iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088017

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03084785

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000005196.2	ENSOGAT00000005207.2	ENSOGAP00000004652.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	3.00e-40	136.3	226	302
E3 activity/RING/RING	1.70e-08	34.8	1101	1204
E3 activity/N-recognin/UBR-box	1.90e-31	108.4	97	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al++e++ea++++t+idkeGRravkaG+y +c+eak++i+++se+++q+pL+Vev
   Q: 226  YYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGVYSACQEAKEDIKSHSENVSQHPLHVEV 302
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiCledf...............kd..............................gplvlpCgHvfhadClqkw............. 29
           C++C+e+                ++                              g+++++CgHv+ha C+qk+             
   Q: 1101 CILCQEEQevkiennamvlsacvQKstaltqhrgkpvelsgetldplfmdpdlayGTYTGSCGHVMHAVCWQKYfeavqlssqqrih 1187
           78885554433333333333222002333333333333333333333333333337999**************************** PP
   S: 30   pglknssskefrCPlCr 46
           ++l +++s+e +CPlC+
   Q: 1188 VDLFDLESGEYLCPLCK 1204
           ****************7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk+get+y+Cr+C++d+t+vlC++Cf+++vHk+H+yk+++s+gggfCdCGdteAw++g++C++++
   Q: 97   QLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQNSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVNHE 167
           68*******************************************************************96 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

LTDDELTFTQ QDPAIPEAIF SPQYLWYWWD QQIDFYTAFL HHLAQLVPEI YFAEMDPDLE 60
KQEENVQMSI FTPLEWYLFG EDPDICLERL KHSGAFQLCG KVFKSGETTY SCRDCAIDPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGACTGATG ATGAACTCAC CTTCACACAG CAGGACCCAG CCATTCCGGA AGGGAAGGGT 60
AATTCTCATC TACTACAGCT ATTTTTTCCC CCCAATATCT GTGGTATGTG GGTAACTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	90.01	0.00e+00	3126.00
IUUC-Apl-004160	Anas platyrhynchos	75.40	0.00e+00	2602.00
IUUC-Aca-004982	Anolis carolinensis	72.74	0.00e+00	2503.00
IUUC-Acl-008055	Aspergillus clavatus	22.38	2.00e-40	162.00
IUUC-Ate-010550	Aspergillus terreus	22.63	1.00e-39	159.00
IUUC-Ame-011231	Astyanax mexicanus	55.79	0.00e+00	1537.00
IUUC-Bta-012347	Bos taurus	90.47	0.00e+00	3122.00
IUUC-Cja-018911	Callithrix jacchus	87.32	0.00e+00	2996.00
IUUC-Cfa-020991	Canis familiaris	90.69	0.00e+00	3151.00
IUUC-Cpo-021448	Cavia porcellus	88.59	0.00e+00	3083.00
IUUC-Cre-022930	Chlamydomonas reinhardtii	46.15	2.30e-02	30.80
IUUC-Csa-024255	Chlorocebus sabaeus	93.41	0.00e+00	2679.00
IUUC-Cho-024550	Choloepus hoffmanni	68.79	0.00e+00	1902.00
IUUC-Dno-029427	Dasypus novemcinctus	89.17	0.00e+00	3013.00
IUUC-Dor-031073	Dipodomys ordii	76.96	0.00e+00	1322.00
IUUC-Ete-032318	Echinops telfairi	72.80	0.00e+00	1165.00
IUUC-Eca-033348	Equus caballus	90.46	0.00e+00	2912.00
IUUC-Eeu-034664	Erinaceus europaeus	81.45	0.00e+00	2798.00
IUUC-Fca-035604	Felis catus	86.81	0.00e+00	2916.00
IUUC-Fal-037333	Ficedula albicollis	75.41	0.00e+00	2567.00
IUUC-Gmo-039363	Gadus morhua	53.33	0.00e+00	1539.00
IUUC-Gga-040486	Gallus gallus	74.71	0.00e+00	2521.00
IUUC-Gac-041985	Gasterosteus aculeatus	54.31	0.00e+00	1632.00
IUUC-Ggo-044704	Gorilla gorilla	86.82	0.00e+00	2460.00
IUUC-Hsa-046753	Homo sapiens	90.69	0.00e+00	3151.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	89.95	0.00e+00	3114.00
IUUC-Lch-049904	Latimeria chalumnae	59.15	0.00e+00	1967.00
IUUC-Loc-052624	Lepisosteus oculatus	58.31	0.00e+00	1934.00
IUUC-Laf-053857	Loxodonta africana	87.53	0.00e+00	3023.00
IUUC-Mcc-054873	Macaca mulatta	90.63	0.00e+00	3108.00
IUUC-Meu-056858	Macropus eugenii	67.55	0.00e+00	1038.00
IUUC-Mga-059917	Meleagris gallopavo	75.66	0.00e+00	2634.00
IUUC-Mmr-061128	Microcebus murinus	87.96	0.00e+00	2988.00
IUUC-Mdo-062306	Monodelphis domestica	78.93	0.00e+00	2705.00
IUUC-Mmu-063389	Mus musculus	88.47	0.00e+00	3100.00
IUUC-Mpu-065983	Mustela putorius furo	90.63	0.00e+00	3167.00
IUUC-Mlu-068013	Myotis lucifugus	86.73	0.00e+00	3026.00
IUUC-Nle-070031	Nomascus leucogenys	91.14	0.00e+00	3170.00
IUUC-Opr-070551	Ochotona princeps	69.01	0.00e+00	1290.00
IUUC-Ont-072035	Oreochromis niloticus	55.47	0.00e+00	1851.00
IUUC-Ocu-074930	Oryctolagus cuniculus	85.15	0.00e+00	2934.00
IUUC-Oin-079343	Oryza indica	42.00	8.00e-13	70.50
IUUC-Osa-086106	Oryza sativa	43.00	4.00e-13	70.10
IUUC-Ola-086683	Oryzias latipes	54.15	0.00e+00	1791.00
IUUC-Oar-089557	Ovis aries	89.98	0.00e+00	3112.00
IUUC-Ptr-091366	Pan troglodytes	89.55	0.00e+00	3127.00
IUUC-Pan-092184	Papio anubis	90.52	0.00e+00	3106.00
IUUC-Psi-093720	Pelodiscus sinensis	76.52	0.00e+00	2572.00
IUUC-Pfo-097124	Poecilia formosa	54.76	0.00e+00	1824.00
IUUC-Pab-098586	Pongo abelii	91.73	0.00e+00	3156.00
IUUC-Pop-099184	Populus trichocarpa	44.21	1.00e-13	70.90
IUUC-Pca-100673	Procavia capensis	81.62	0.00e+00	1649.00
IUUC-Pva-102724	Pteropus vampyrus	84.10	0.00e+00	2872.00
IUUC-Pte-104174	Pyrenophora teres	23.33	9.00e-40	160.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	22.72	1.00e-38	156.00
IUUC-Rno-105474	Rattus norvegicus	84.96	0.00e+00	2191.00
IUUC-Sha-106993	Sarcophilus harrisii	79.32	0.00e+00	2771.00
IUUC-Ssl-108638	Sclerotinia sclerotiorum	25.64	3.80e-02	32.30
IUUC-Sar-113447	Sorex araneus	86.25	0.00e+00	2072.00
IUUC-Ssc-115768	Sus scrofa	87.11	0.00e+00	2795.00
IUUC-Tgu-116949	Taeniopygia guttata	70.17	0.00e+00	2351.00
IUUC-Tru-117782	Takifugu rubripes	54.71	0.00e+00	1826.00
IUUC-Tsy-119177	Tarsius syrichta	79.08	0.00e+00	2082.00
IUUC-Tni-120884	Tetraodon nigroviridis	50.62	0.00e+00	1652.00
IUUC-Tbe-128088	Tupaia belangeri	85.51	0.00e+00	820.00
IUUC-Ttr-129062	Tursiops truncatus	84.95	0.00e+00	2891.00
IUUC-Vpa-130578	Vicugna pacos	83.04	0.00e+00	2776.00
IUUC-Vvi-130900	Vitis vinifera	43.75	1.00e-12	67.40
IUUC-Xtr-132244	Xenopus tropicalis	58.10	0.00e+00	1964.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence