iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000018804.4	ENSCAFT00000046445.2	ENSCAFP00000041869.1
ENSCAFG00000018804.4	ENSCAFT00000029847.3	ENSCAFP00000027739.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.50e-86	288.9	81	784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDEANQKDKGsckedslasyELICSLQSLIISVeqlqasfLlnpek 169
           6************************************99999999999999999999******99999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  ek ++kee+++        +    
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvvelstkieEKPHQKEEMSG--------Insie 250
           88888*****************************************555555666665555544444444444444........15555 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 251  mdnlrpsedykeklpkgngkrksdtefgnmkkkvkvskehqsleenqrqtrskrkatgdtleipskiipkcvsenesarpsqkksrvki 339
           5666************************************************************************************* PP
   S: 130  ..........................................................................aeekkkkknk..... 139
                                                                                           +k+      
   Q: 340  nwlkpatkqpsilskfcslgkittnqgskeqlkeneydleedlgkcendnttngcelespgdnvkpvnvnevkpI-----NKGAeqigf 423
           ******************************************************************999544443.....444455566 PP
   S: 140  slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkk 214
           +l+++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c+++
   Q: 424  ELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDKYFCENCHHY 512
           *****************************************99998******************************************* PP
   S: 215  qeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYva 297
           +eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a
   Q: 513  TEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTA 596
           **********************************************************99.....678********************* PP
   S: 298  yvkn..................................................................................... 301
            vk                                                                                      
   Q: 597  SVKVtdlnsleldkgnfvidqmceigkpeplneeeargvvenydddevsirvsgntqpskvlnkknveaigllggqkskadyelynkas 685
           ***************************************************************************************** PP
   S: 302  .........................................................ekgkWllfdDskVtevkeeevleetg...... 327
                                                                     +gkWllfdDs+V++++e+++l++ +      
   Q: 686  npdkvastafaenrnsetnntngthefdtnkessdqtginfsgfenkiscvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstspt 774
           *********************9999999999999999999999988888888877766999*******************888****** PP
   S: 328  staYvlfYkr 337
           st+Y+lfYk+
   Q: 775  STPYLLFYKK 784
           ********97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQENEEKAS EYRGSEIDQV 60
VPAAQSSPVH CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNIISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATGATTGA TTACAACATC CTTGTATAAA TTAATTCTTG TAAACTCCTT GGGATTTGAA 60
GAGAAAATGC CTGGTGTCAT ACCTAGTGAA AGTAATGGGC TTTCAAGAGG TAGCCCGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cfa:479549

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	96.69	0.00e+00	1467.00
IUUC-Apl-004204	Anas platyrhynchos	73.82	0.00e+00	955.00
IUUC-Aca-004637	Anolis carolinensis	66.37	0.00e+00	935.00
IUUC-Ame-011718	Astyanax mexicanus	48.43	2.00e-172	599.00
IUUC-Bta-012552	Bos taurus	92.74	0.00e+00	1415.00
IUUC-Cja-019588	Callithrix jacchus	94.27	0.00e+00	1471.00
IUUC-Cpo-021551	Cavia porcellus	83.82	0.00e+00	1275.00
IUUC-Csa-024186	Chlorocebus sabaeus	94.52	0.00e+00	1478.00
IUUC-Cho-024739	Choloepus hoffmanni	84.27	0.00e+00	764.00
IUUC-Dre-028184	Danio rerio	49.21	9.00e-176	610.00
IUUC-Dno-029669	Dasypus novemcinctus	90.36	0.00e+00	1392.00
IUUC-Dor-030168	Dipodomys ordii	86.42	0.00e+00	1251.00
IUUC-Dme-031732	Drosophila melanogaster	28.77	6.00e-18	86.70
IUUC-Ete-032825	Echinops telfairi	86.81	0.00e+00	959.00
IUUC-Eca-033595	Equus caballus	93.27	0.00e+00	1355.00
IUUC-Eeu-034877	Erinaceus europaeus	81.34	3.00e-162	565.00
IUUC-Fca-035381	Felis catus	95.38	0.00e+00	1031.00
IUUC-Fal-037592	Ficedula albicollis	69.64	0.00e+00	980.00
IUUC-Gmo-039680	Gadus morhua	45.30	2.00e-153	536.00
IUUC-Gga-041196	Gallus gallus	72.91	0.00e+00	1077.00
IUUC-Gac-042292	Gasterosteus aculeatus	50.00	2.00e-145	509.00
IUUC-Ggo-044671	Gorilla gorilla	94.78	0.00e+00	1477.00
IUUC-Hsa-047020	Homo sapiens	94.39	0.00e+00	1471.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	85.62	0.00e+00	1273.00
IUUC-Lch-050543	Latimeria chalumnae	57.89	0.00e+00	704.00
IUUC-Loc-052338	Lepisosteus oculatus	53.16	0.00e+00	702.00
IUUC-Laf-053707	Loxodonta africana	91.00	0.00e+00	1422.00
IUUC-Mcc-055885	Macaca mulatta	94.78	0.00e+00	1483.00
IUUC-Meu-056573	Macropus eugenii	67.34	0.00e+00	958.00
IUUC-Mga-059346	Meleagris gallopavo	73.65	0.00e+00	1030.00
IUUC-Mmr-061612	Microcebus murinus	93.50	0.00e+00	1391.00
IUUC-Mdo-062887	Monodelphis domestica	72.49	0.00e+00	1051.00
IUUC-Mmu-064044	Mus musculus	88.17	0.00e+00	1364.00
IUUC-Mpu-066847	Mustela putorius furo	97.83	0.00e+00	1490.00
IUUC-Mlu-067684	Myotis lucifugus	91.61	0.00e+00	1425.00
IUUC-Nle-070057	Nomascus leucogenys	94.52	0.00e+00	1478.00
IUUC-Opr-070463	Ochotona princeps	83.42	0.00e+00	1248.00
IUUC-Ont-071975	Oreochromis niloticus	46.42	3.00e-153	535.00
IUUC-Oan-073062	Ornithorhynchus anatinus	87.76	2.00e-47	181.00
IUUC-Ocu-074840	Oryctolagus cuniculus	93.12	0.00e+00	1432.00
IUUC-Ola-087088	Oryzias latipes	47.14	3.00e-174	605.00
IUUC-Oga-088472	Otolemur garnettii	92.10	0.00e+00	1415.00
IUUC-Oar-089498	Ovis aries	92.74	0.00e+00	1417.00
IUUC-Ptr-091395	Pan troglodytes	94.52	0.00e+00	1473.00
IUUC-Pan-092462	Papio anubis	94.90	0.00e+00	1484.00
IUUC-Psi-093583	Pelodiscus sinensis	73.11	0.00e+00	929.00
IUUC-Pma-094644	Petromyzon marinus	36.36	1.00e-28	119.00
IUUC-Pfo-096314	Poecilia formosa	46.64	4.00e-167	581.00
IUUC-Pab-098568	Pongo abelii	95.03	0.00e+00	1484.00
IUUC-Pca-100948	Procavia capensis	81.96	0.00e+00	1253.00
IUUC-Pva-102853	Pteropus vampyrus	93.11	0.00e+00	1430.00
IUUC-Rno-105573	Rattus norvegicus	89.17	0.00e+00	1354.00
IUUC-Sha-107495	Sarcophilus harrisii	71.73	0.00e+00	889.00
IUUC-Sar-113545	Sorex araneus	77.55	0.00e+00	1106.00
IUUC-Ssc-115962	Sus scrofa	93.92	0.00e+00	1456.00
IUUC-Tgu-116731	Taeniopygia guttata	70.71	0.00e+00	998.00
IUUC-Tru-117893	Takifugu rubripes	46.55	3.00e-158	551.00
IUUC-Tsy-119644	Tarsius syrichta	84.06	0.00e+00	1257.00
IUUC-Tni-119819	Tetraodon nigroviridis	44.31	3.00e-170	592.00
IUUC-Tbe-127272	Tupaia belangeri	88.61	0.00e+00	1257.00
IUUC-Ttr-128404	Tursiops truncatus	94.39	0.00e+00	1454.00
IUUC-Vpa-130205	Vicugna pacos	93.11	0.00e+00	1438.00
IUUC-Xtr-132613	Xenopus tropicalis	55.93	0.00e+00	746.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence