iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000012126.16	ENSMUST00000074690.10	ENSMUSP00000074255.4
ENSMUSG00000012126.16	ENSMUST00000070246.8	ENSMUSP00000064030.2
ENSMUSG00000012126.16	ENSMUST00000156750.1	ENSMUSP00000117081.1
ENSMUSG00000012126.16	ENSMUST00000151113.1	ENSMUSP00000122892.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	4.00e-10	41.2	394	466

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 6    atlqiRlpdGkr.lvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           ++l+i+ ++G++ +  ++ +++t+ ++++ +++++ ++s  Fe++s+fP   +++++   tlq agLvp+++ll+
   Q: 394  SMLRIKSENGEQaFLLMMWPEDTIGDVRKLLAQARDMDSAAFEILSTFPPTVYQDDTV--TLQAAGLVPNATLLL 466
           789*********9*********************************************..*************97 PP

Organism

Mus musculus

Functional Description
(View)

May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).

Protein Sequence
(Fasta)

MSSPLASLSK TRKVPLESES VNPGRRGIRV YGNEDEVDMW NDGQDSEEKI SLPSCYGGIG 60
APVSRQGPHD SELMASMTRK LQELEQQLQA QNDEMLSKER KILDLEDLVQ TLQQHQNNAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTGCTCGG GTCCTGGTCG CCTGGGAAAC CCCGAGACAA CAAGATGGCG GCGCCGCGGG 60
ACGGCTCGCT GGCCCCGTGG TGAGTGCCAT CTCCGGGCCT TTCTGCCCCG CTAAGTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0043130--F:ubiquitin binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

mmu:67586

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002106	Ailuropoda melanoleuca	75.00	0.00e+00	673.00
IUUC-Apl-004013	Anas platyrhynchos	43.95	3.00e-85	308.00
IUUC-Aca-004665	Anolis carolinensis	48.89	4.00e-57	214.00
IUUC-Aly-005847	Arabidopsis lyrata	32.89	1.50e-02	33.10
IUUC-Ath-006745	Arabidopsis thaliana	30.95	1.10e-02	33.50
IUUC-Ame-011360	Astyanax mexicanus	30.77	7.00e-46	177.00
IUUC-Bta-013401	Bos taurus	75.65	0.00e+00	699.00
IUUC-Bol-015349	Brassica oleracea	31.17	2.00e-03	36.60
IUUC-Bra-017646	Brassica rapa	28.57	4.00e-03	35.00
IUUC-Cja-018782	Callithrix jacchus	78.45	0.00e+00	724.00
IUUC-Cfa-020771	Canis familiaris	71.52	0.00e+00	634.00
IUUC-Cpo-022096	Cavia porcellus	76.08	0.00e+00	662.00
IUUC-Cre-022692	Chlamydomonas reinhardtii	35.29	4.00e-16	79.30
IUUC-Csa-024247	Chlorocebus sabaeus	82.11	0.00e+00	731.00
IUUC-Cin-025602	Ciona intestinalis	36.39	2.00e-70	259.00
IUUC-Csv-026269	Ciona savignyi	35.71	1.00e-08	51.20
IUUC-Dre-027891	Danio rerio	35.12	5.00e-70	258.00
IUUC-Dno-029857	Dasypus novemcinctus	78.95	9.00e-131	459.00
IUUC-Dor-030412	Dipodomys ordii	74.37	2.00e-143	502.00
IUUC-Ete-032458	Echinops telfairi	71.83	6.00e-110	390.00
IUUC-Eca-033588	Equus caballus	67.31	1.00e-174	605.00
IUUC-Eeu-034987	Erinaceus europaeus	67.65	3.00e-53	202.00
IUUC-Fca-036191	Felis catus	77.80	0.00e+00	706.00
IUUC-Fal-036787	Ficedula albicollis	40.98	3.00e-64	239.00
IUUC-Gmo-039684	Gadus morhua	36.62	2.00e-57	215.00
IUUC-Ggo-045292	Gorilla gorilla	81.68	0.00e+00	753.00
IUUC-Hsa-046321	Homo sapiens	82.11	0.00e+00	756.00
IUUC-Itr-048346	Ictidomys tridecemlineatus	74.89	0.00e+00	669.00
IUUC-Lch-050451	Latimeria chalumnae	37.98	6.00e-82	298.00
IUUC-Loc-052426	Lepisosteus oculatus	43.23	6.00e-75	275.00
IUUC-Laf-054529	Loxodonta africana	75.43	0.00e+00	707.00
IUUC-Mcc-055816	Macaca mulatta	83.09	4.00e-136	477.00
IUUC-Meu-056554	Macropus eugenii	53.51	6.00e-62	231.00
IUUC-Mga-059465	Meleagris gallopavo	43.32	6.00e-80	291.00
IUUC-Mmr-061200	Microcebus murinus	82.76	0.00e+00	770.00
IUUC-Mdo-062251	Monodelphis domestica	48.20	2.00e-102	366.00
IUUC-Mpu-065893	Mustela putorius furo	70.59	0.00e+00	687.00
IUUC-Mlu-067272	Myotis lucifugus	71.12	0.00e+00	634.00
IUUC-Nle-069502	Nomascus leucogenys	79.09	0.00e+00	741.00
IUUC-Opr-070633	Ochotona princeps	75.00	1.00e-109	389.00
IUUC-Ont-071974	Oreochromis niloticus	34.02	2.00e-71	263.00
IUUC-Ocu-073992	Oryctolagus cuniculus	77.20	0.00e+00	719.00
IUUC-Oga-088667	Otolemur garnettii	77.45	0.00e+00	723.00
IUUC-Oar-089434	Ovis aries	72.63	0.00e+00	629.00
IUUC-Ptr-090611	Pan troglodytes	81.68	0.00e+00	749.00
IUUC-Pan-092364	Papio anubis	81.82	0.00e+00	699.00
IUUC-Psi-093473	Pelodiscus sinensis	45.07	2.00e-102	366.00
IUUC-Pfo-096635	Poecilia formosa	32.85	4.00e-61	228.00
IUUC-Pab-097570	Pongo abelii	81.68	0.00e+00	757.00
IUUC-Pca-101026	Procavia capensis	75.56	2.00e-74	273.00
IUUC-Pva-102579	Pteropus vampyrus	68.73	1.00e-127	449.00
IUUC-Pte-104066	Pyrenophora teres	30.00	3.80e-01	31.60
IUUC-Rno-105252	Rattus norvegicus	87.37	0.00e+00	815.00
IUUC-Sha-107615	Sarcophilus harrisii	46.99	3.00e-68	252.00
IUUC-Sar-113037	Sorex araneus	53.64	6.00e-112	397.00
IUUC-Tsy-119106	Tarsius syrichta	68.31	5.00e-99	354.00
IUUC-Ttr-128789	Tursiops truncatus	73.81	0.00e+00	651.00
IUUC-Xtr-131876	Xenopus tropicalis	39.57	9.00e-74	270.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence