iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010117.1	ENSSHAT00000011880.1	ENSSHAP00000011784.1
ENSSHAG00000010117.1	ENSSHAT00000011881.1	ENSSHAP00000011785.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.60e-07	29.9	1104	1207
E3 activity/N-recognin/N-domain	1.20e-34	118.4	230	306
E3 activity/N-recognin/UBR-box	4.60e-31	107.3	102	172

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf.............................................kdgplvlpCgHvfhadClqkw............. 29
           C++C+e+                                               +g+++++CgHv+ha C+qk+             
   Q: 1104 CILCQEEQevrlenaamvlsacvqkssaltqqrgkplelsgeitdplfmdpnlACGTHTGSCGHVMHAICWQKYfeaiqinsrqrlh 1190
           88886655444443333333333333333333333333333333333333333447999***************9999999999999 PP
   S: 30   pglknssskefrCPlCr 46
           +   +++++e +CPlC+
   Q: 1191 VEFFDLENGEYLCPLCK 1207
           999999999999****6 PP

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslqkAl +e+ ea++++t+idkeGRravk G    c eak++i+ +se+++q+pL+Vev
   Q: 230  YYCVLFNDEHHSYDHVIYSLQKALKCELTEAQLHTTAIDKEGRRAVKLGPSVHCREAKENIKFHSENVSQHPLHVEV 306
           9**************************************************************************97 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk+get+y+Cr+C++d+t+vlC++Cf+++vHk+H+yk+++s+gggfCdCGdteAw++g++C +++
   Q: 102  QLCGKVFKSGETTYSCRDCAIDPTCVLCMNCFQNSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCTNHE 172
           68******************************************************************996 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MEDLGLWEAD RTGDRTGIPG SESPPSAQEL ATWWHQQVDF HSAFLYYLAQ TVPDIYFDEI 60
DPELEKQEEV AQLMILTPLE WYLFKEDPAI SLEKLKQSGA FQLCGKVFKS GETTYSCRDC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGACC TCGGACTCTG GGAGGCGGAC CGGACTGGAG ACCGAACTGG CATTCCCGGG 60
AGCGAGTCCC CGCCGAGTGC TCAGGAACTT GCCACGGTGA GAGGCTTTTT CATGGATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

shr:100925300

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	80.85	0.00e+00	2855.00
IUUC-Apl-004160	Anas platyrhynchos	77.76	0.00e+00	2724.00
IUUC-Aca-004982	Anolis carolinensis	75.00	0.00e+00	2638.00
IUUC-Ago-007752	Ashbya gossypii	27.08	3.00e-25	111.00
IUUC-Acl-008055	Aspergillus clavatus	23.55	2.00e-47	185.00
IUUC-Ate-010550	Aspergillus terreus	23.98	2.00e-49	192.00
IUUC-Ame-011231	Astyanax mexicanus	57.48	0.00e+00	1903.00
IUUC-Bgr-011999	Blumeria graminis	22.93	1.00e-46	182.00
IUUC-Bta-012347	Bos taurus	80.85	0.00e+00	2856.00
IUUC-Bci-013834	Botrytis cinerea	23.73	3.00e-47	184.00
IUUC-Cja-018911	Callithrix jacchus	78.31	0.00e+00	2764.00
IUUC-Cfa-020991	Canis familiaris	81.66	0.00e+00	2887.00
IUUC-Cpo-021448	Cavia porcellus	79.66	0.00e+00	2840.00
IUUC-Csa-024255	Chlorocebus sabaeus	81.13	0.00e+00	2367.00
IUUC-Cho-024550	Choloepus hoffmanni	63.08	0.00e+00	2107.00
IUUC-Cne-026823	Cryptococcus neoformans	24.10	2.00e-41	165.00
IUUC-Dno-029427	Dasypus novemcinctus	79.69	0.00e+00	2767.00
IUUC-Dor-031073	Dipodomys ordii	74.40	0.00e+00	1206.00
IUUC-Ete-032318	Echinops telfairi	65.34	0.00e+00	1078.00
IUUC-Eca-033348	Equus caballus	81.62	0.00e+00	2699.00
IUUC-Eeu-034664	Erinaceus europaeus	74.20	0.00e+00	2594.00
IUUC-Fca-035604	Felis catus	77.47	0.00e+00	1332.00
IUUC-Fal-037333	Ficedula albicollis	78.76	0.00e+00	2716.00
IUUC-Gmo-039363	Gadus morhua	55.94	0.00e+00	1646.00
IUUC-Gga-040486	Gallus gallus	76.92	0.00e+00	2657.00
IUUC-Gac-041985	Gasterosteus aculeatus	56.47	0.00e+00	1723.00
IUUC-Ggo-044704	Gorilla gorilla	76.01	0.00e+00	2250.00
IUUC-Hsa-046753	Homo sapiens	81.32	0.00e+00	2885.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	81.58	0.00e+00	2874.00
IUUC-Lch-049904	Latimeria chalumnae	62.58	0.00e+00	2141.00
IUUC-Loc-052624	Lepisosteus oculatus	61.19	0.00e+00	2061.00
IUUC-Laf-053857	Loxodonta africana	79.25	0.00e+00	2799.00
IUUC-Mcc-054873	Macaca mulatta	81.26	0.00e+00	2846.00
IUUC-Meu-056858	Macropus eugenii	77.15	0.00e+00	1215.00
IUUC-Mga-059917	Meleagris gallopavo	77.88	0.00e+00	2769.00
IUUC-Mmr-061128	Microcebus murinus	78.09	0.00e+00	2707.00
IUUC-Mdo-062306	Monodelphis domestica	95.37	0.00e+00	3306.00
IUUC-Mmu-063389	Mus musculus	80.24	0.00e+00	2853.00
IUUC-Mpu-065983	Mustela putorius furo	81.48	0.00e+00	2904.00
IUUC-Mlu-068013	Myotis lucifugus	78.36	0.00e+00	2797.00
IUUC-Nle-070031	Nomascus leucogenys	81.47	0.00e+00	2888.00
IUUC-Opr-070551	Ochotona princeps	60.78	0.00e+00	1149.00
IUUC-Ont-072035	Oreochromis niloticus	57.76	0.00e+00	1966.00
IUUC-Ocu-074930	Oryctolagus cuniculus	77.65	0.00e+00	2725.00
IUUC-Osa-086106	Oryza sativa	43.00	3.00e-14	73.60
IUUC-Ola-086683	Oryzias latipes	57.27	0.00e+00	1898.00
IUUC-Oga-088017	Otolemur garnettii	78.81	0.00e+00	2757.00
IUUC-Oar-089557	Ovis aries	80.66	0.00e+00	2857.00
IUUC-Ptr-091366	Pan troglodytes	80.29	0.00e+00	2858.00
IUUC-Pan-092184	Papio anubis	81.26	0.00e+00	2847.00
IUUC-Psi-093720	Pelodiscus sinensis	79.53	0.00e+00	2708.00
IUUC-Pma-094152	Petromyzon marinus	39.98	3.00e-147	515.00
IUUC-Pfo-097124	Poecilia formosa	57.12	0.00e+00	1912.00
IUUC-Pab-098586	Pongo abelii	81.49	0.00e+00	2886.00
IUUC-Pop-099184	Populus trichocarpa	45.26	3.00e-15	75.90
IUUC-Pca-100673	Procavia capensis	74.10	0.00e+00	1496.00
IUUC-Pva-102724	Pteropus vampyrus	75.47	0.00e+00	2618.00
IUUC-Pte-104174	Pyrenophora teres	23.72	4.00e-48	187.00
IUUC-Rno-105474	Rattus norvegicus	77.67	0.00e+00	2043.00
IUUC-Sar-113447	Sorex araneus	76.39	0.00e+00	1880.00
IUUC-Sre-115045	Sporisorium reilianum	24.91	2.00e-47	185.00
IUUC-Ssc-115768	Sus scrofa	78.03	0.00e+00	2573.00
IUUC-Tgu-116949	Taeniopygia guttata	73.53	0.00e+00	2492.00
IUUC-Tru-117782	Takifugu rubripes	56.80	0.00e+00	1912.00
IUUC-Tsy-119177	Tarsius syrichta	73.13	0.00e+00	1974.00
IUUC-Tni-120884	Tetraodon nigroviridis	53.33	0.00e+00	1734.00
IUUC-Tre-122137	Trichoderma reesei	25.96	9.00e-61	229.00
IUUC-Tbe-128088	Tupaia belangeri	72.60	0.00e+00	1125.00
IUUC-Ttr-129062	Tursiops truncatus	75.98	0.00e+00	2660.00
IUUC-Vpa-130578	Vicugna pacos	73.60	0.00e+00	2562.00
IUUC-Vvi-130900	Vitis vinifera	44.79	4.00e-14	72.00
IUUC-Xtr-132244	Xenopus tropicalis	60.81	0.00e+00	2107.00
IUUC-Xma-134112	Xiphophorus maculatus	57.07	0.00e+00	1913.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence