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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046838
UUCD1 version UUC-HoS-01252
Ensembl Protein ID ENSP00000408108.2
UniProt Accession Q9H7D7; A0MNN3; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; WDR26_HUMAN
Genbank Protein ID BAD93124.1; AAH31471.2; AAH34498.1; AAH52301.2; AAH63817.2; AAO67709.1; AAQ74770.1; AAG35477.1; ABK41102.1; BAB14955.1
Protein Name WD repeat-containing protein 26; CUL4- and DDB1-associated WDR protein 2; Myocardial ischemic preconditioning up-regulated protein 2
Genbank Nucleotide ID AB209887; AC099790; BC034498; BC052301; BC063817; AY221751; AY304473; AF130049; EF011612; AK024669
Gene Name WDR26; CDW2; MIP2; PRO0852
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000162923.14 ENST00000414423.6 ENSP00000408108.2
ENSG00000162923.14 ENST00000480676.2 ENSP00000424784.1
ENSG00000162923.14 ENST00000486652.5 ENSP00000422758.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Information
ClinVarGWASdbGWAS Central
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/DCX/DWD WD_repeat 17588513
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-28 99.2 611 642
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWD 29
           gHt  v+c+++    +  +++s+sdDgt+++W 
   Q: 611  GHTRTVNCVSWnpqiP-SMMASASDDGTVRIWG 642
           8**********95554.799************7 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May be involved in MAPK pathways.
 May be involved in MAPK pathways.
Protein Sequence
(Fasta)
MQANGAGGGG GGGGGGGGGG GGGGGQGQTP ELACLSAQNG ESSPSSSSSA GDLAHANGLL 60
PSAPSAASNN SNSLNVNNGV PGGAAAASSA TVAAASATTA ASSSLATPEL GSSLKKKKRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046838|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGTGGAAGT CAGGAAAGGC TCCCCTGAGG AGGTTTGAAA TGAGCTGAGT CTTGAAAGAC 60
TGACTGGCAT CAGACAGGTG AAGAAAAGAC GGGAGAGTGT AGTCAAAGAC TCTCAAGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046838|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR006595--CTLH_C
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50897--CTLH
PS50896--LISH
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00668--CTLH
SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
KEGG hsa:80232
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000905 Aegilops tauschii 38.19 3.00e-94 339.00
IUUC-Aml-001381 Ailuropoda melanoleuca 99.46 0.00e+00 1033.00
IUUC-Atr-003020 Amborella trichopoda 38.43 8.00e-91 327.00
IUUC-Apl-003200 Anas platyrhynchos 95.43 0.00e+00 965.00
IUUC-Aca-005122 Anolis carolinensis 95.03 0.00e+00 995.00
IUUC-Aly-005958 Arabidopsis lyrata 38.52 2.00e-84 306.00
IUUC-Ath-007549 Arabidopsis thaliana 37.43 9.00e-84 304.00
IUUC-Ago-007896 Ashbya gossypii 35.11 5.00e-18 86.70
IUUC-Acl-008259 Aspergillus clavatus 37.75 4.00e-89 322.00
IUUC-Afl-008669 Aspergillus flavus 36.98 8.00e-83 301.00
IUUC-Afu-008972 Aspergillus fumigatus 38.18 7.00e-63 234.00
IUUC-Ani-009455 Aspergillus nidulans 32.97 4.00e-65 243.00
IUUC-Ang-009832 Aspergillus niger 35.89 2.00e-79 290.00
IUUC-Aor-010221 Aspergillus oryzae 38.23 3.00e-86 313.00
IUUC-Ate-010262 Aspergillus terreus 38.79 1.00e-91 331.00
IUUC-Ame-010615 Astyanax mexicanus 89.57 0.00e+00 926.00
IUUC-Bgr-012047 Blumeria graminis 37.71 8.00e-84 305.00
IUUC-Bta-012566 Bos taurus 99.81 0.00e+00 989.00
IUUC-Bci-013589 Botrytis cinerea 35.48 6.00e-78 285.00
IUUC-Bdi-014338 Brachypodium distachyon 37.74 3.00e-94 339.00
IUUC-Bol-015143 Brassica oleracea 36.30 1.00e-79 290.00
IUUC-Bra-017245 Brassica rapa 37.36 4.00e-83 302.00
IUUC-Cel-018613 Caenorhabditis elegans 24.14 1.00e-39 158.00
IUUC-Cja-019082 Callithrix jacchus 100.00 0.00e+00 1039.00
IUUC-Cfa-020788 Canis familiaris 100.00 0.00e+00 991.00
IUUC-Cpo-022453 Cavia porcellus 98.85 0.00e+00 997.00
IUUC-Csa-023815 Chlorocebus sabaeus 96.99 0.00e+00 866.00
IUUC-Cho-024572 Choloepus hoffmanni 86.90 6.00e-156 543.00
IUUC-Cin-025474 Ciona intestinalis 67.88 9.00e-116 409.00
IUUC-Csv-026251 Ciona savignyi 58.43 1.00e-174 605.00
IUUC-Cgl-026607 Colletotrichum gloeosporioides 37.33 3.00e-82 299.00
IUUC-Cne-026805 Cryptococcus neoformans 33.00 2.00e-47 184.00
IUUC-Cme-027218 Cyanidioschyzon merolae 27.36 2.00e-44 174.00
IUUC-Dre-027404 Danio rerio 89.19 0.00e+00 911.00
IUUC-Dno-029089 Dasypus novemcinctus 95.45 0.00e+00 1000.00
IUUC-Dor-030714 Dipodomys ordii 86.92 0.00e+00 720.00
IUUC-Dse-031569 Dothistroma septosporum 33.39 2.00e-74 274.00
IUUC-Dme-032077 Drosophila melanogaster 56.90 2.00e-179 622.00
IUUC-Ete-032986 Echinops telfairi 74.54 7.00e-125 441.00
IUUC-Eca-033943 Equus caballus 99.62 0.00e+00 999.00
IUUC-Eeu-034468 Erinaceus europaeus 69.47 1.00e-123 437.00
IUUC-Fca-036556 Felis catus 94.40 0.00e+00 950.00
IUUC-Fal-036639 Ficedula albicollis 92.93 0.00e+00 1005.00
IUUC-Fox-037720 Fusarium oxysporum 36.87 3.00e-82 299.00
IUUC-Fso-038206 Fusarium solani 35.06 6.00e-80 291.00
IUUC-Gmo-038610 Gadus morhua 88.59 0.00e+00 944.00
IUUC-Ggr-039738 Gaeumannomyces graminis 34.85 2.00e-79 290.00
IUUC-Gga-040577 Gallus gallus 95.07 0.00e+00 1003.00
IUUC-Gac-041352 Gasterosteus aculeatus 89.33 0.00e+00 959.00
IUUC-Gma-043704 Glycine max 37.45 5.00e-84 305.00
IUUC-Ggo-044684 Gorilla gorilla 100.00 0.00e+00 1054.00
IUUC-Hvu-047226 Hordeum vulgare 36.97 1.00e-90 327.00
IUUC-Itr-048020 Ictidomys tridecemlineatus 100.00 0.00e+00 1039.00
IUUC-Kpa-049141 Komagataella pastoris 27.96 2.00e-45 177.00
IUUC-Lch-049848 Latimeria chalumnae 88.56 0.00e+00 784.00
IUUC-Lpe-050963 Leersia perrieri 39.08 3.00e-101 362.00
IUUC-Loc-052708 Lepisosteus oculatus 91.90 0.00e+00 964.00
IUUC-Lma-053156 Leptosphaeria maculans 34.29 4.00e-78 285.00
IUUC-Laf-054153 Loxodonta africana 99.07 0.00e+00 1033.00
IUUC-Mcc-054742 Macaca mulatta 100.00 0.00e+00 1054.00
IUUC-Meu-056633 Macropus eugenii 84.66 3.00e-134 471.00
IUUC-Mor-056939 Magnaporthe oryzae 38.33 9.00e-88 317.00
IUUC-Mpo-057600 Magnaporthe poae 35.03 1.00e-77 285.00
IUUC-Mtr-058724 Medicago truncatula 37.52 9.00e-89 320.00
IUUC-Mla-058912 Melampsora laricipopulina 41.00 1.00e-86 313.00
IUUC-Mga-059811 Meleagris gallopavo 92.46 0.00e+00 857.00
IUUC-Mvi-060274 Microbotryum violaceum 35.14 1.00e-85 311.00
IUUC-Mmr-060823 Microcebus murinus 98.73 0.00e+00 1039.00
IUUC-Mdo-062394 Monodelphis domestica 95.72 0.00e+00 990.00
IUUC-Mmu-063924 Mus musculus 95.10 0.00e+00 1045.00
IUUC-Mac-065563 Musa acuminata 38.77 6.00e-96 345.00
IUUC-Mpu-066858 Mustela putorius furo 95.56 0.00e+00 991.00
IUUC-Mlu-067659 Myotis lucifugus 99.81 0.00e+00 1036.00
IUUC-Nfi-068498 Neosartorya fischeri 38.40 3.00e-89 322.00
IUUC-Ncr-068832 Neurospora crassa 37.55 4.00e-78 285.00
IUUC-Nle-069654 Nomascus leucogenys 100.00 0.00e+00 991.00
IUUC-Opr-071198 Ochotona princeps 77.27 3.00e-147 515.00
IUUC-Ont-071547 Oreochromis niloticus 89.67 0.00e+00 954.00
IUUC-Oan-073045 Ornithorhynchus anatinus 92.82 0.00e+00 962.00
IUUC-Ocu-073812 Oryctolagus cuniculus 99.63 0.00e+00 1013.00
IUUC-Oba-075071 Oryza barthii 38.67 1.00e-100 360.00
IUUC-Obr-076614 Oryza brachyantha 38.81 1.00e-100 360.00
IUUC-Ogl-076963 Oryza glaberrima 38.67 2.00e-100 359.00
IUUC-Ogu-078436 Oryza glumaepatula 38.67 2.00e-100 359.00
IUUC-Oin-080021 Oryza indica 38.86 3.00e-100 359.00
IUUC-Olo-080298 Oryza longistaminata 38.67 4.00e-100 358.00
IUUC-Ome-081202 Oryza meridionalis 38.86 3.00e-100 358.00
IUUC-Oni-082604 Oryza nivara 38.86 2.00e-100 360.00
IUUC-Opu-083763 Oryza punctata 38.86 2.00e-100 360.00
IUUC-Oru-084243 Oryza rufipogon 38.86 2.00e-100 360.00
IUUC-Osa-086153 Oryza sativa 36.33 3.00e-81 296.00
IUUC-Ola-086670 Oryzias latipes 81.35 0.00e+00 954.00
IUUC-Oga-088723 Otolemur garnettii 90.81 0.00e+00 936.00
IUUC-Oar-090125 Ovis aries 99.68 0.00e+00 1045.00
IUUC-Ptr-090787 Pan troglodytes 100.00 0.00e+00 991.00
IUUC-Pan-092573 Papio anubis 99.27 3.00e-166 578.00
IUUC-Psi-093579 Pelodiscus sinensis 95.53 0.00e+00 942.00
IUUC-Pma-094254 Petromyzon marinus 83.59 0.00e+00 691.00
IUUC-Pno-094912 Phaeosphaeria nodorum 35.00 1.00e-78 288.00
IUUC-Ppa-095307 Physcomitrella patens 44.25 7.00e-106 377.00
IUUC-Pfo-096394 Poecilia formosa 89.86 0.00e+00 955.00
IUUC-Pab-098459 Pongo abelii 99.81 0.00e+00 1031.00
IUUC-Pop-099989 Populus trichocarpa 36.64 1.00e-86 313.00
IUUC-Pca-100574 Procavia capensis 99.12 5.00e-138 484.00
IUUC-Ppe-101881 Prunus persica 37.52 2.00e-84 306.00
IUUC-Pva-102404 Pteropus vampyrus 95.14 0.00e+00 924.00
IUUC-Pgr-103411 Puccinia graminis 31.38 1.00e-30 129.00
IUUC-Ptt-103705 Puccinia triticina 26.71 9.00e-46 179.00
IUUC-Pte-104023 Pyrenophora teres 36.15 6.00e-83 301.00
IUUC-Pyt-104759 Pyrenophora triticirepentis 35.54 8.00e-80 292.00
IUUC-Rno-105335 Rattus norvegicus 98.83 0.00e+00 981.00
IUUC-Sce-106152 Saccharomyces cerevisiae 33.61 3.00e-15 77.40
IUUC-Sha-106497 Sarcophilus harrisii 98.65 0.00e+00 989.00
IUUC-Sja-107894 Schizosaccharomyces japonicus 32.04 1.00e-67 250.00
IUUC-Spo-108235 Schizosaccharomyces pombe 32.83 9.00e-69 254.00
IUUC-Smo-109054 Selaginella moellendorffii 42.15 1.00e-110 393.00
IUUC-Sit-110575 Setaria italica 39.20 2.00e-101 363.00
IUUC-Sly-111167 Solanum lycopersicum 39.54 5.00e-95 342.00
IUUC-Stu-112726 Solanum tuberosum 36.40 4.00e-85 309.00
IUUC-Sar-113539 Sorex araneus 100.00 1.00e-122 433.00
IUUC-Sbi-114344 Sorghum bicolor 39.01 4.00e-100 358.00
IUUC-Sre-115051 Sporisorium reilianum 28.66 8.00e-64 238.00
IUUC-Ssc-115532 Sus scrofa 99.53 0.00e+00 1052.00
IUUC-Tgu-116728 Taeniopygia guttata 96.20 0.00e+00 1028.00
IUUC-Tru-118358 Takifugu rubripes 79.28 0.00e+00 918.00
IUUC-Tsy-119284 Tarsius syrichta 90.71 0.00e+00 876.00
IUUC-Tni-119720 Tetraodon nigroviridis 86.11 0.00e+00 906.00
IUUC-Tca-121103 Theobroma cacao 35.15 3.00e-84 306.00
IUUC-Tre-122234 Trichoderma reesei 36.48 2.00e-77 283.00
IUUC-Tvi-122376 Trichoderma virens 34.76 2.00e-44 173.00
IUUC-Tae-125635 Triticum aestivum 38.12 3.00e-95 342.00
IUUC-Tur-126726 Triticum urartu 36.22 9.00e-95 341.00
IUUC-Tme-126972 Tuber melanosporum 39.26 3.00e-98 353.00
IUUC-Tbe-128063 Tupaia belangeri 78.15 7.00e-172 597.00
IUUC-Ttr-129184 Tursiops truncatus 93.58 0.00e+00 911.00
IUUC-Uma-129354 Ustilago maydis 31.05 2.00e-49 190.00
IUUC-Vda-129770 Verticillium dahliae 34.60 3.00e-74 273.00
IUUC-Vpa-130400 Vicugna pacos 99.81 0.00e+00 984.00
IUUC-Vvi-130991 Vitis vinifera 36.85 1.00e-85 310.00
IUUC-Xtr-132619 Xenopus tropicalis 91.34 0.00e+00 972.00
IUUC-Xma-134128 Xiphophorus maculatus 89.86 0.00e+00 957.00
IUUC-Yli-134521 Yarrowia lipolytica 33.08 2.00e-60 226.00
IUUC-Zma-135772 Zea mays 38.81 9.00e-94 337.00
Created Date 25-Jun-2017

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