iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002325

Ensembl Protein ID

ENSAMEP00000006849.1

UniProt Accession

G1LIU5; G1LIU5_AILME

Genbank Protein ID

ENSAMEP00000006849

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01153881

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000006490.1	ENSAMET00000007135.1	ENSAMEP00000006849.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.40e-09	35.2	5	41
ULD/UDP/UFD/UBX	1.90e-20	73.3	208	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 6    kleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 5    ALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 41
           6999******************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ + ++dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 208  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGDQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 289
           578*****************************************************************************98 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

GGLTALESLI EMGFPRGRAE KALALTGNQG IEAAMDWLME HEDDPDVDEP LATPLGHVLG 60
REPTSSEQGG PEGTGSTAGE GKPVLSEEER QEQTKRMLEL VAQKQREREE REEREALERE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGCTGA CGGCTCTGGA GAGTCTCATC GAGATGGGCT TCCCCAGGGG ACGCGCGTAA 60
GGCAGCCCCC CAAACCCTGG CCCGCGGAGA TCGCGGACCT GTCTGGCCTT TCCCCCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004329	Anolis carolinensis	73.10	4.00e-50	190.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	1.00e-11	64.30
IUUC-Ath-006887	Arabidopsis thaliana	40.48	2.00e-11	63.50
IUUC-Ame-011399	Astyanax mexicanus	52.96	5.00e-64	237.00
IUUC-Bta-013151	Bos taurus	94.54	6.00e-124	436.00
IUUC-Bol-016537	Brassica oleracea	50.91	2.00e-11	63.50
IUUC-Bra-017212	Brassica rapa	42.86	7.00e-11	63.20
IUUC-Cel-018300	Caenorhabditis elegans	35.11	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	92.88	5.00e-100	357.00
IUUC-Cfa-020997	Canis familiaris	96.07	4.00e-92	330.00
IUUC-Cpo-021736	Cavia porcellus	80.27	2.00e-81	295.00
IUUC-Csa-024040	Chlorocebus sabaeus	91.84	4.00e-100	357.00
IUUC-Cho-024543	Choloepus hoffmanni	96.53	8.00e-72	263.00
IUUC-Cin-025719	Ciona intestinalis	41.36	5.00e-41	160.00
IUUC-Csv-025854	Ciona savignyi	39.32	6.00e-39	154.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	3.00e-08	53.10
IUUC-Dre-027745	Danio rerio	52.20	1.00e-60	226.00
IUUC-Dno-029598	Dasypus novemcinctus	90.78	6.00e-103	367.00
IUUC-Dor-030917	Dipodomys ordii	77.94	3.00e-86	311.00
IUUC-Dme-032055	Drosophila melanogaster	42.94	1.00e-24	107.00
IUUC-Ete-032960	Echinops telfairi	76.98	1.00e-77	283.00
IUUC-Eca-034294	Equus caballus	95.22	6.00e-113	400.00
IUUC-Eeu-034906	Erinaceus europaeus	91.84	1.00e-105	376.00
IUUC-Fca-035653	Felis catus	97.86	1.00e-98	352.00
IUUC-Gmo-038755	Gadus morhua	51.29	2.00e-56	212.00
IUUC-Gac-042481	Gasterosteus aculeatus	53.75	4.00e-57	214.00
IUUC-Ggo-044821	Gorilla gorilla	90.75	2.00e-93	335.00
IUUC-Hsa-046797	Homo sapiens	91.16	9.00e-102	362.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	92.52	1.00e-111	395.00
IUUC-Lch-049508	Latimeria chalumnae	52.92	3.00e-56	211.00
IUUC-Laf-053932	Loxodonta africana	95.92	9.00e-131	459.00
IUUC-Mcc-055300	Macaca mulatta	92.18	4.00e-100	357.00
IUUC-Mtr-058774	Medicago truncatula	50.00	7.00e-10	57.80
IUUC-Mvi-060245	Microbotryum violaceum	40.48	1.00e-11	63.90
IUUC-Mmr-060979	Microcebus murinus	91.50	6.00e-107	380.00
IUUC-Mdo-062299	Monodelphis domestica	85.87	3.00e-97	347.00
IUUC-Mmu-063212	Mus musculus	93.88	6.00e-117	413.00
IUUC-Mac-065377	Musa acuminata	51.11	1.00e-11	60.80
IUUC-Mpu-066540	Mustela putorius furo	98.63	9.00e-117	412.00
IUUC-Mlu-067589	Myotis lucifugus	95.56	5.00e-110	390.00
IUUC-Nle-069045	Nomascus leucogenys	91.60	2.00e-74	272.00
IUUC-Opr-070772	Ochotona princeps	89.29	6.00e-88	317.00
IUUC-Ont-072006	Oreochromis niloticus	53.05	1.00e-57	216.00
IUUC-Oan-073244	Ornithorhynchus anatinus	62.86	9.00e-48	183.00
IUUC-Ocu-074333	Oryctolagus cuniculus	89.80	8.00e-103	366.00
IUUC-Oba-075451	Oryza barthii	49.06	5.00e-11	62.40
IUUC-Obr-076923	Oryza brachyantha	55.10	1.00e-11	64.30
IUUC-Ogl-077259	Oryza glaberrima	37.84	5.00e-10	58.90
IUUC-Ogu-078589	Oryza glumaepatula	49.06	5.00e-11	62.40
IUUC-Oin-079151	Oryza indica	49.06	4.00e-11	62.40
IUUC-Ome-081253	Oryza meridionalis	49.06	4.00e-11	62.40
IUUC-Oni-082110	Oryza nivara	37.84	1.00e-10	60.10
IUUC-Opu-083336	Oryza punctata	49.06	5.00e-11	62.00
IUUC-Oru-085235	Oryza rufipogon	49.06	5.00e-11	62.40
IUUC-Osa-085611	Oryza sativa	49.06	5.00e-11	62.40
IUUC-Ola-086781	Oryzias latipes	52.94	1.00e-54	206.00
IUUC-Oga-088429	Otolemur garnettii	91.50	4.00e-102	363.00
IUUC-Oar-089885	Ovis aries	93.86	3.00e-123	434.00
IUUC-Ptr-091315	Pan troglodytes	90.71	2.00e-93	335.00
IUUC-Pan-092885	Papio anubis	91.84	4.00e-100	357.00
IUUC-Psi-093299	Pelodiscus sinensis	72.50	1.00e-66	245.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	59.70
IUUC-Pfo-096188	Poecilia formosa	53.62	8.00e-54	203.00
IUUC-Pab-097881	Pongo abelii	85.71	2.00e-98	352.00
IUUC-Pop-098863	Populus trichocarpa	36.87	3.00e-12	66.20
IUUC-Pca-100977	Procavia capensis	91.90	1.00e-103	369.00
IUUC-Ppe-101243	Prunus persica	47.06	4.00e-10	58.50
IUUC-Pva-102169	Pteropus vampyrus	94.31	4.00e-98	350.00
IUUC-Rno-105459	Rattus norvegicus	93.20	2.00e-116	411.00
IUUC-Sha-107526	Sarcophilus harrisii	87.67	6.00e-96	343.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	26.67	3.00e-06	46.20
IUUC-Sit-110434	Setaria italica	32.07	1.00e-09	57.40
IUUC-Sar-112945	Sorex araneus	93.51	3.00e-71	261.00
IUUC-Sbi-114159	Sorghum bicolor	31.15	8.00e-11	60.80
IUUC-Ssc-116114	Sus scrofa	92.52	6.00e-100	357.00
IUUC-Tru-117839	Takifugu rubripes	52.61	8.00e-56	210.00
IUUC-Tsy-118813	Tarsius syrichta	72.24	3.00e-96	345.00
IUUC-Tni-120504	Tetraodon nigroviridis	58.16	5.00e-57	214.00
IUUC-Tbe-128034	Tupaia belangeri	92.17	8.00e-103	366.00
IUUC-Ttr-128468	Tursiops truncatus	87.71	1.00e-100	359.00
IUUC-Uma-129569	Ustilago maydis	33.33	1.00e-04	40.40
IUUC-Vpa-130179	Vicugna pacos	90.04	4.00e-79	287.00
IUUC-Xtr-132119	Xenopus tropicalis	62.93	4.00e-68	251.00
IUUC-Xma-134067	Xiphophorus maculatus	52.79	5.00e-54	204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence