iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012347

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02028582

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000021087.4	ENSBTAT00000028086.4	ENSBTAP00000028086.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	2.20e-40	136.8	215	291
E3 activity/RING/RING	1.80e-08	34.9	1090	1193
E3 activity/N-recognin/UBR-box	5.10e-31	107.1	86	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al++e++ea+ ++t+idkeGRravkaG++a+c+eak++i+++se+++q+pL+Vev
   Q: 215  YYCVLFNDEHHSYDHVIYSLQRALDCELAEAQMHTTAIDKEGRRAVKAGAFAACQEAKEDIKSHSENVSQHPLHVEV 291
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiCledf...............kd..............................gplvlpCgHvfhadClqkw............. 29
           C++C+e+                ++                              g+++++CgHv+ha C+qk+             
   Q: 1090 CILCQEEQevkiennamvlsacvQKstaltqhrgkpielsgetidplfmdadlayGTYTGSCGHVMHAVCWQKYfeavqlssqqrih 1176
           77885555444433333333333003333333333333333333333333333338999**************************** PP
   S: 30   pglknssskefrCPlCr 46
           ++l +++s+e +CPlC+
   Q: 1177 VDLFDLESGEYLCPLCK 1193
           ****************7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk+get+y+Cr+C++d+t+vlC++Cf+++vHk+H+yk+++s+gggfCdCGdteAw++g++C +++
   Q: 86   QLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQNSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCISHE 156
           68*****************************************************************9986 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MEISTELPQT PQQLASCWDQ QIDFYTIFLN YLAQVVPDIY FAEMDPDLEK QEESIQRSIF 60
TPLEWYLFGE DPDICLEKLK HSGAFQLCGK VFKSGETTYS CRDCAIDPTC VLCMDCFQNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGACGAGG AGGCTGGGGA CACAGAGAGG ATGGAAATCA GCACGGAGTT GCCGCAGACC 60
CCTCAGCAAC TGGCGTCTGT AAGTCCCTGA AGGCCAGTTC CTTTTGTAAC CTCCCCGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	94.83	0.00e+00	3325.00
IUUC-Apl-004160	Anas platyrhynchos	77.79	0.00e+00	2731.00
IUUC-Aca-004982	Anolis carolinensis	74.68	0.00e+00	2633.00
IUUC-Acl-008055	Aspergillus clavatus	23.98	2.00e-35	145.00
IUUC-Ate-010550	Aspergillus terreus	22.96	6.00e-48	187.00
IUUC-Ame-011231	Astyanax mexicanus	57.22	0.00e+00	1880.00
IUUC-Bgr-011999	Blumeria graminis	23.35	2.00e-47	186.00
IUUC-Bci-013834	Botrytis cinerea	23.33	5.00e-43	171.00
IUUC-Cja-018911	Callithrix jacchus	89.55	0.00e+00	3147.00
IUUC-Cfa-020991	Canis familiaris	95.75	0.00e+00	3358.00
IUUC-Cpo-021448	Cavia porcellus	91.43	0.00e+00	3222.00
IUUC-Csa-024255	Chlorocebus sabaeus	93.71	0.00e+00	2719.00
IUUC-Cho-024550	Choloepus hoffmanni	72.62	0.00e+00	2428.00
IUUC-Dno-029427	Dasypus novemcinctus	92.18	0.00e+00	3167.00
IUUC-Dor-031073	Dipodomys ordii	79.56	0.00e+00	1390.00
IUUC-Ete-032318	Echinops telfairi	75.06	0.00e+00	1233.00
IUUC-Eca-033348	Equus caballus	95.00	0.00e+00	3105.00
IUUC-Eeu-034664	Erinaceus europaeus	84.91	0.00e+00	2981.00
IUUC-Fca-035604	Felis catus	94.14	0.00e+00	1553.00
IUUC-Fal-037333	Ficedula albicollis	77.52	0.00e+00	2696.00
IUUC-Fox-037984	Fusarium oxysporum	27.03	3.00e-41	165.00
IUUC-Fso-038463	Fusarium solani	25.38	2.00e-43	172.00
IUUC-Gmo-039363	Gadus morhua	55.59	0.00e+00	1635.00
IUUC-Gga-040486	Gallus gallus	76.82	0.00e+00	2649.00
IUUC-Gac-041985	Gasterosteus aculeatus	57.05	0.00e+00	1732.00
IUUC-Ggo-044704	Gorilla gorilla	87.05	0.00e+00	2560.00
IUUC-Hsa-046753	Homo sapiens	94.09	0.00e+00	3313.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	93.87	0.00e+00	3284.00
IUUC-Lch-049904	Latimeria chalumnae	61.83	0.00e+00	2118.00
IUUC-Loc-052624	Lepisosteus oculatus	61.09	0.00e+00	2051.00
IUUC-Laf-053857	Loxodonta africana	90.39	0.00e+00	3175.00
IUUC-Mcc-054873	Macaca mulatta	93.92	0.00e+00	3269.00
IUUC-Meu-056858	Macropus eugenii	67.04	0.00e+00	1032.00
IUUC-Mga-059917	Meleagris gallopavo	77.25	0.00e+00	2758.00
IUUC-Mmr-061128	Microcebus murinus	90.53	0.00e+00	3123.00
IUUC-Mdo-062306	Monodelphis domestica	80.70	0.00e+00	2822.00
IUUC-Mmu-063389	Mus musculus	91.24	0.00e+00	3234.00
IUUC-Mpu-065983	Mustela putorius furo	95.58	0.00e+00	3375.00
IUUC-Mlu-068013	Myotis lucifugus	91.63	0.00e+00	3219.00
IUUC-Nle-070031	Nomascus leucogenys	94.32	0.00e+00	3321.00
IUUC-Opr-070551	Ochotona princeps	70.50	0.00e+00	1353.00
IUUC-Ont-072035	Oreochromis niloticus	57.77	0.00e+00	1956.00
IUUC-Ocu-074930	Oryctolagus cuniculus	89.18	0.00e+00	3105.00
IUUC-Oba-075295	Oryza barthii	38.54	5.00e-14	74.70
IUUC-Ogu-078497	Oryza glumaepatula	38.54	4.00e-14	74.70
IUUC-Oin-079343	Oryza indica	38.54	5.00e-14	74.30
IUUC-Oni-083099	Oryza nivara	38.54	5.00e-14	74.70
IUUC-Oru-084471	Oryza rufipogon	38.54	5.00e-14	74.70
IUUC-Osa-086106	Oryza sativa	36.03	2.00e-13	71.20
IUUC-Ola-086683	Oryzias latipes	57.36	0.00e+00	1895.00
IUUC-Oga-088017	Otolemur garnettii	90.01	0.00e+00	3121.00
IUUC-Oar-089557	Ovis aries	98.34	0.00e+00	3444.00
IUUC-Ptr-091366	Pan troglodytes	93.00	0.00e+00	3290.00
IUUC-Pan-092184	Papio anubis	93.92	0.00e+00	3267.00
IUUC-Psi-093720	Pelodiscus sinensis	77.68	0.00e+00	2680.00
IUUC-Pfo-097124	Poecilia formosa	57.44	0.00e+00	1922.00
IUUC-Pab-098586	Pongo abelii	94.32	0.00e+00	3317.00
IUUC-Pop-099184	Populus trichocarpa	44.21	1.00e-13	70.50
IUUC-Pca-100673	Procavia capensis	84.07	0.00e+00	1703.00
IUUC-Pva-102724	Pteropus vampyrus	88.81	0.00e+00	3066.00
IUUC-Pte-104174	Pyrenophora teres	23.54	3.00e-47	184.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	23.49	2.00e-46	182.00
IUUC-Rno-105474	Rattus norvegicus	88.65	0.00e+00	2341.00
IUUC-Sha-106993	Sarcophilus harrisii	80.85	0.00e+00	2899.00
IUUC-Sar-113447	Sorex araneus	88.76	0.00e+00	2159.00
IUUC-Ssc-115768	Sus scrofa	91.75	0.00e+00	2995.00
IUUC-Tgu-116949	Taeniopygia guttata	72.74	0.00e+00	2473.00
IUUC-Tru-117782	Takifugu rubripes	57.03	0.00e+00	1925.00
IUUC-Tsy-119177	Tarsius syrichta	82.93	0.00e+00	2247.00
IUUC-Tni-120884	Tetraodon nigroviridis	53.25	0.00e+00	1753.00
IUUC-Tre-122137	Trichoderma reesei	25.00	1.00e-59	226.00
IUUC-Tbe-128088	Tupaia belangeri	82.34	0.00e+00	1268.00
IUUC-Ttr-129062	Tursiops truncatus	90.76	0.00e+00	3133.00
IUUC-Uma-129344	Ustilago maydis	23.75	4.00e-57	218.00
IUUC-Vpa-130578	Vicugna pacos	88.12	0.00e+00	3007.00
IUUC-Vvi-130900	Vitis vinifera	44.79	9.00e-13	67.80
IUUC-Xtr-132244	Xenopus tropicalis	60.73	0.00e+00	2090.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence