab-098184	Pongo abelii	68.92	1.00e-59	221.00
IUUC-Pca-101080	Procavia capensis	65.47	4.00e-53	199.00
IUUC-Pva-102211	Pteropus vampyrus	71.03	3.00e-42	163.00
IUUC-Rno-104863	Rattus norvegicus	67.57	9.00e-58	215.00
IUUC-Sha-107162	Sarcophilus harrisii	53.38	9.00e-43	165.00
IUUC-Sar-113240	Sorex araneus	47.48	2.00e-28	117.00
IUUC-Ssc-115506	Sus scrofa	75.00	7.00e-63	232.00
IUUC-Tgu-117352	Taeniopygia guttata	47.14	2.00e-28	117.00
IUUC-Tru-117653	Takifugu rubripes	46.62	7.00e-30	122.00
IUUC-Tsy-118811	Tarsius syrichta	56.12	1.00e-41	161.00
IUUC-Tni-120844	Tetraodon nigroviridis	49.32	3.00e-41	160.00
IUUC-Tbe-127294	Tupaia belangeri	47.86	5.00e-29	119.00
IUUC-Ttr-129266	Tursiops truncatus	77.70	3.00e-66	243.00
IUUC-Vpa-130649	Vicugna pacos	77.45	1.00e-43	167.00
IUUC-Xtr-132650	Xenopus tropicalis	47.30	3.00e-31	127.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence