iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000162843.17	ENST00000414635.5	ENSP00000406656.1
ENSG00000162843.17	ENST00000472717.6	ENSP00000431729.2
ENSG00000162843.17	ENST00000425826.2	ENSP00000406342.2
ENSG00000162843.17	ENST00000437684.6	ENSP00000402446.3
ENSG00000162843.17	ENST00000366552.6	ENSP00000355510.2

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	CircNet	microRNA
TRANSFAC	TargetScan	RepTar	miRNAMap
SomamiR	miRcode	RAID2
Disease-associated Variation
GWASdb	GWAS Central
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-20	72.2	503	532

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sdtllvsGsdDgtikvWDlrtg 33
           vt+ a   s+ l+++G+++gt+++WD+ +g
   Q: 503  VTSAAVdeSGFLFATGAYNGTVRIWDFGSG 532
           6666665443579*************8666 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MDIRKEKRLN MALQMSNFKK ALNRFEKLVE QTAAQKRDER AGLFIHKEDA IGYDKFYASV 60
QKLFGPDVKN QDVKRFYRKL CNNTDASADW CEIFGYFSSE EDPIASQLDE ENLVFFVSRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCAGACCTA AATCAGCTTT CCTCCCTGCT AACATCCTAG TGGCAACTCT TACTCCTACC 60
CGCACTATGG GATTTTAAGA TCAAAGGAAT TAGACCTAGG GCAAAAACTG AGACAGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

hsa:128025

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001243	Ailuropoda melanoleuca	80.87	0.00e+00	1798.00
IUUC-Apl-003630	Anas platyrhynchos	44.99	2.00e-97	350.00
IUUC-Aca-005117	Anolis carolinensis	54.52	2.00e-94	339.00
IUUC-Bta-013033	Bos taurus	85.13	0.00e+00	1878.00
IUUC-Cja-019126	Callithrix jacchus	90.66	0.00e+00	1991.00
IUUC-Cfa-020151	Canis familiaris	84.70	0.00e+00	1110.00
IUUC-Csa-023945	Chlorocebus sabaeus	96.21	0.00e+00	2100.00
IUUC-Dno-029342	Dasypus novemcinctus	79.10	0.00e+00	1757.00
IUUC-Dor-030882	Dipodomys ordii	70.13	0.00e+00	915.00
IUUC-Ete-032995	Echinops telfairi	66.19	0.00e+00	653.00
IUUC-Eca-033883	Equus caballus	85.03	0.00e+00	1919.00
IUUC-Eeu-035145	Erinaceus europaeus	65.13	0.00e+00	906.00
IUUC-Fca-036002	Felis catus	85.44	0.00e+00	1434.00
IUUC-Fal-037351	Ficedula albicollis	47.10	0.00e+00	879.00
IUUC-Gga-041212	Gallus gallus	55.77	0.00e+00	756.00
IUUC-Ggo-045447	Gorilla gorilla	97.74	0.00e+00	807.00
IUUC-Itr-049002	Ictidomys tridecemlineatus	67.18	0.00e+00	1358.00
IUUC-Lch-050538	Latimeria chalumnae	43.09	0.00e+00	653.00
IUUC-Laf-053922	Loxodonta africana	82.23	0.00e+00	1806.00
IUUC-Mcc-055613	Macaca mulatta	96.02	0.00e+00	2098.00
IUUC-Meu-056669	Macropus eugenii	56.70	0.00e+00	850.00
IUUC-Mga-060077	Meleagris gallopavo	44.89	0.00e+00	816.00
IUUC-Mmr-060964	Microcebus murinus	85.34	0.00e+00	1826.00
IUUC-Mdo-062706	Monodelphis domestica	67.01	0.00e+00	1509.00
IUUC-Mmu-063879	Mus musculus	80.15	0.00e+00	1779.00
IUUC-Mpu-066204	Mustela putorius furo	80.05	0.00e+00	1764.00
IUUC-Mlu-067032	Myotis lucifugus	80.50	0.00e+00	1777.00
IUUC-Nle-069892	Nomascus leucogenys	96.58	0.00e+00	2108.00
IUUC-Opr-070895	Ochotona princeps	75.87	0.00e+00	1363.00
IUUC-Oan-072990	Ornithorhynchus anatinus	70.29	0.00e+00	1002.00
IUUC-Ocu-074260	Oryctolagus cuniculus	77.30	0.00e+00	1688.00
IUUC-Oga-087946	Otolemur garnettii	84.22	0.00e+00	1864.00
IUUC-Oar-090249	Ovis aries	83.44	0.00e+00	1857.00
IUUC-Ptr-090673	Pan troglodytes	98.89	0.00e+00	2159.00
IUUC-Pan-091772	Papio anubis	93.51	0.00e+00	2026.00
IUUC-Psi-094037	Pelodiscus sinensis	56.02	0.00e+00	1169.00
IUUC-Ppa-095538	Physcomitrella patens	21.19	6.00e-15	76.30
IUUC-Pab-097565	Pongo abelii	86.03	0.00e+00	1756.00
IUUC-Pca-100863	Procavia capensis	68.27	0.00e+00	844.00
IUUC-Pva-103108	Pteropus vampyrus	87.39	0.00e+00	1021.00
IUUC-Rno-104936	Rattus norvegicus	79.30	0.00e+00	1757.00
IUUC-Sha-106796	Sarcophilus harrisii	68.31	0.00e+00	1064.00
IUUC-Sar-113154	Sorex araneus	63.49	0.00e+00	645.00
IUUC-Ssc-116065	Sus scrofa	86.38	4.00e-134	470.00
IUUC-Tsy-118831	Tarsius syrichta	81.33	0.00e+00	1694.00
IUUC-Tbe-127575	Tupaia belangeri	67.34	1.00e-149	524.00
IUUC-Ttr-128737	Tursiops truncatus	78.28	0.00e+00	1673.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence