iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021425

Ensembl Protein ID

ENSCPOP00000018515.1

UniProt Accession

H0W6B1; H0W6B1_CAVPO

Genbank Protein ID

ENSCPOP00000018515

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02055595

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000026534.1	ENSCPOT00000027629.1	ENSCPOP00000018515.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	79.50	2.00e-173	606.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	79.50	2.00e-173	606.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	79.60	2.00e-180	629.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	79.15	4.00e-179	624.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MASLTVKAYL LGKEGAAREI RRFSFRFSLD SQVEAEAAAA GPGACEQLLC RVAALFALHP 60
GGFQAHYRDE DGDLVAFSSD EELMMAMSYV KDDIFRIYIK EKKEYRREHR PHCAQEAPGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCGC TTACTGTGAA GGCCTATCTG CTGGGCAAGG AGGGCGCGGC GCGCGAGATC 60
CGACGCTTCA GCTTCCGCTT TAGCCTGGAC TCTCAGGTGG AGGCTGAGGC GGCGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	80.00	9.00e-147	512.00
IUUC-Apl-003897	Anas platyrhynchos	56.34	2.00e-109	389.00
IUUC-Aca-004699	Anolis carolinensis	47.87	3.00e-92	332.00
IUUC-Ame-010982	Astyanax mexicanus	44.51	3.00e-58	219.00
IUUC-Bta-012634	Bos taurus	79.10	0.00e+00	638.00
IUUC-Cel-018540	Caenorhabditis elegans	42.86	9.00e-11	62.00
IUUC-Cja-019684	Callithrix jacchus	80.22	5.00e-176	610.00
IUUC-Cfa-020573	Canis familiaris	74.85	2.00e-112	398.00
IUUC-Csa-023968	Chlorocebus sabaeus	80.00	4.00e-173	600.00
IUUC-Cho-024596	Choloepus hoffmanni	71.61	3.00e-37	149.00
IUUC-Cin-025557	Ciona intestinalis	29.00	2.00e-13	69.30
IUUC-Csv-025974	Ciona savignyi	26.13	3.00e-14	72.40
IUUC-Cne-027045	Cryptococcus neoformans	44.44	1.00e-09	59.30
IUUC-Dre-028621	Danio rerio	44.38	3.00e-89	322.00
IUUC-Dno-029060	Dasypus novemcinctus	76.46	2.00e-176	611.00
IUUC-Dor-030547	Dipodomys ordii	76.45	9.00e-116	410.00
IUUC-Ete-033201	Echinops telfairi	72.15	3.00e-140	491.00
IUUC-Eca-033456	Equus caballus	80.88	2.00e-165	575.00
IUUC-Eeu-035157	Erinaceus europaeus	76.19	5.00e-147	513.00
IUUC-Fca-035403	Felis catus	79.24	5.00e-174	603.00
IUUC-Fal-036798	Ficedula albicollis	55.77	3.00e-123	434.00
IUUC-Gmo-039619	Gadus morhua	39.78	8.00e-43	167.00
IUUC-Gga-040137	Gallus gallus	56.93	2.00e-123	435.00
IUUC-Gac-042410	Gasterosteus aculeatus	43.49	9.00e-86	310.00
IUUC-Ggo-044690	Gorilla gorilla	80.67	5.00e-174	603.00
IUUC-Hsa-046390	Homo sapiens	80.45	7.00e-173	600.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	81.80	0.00e+00	650.00
IUUC-Lch-049658	Latimeria chalumnae	47.16	1.00e-103	370.00
IUUC-Loc-052589	Lepisosteus oculatus	45.94	6.00e-97	347.00
IUUC-Laf-053746	Loxodonta africana	71.36	5.00e-156	543.00
IUUC-Mcc-055635	Macaca mulatta	79.55	2.00e-173	601.00
IUUC-Meu-056528	Macropus eugenii	50.25	2.00e-95	342.00
IUUC-Mga-059458	Meleagris gallopavo	59.05	1.00e-110	392.00
IUUC-Mmr-061539	Microcebus murinus	75.70	9.00e-118	416.00
IUUC-Mdo-063083	Monodelphis domestica	60.35	8.00e-135	473.00
IUUC-Mmu-063589	Mus musculus	78.25	4.00e-180	624.00
IUUC-Mpu-065727	Mustela putorius furo	79.30	2.00e-156	545.00
IUUC-Mlu-067026	Myotis lucifugus	79.52	5.00e-160	556.00
IUUC-Nle-069356	Nomascus leucogenys	59.20	8.00e-97	347.00
IUUC-Opr-071091	Ochotona princeps	62.01	1.00e-84	306.00
IUUC-Ont-071864	Oreochromis niloticus	45.23	1.00e-94	339.00
IUUC-Oan-073308	Ornithorhynchus anatinus	57.02	4.00e-117	414.00
IUUC-Ocu-074110	Oryctolagus cuniculus	81.67	0.00e+00	629.00
IUUC-Ola-086944	Oryzias latipes	42.79	2.00e-34	138.00
IUUC-Oga-088869	Otolemur garnettii	79.46	0.00e+00	628.00
IUUC-Oar-089857	Ovis aries	80.85	1.00e-163	569.00
IUUC-Ptr-091640	Pan troglodytes	80.67	5.00e-174	603.00
IUUC-Pan-092831	Papio anubis	80.58	1.00e-175	609.00
IUUC-Psi-093925	Pelodiscus sinensis	54.22	4.00e-117	414.00
IUUC-Pma-094576	Petromyzon marinus	31.54	1.00e-28	120.00
IUUC-Pfo-097297	Poecilia formosa	42.64	3.00e-82	299.00
IUUC-Pab-098725	Pongo abelii	72.30	7.00e-155	540.00
IUUC-Pca-101106	Procavia capensis	78.65	1.00e-169	588.00
IUUC-Pva-102710	Pteropus vampyrus	76.14	6.00e-150	523.00
IUUC-Rno-105539	Rattus norvegicus	78.92	0.00e+00	638.00
IUUC-Sha-107469	Sarcophilus harrisii	55.58	6.00e-112	397.00
IUUC-Ssc-115526	Sus scrofa	81.80	6.00e-179	620.00
IUUC-Tgu-117194	Taeniopygia guttata	59.48	8.00e-110	390.00
IUUC-Tru-117896	Takifugu rubripes	45.45	1.00e-91	330.00
IUUC-Tni-119943	Tetraodon nigroviridis	44.67	2.00e-82	299.00
IUUC-Ttr-128676	Tursiops truncatus	78.88	5.00e-180	623.00
IUUC-Vda-129812	Verticillium dahliae	46.34	3.00e-06	47.00
IUUC-Vpa-130319	Vicugna pacos	88.89	5.00e-51	194.00
IUUC-Xtr-132907	Xenopus tropicalis	51.19	4.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence