iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023332

Ensembl Protein ID

ENSCSAP00000008869.1

UniProt Accession

A0A0D9RJT0; A0A0D9RJT0_CHLSB

Genbank Protein ID

ENSCSAP00000008869

Protein Name

Protein kinase C

Genbank Nucleotide ID

AQIB01118964

Gene Name

PRKCI

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000012687.1	ENSCSAT00000010781.1	ENSCSAP00000008869.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	99.79	0.00e+00	976.00	IUUC-Hsa-046991

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MPCPGEDKSI YRRGARRWRK LYCANGHTFQ AKRFNRRAHC AICTDRIWGL GRQGYKCINC 60
KLLVHKKCHK LVTIECGRHS LPPEPVMPMD QSSMHSDHAQ TVIPYNPSSH ESLDQVGEEK 120

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Nucleotide Sequence
(Fasta)

GTGTAATTTG TATGTTTTAA ATATGCTGTT AACTCACGTT CATTTATTTT CTTTCAGTGT 60
TCCCTTGTGT ACCAGAACGT CCTGGGATGC CTTGTCCAGG AGAAGATAGT GAGTGTTTAT 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR034661--aPKC_iota
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR002219--PE/DAG-bd
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005634--C:nucleus
GO:0043220--C:Schmidt-Lanterman incisure
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0005543--F:phospholipid binding
GO:0004697--F:protein kinase C activity
GO:0007015--P:actin filament organization
GO:0045216--P:cell-cell junction organization
GO:0032869--P:cellular response to insulin stimulus
GO:0035089--P:establishment of apical/basal cell polarity
GO:0042462--P:eye photoreceptor cell development
GO:0035556--P:intracellular signal transduction
GO:0034351--P:negative regulation of glial cell apoptotic process
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0018105--P:peptidyl-serine phosphorylation
GO:2000353--P:positive regulation of endothelial cell apoptotic process
GO:0090004--P:positive regulation of establishment of protein localization to plasma membrane
GO:0060252--P:positive regulation of glial cell proliferation
GO:0046326--P:positive regulation of glucose import
GO:0010976--P:positive regulation of neuron projection development
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	99.17	0.00e+00	968.00
IUUC-Apl-003711	Anas platyrhynchos	95.66	0.00e+00	934.00
IUUC-Aca-005142	Anolis carolinensis	95.02	0.00e+00	926.00
IUUC-Ame-010977	Astyanax mexicanus	89.42	0.00e+00	855.00
IUUC-Bta-013414	Bos taurus	99.79	0.00e+00	976.00
IUUC-Bol-015169	Brassica oleracea	35.29	5.00e-51	196.00
IUUC-Cel-018340	Caenorhabditis elegans	62.45	0.00e+00	636.00
IUUC-Cja-019802	Callithrix jacchus	99.59	0.00e+00	972.00
IUUC-Cfa-021236	Canis familiaris	98.96	0.00e+00	932.00
IUUC-Cpo-022127	Cavia porcellus	97.93	0.00e+00	921.00
IUUC-Cho-025054	Choloepus hoffmanni	61.29	4.00e-72	265.00
IUUC-Cin-025740	Ciona intestinalis	63.06	2.00e-174	605.00
IUUC-Csv-026145	Ciona savignyi	64.79	4.00e-176	610.00
IUUC-Dre-028444	Danio rerio	89.42	0.00e+00	865.00
IUUC-Dno-029228	Dasypus novemcinctus	100.00	0.00e+00	648.00
IUUC-Dme-031630	Drosophila melanogaster	70.73	0.00e+00	686.00
IUUC-Ete-032633	Echinops telfairi	73.24	0.00e+00	631.00
IUUC-Eca-033572	Equus caballus	99.79	0.00e+00	977.00
IUUC-Eeu-035110	Erinaceus europaeus	98.76	0.00e+00	967.00
IUUC-Fca-035559	Felis catus	99.59	0.00e+00	976.00
IUUC-Fal-036953	Ficedula albicollis	96.47	0.00e+00	945.00
IUUC-Gmo-039334	Gadus morhua	89.83	0.00e+00	867.00
IUUC-Gga-040223	Gallus gallus	95.64	0.00e+00	939.00
IUUC-Gac-042113	Gasterosteus aculeatus	90.25	0.00e+00	874.00
IUUC-Ggo-044520	Gorilla gorilla	91.53	0.00e+00	860.00
IUUC-Hsa-046991	Homo sapiens	99.79	0.00e+00	976.00
IUUC-Lch-050263	Latimeria chalumnae	90.46	0.00e+00	882.00
IUUC-Loc-052221	Lepisosteus oculatus	91.29	0.00e+00	887.00
IUUC-Laf-053591	Loxodonta africana	99.38	0.00e+00	976.00
IUUC-Mcc-055118	Macaca mulatta	96.06	0.00e+00	930.00
IUUC-Mga-059886	Meleagris gallopavo	95.45	0.00e+00	932.00
IUUC-Mmr-060926	Microcebus murinus	99.79	0.00e+00	978.00
IUUC-Mdo-062698	Monodelphis domestica	97.47	0.00e+00	945.00
IUUC-Mmu-063689	Mus musculus	98.96	0.00e+00	966.00
IUUC-Mpu-066630	Mustela putorius furo	99.59	0.00e+00	975.00
IUUC-Mlu-067416	Myotis lucifugus	99.17	0.00e+00	927.00
IUUC-Nle-069811	Nomascus leucogenys	99.59	0.00e+00	974.00
IUUC-Opr-070466	Ochotona princeps	86.77	0.00e+00	753.00
IUUC-Ont-072278	Oreochromis niloticus	87.22	0.00e+00	863.00
IUUC-Oan-073651	Ornithorhynchus anatinus	98.62	0.00e+00	745.00
IUUC-Ocu-074383	Oryctolagus cuniculus	99.38	0.00e+00	974.00
IUUC-Ola-087283	Oryzias latipes	83.61	0.00e+00	658.00
IUUC-Oga-088337	Otolemur garnettii	89.30	0.00e+00	855.00
IUUC-Oar-089954	Ovis aries	99.79	0.00e+00	979.00
IUUC-Ptr-091673	Pan troglodytes	99.79	0.00e+00	976.00
IUUC-Pan-092494	Papio anubis	100.00	0.00e+00	978.00
IUUC-Psi-094044	Pelodiscus sinensis	96.47	0.00e+00	941.00
IUUC-Pfo-096661	Poecilia formosa	88.11	0.00e+00	854.00
IUUC-Pab-097659	Pongo abelii	99.79	0.00e+00	978.00
IUUC-Pca-101107	Procavia capensis	98.50	0.00e+00	809.00
IUUC-Rno-105790	Rattus norvegicus	99.38	0.00e+00	973.00
IUUC-Sha-106895	Sarcophilus harrisii	97.72	0.00e+00	934.00
IUUC-Sar-113513	Sorex araneus	99.59	5.00e-135	474.00
IUUC-Ssc-115835	Sus scrofa	99.17	0.00e+00	969.00
IUUC-Tgu-116874	Taeniopygia guttata	96.27	0.00e+00	945.00
IUUC-Tru-117823	Takifugu rubripes	88.37	0.00e+00	871.00
IUUC-Tsy-119154	Tarsius syrichta	99.38	0.00e+00	974.00
IUUC-Tni-119968	Tetraodon nigroviridis	86.26	0.00e+00	845.00
IUUC-Tbe-127238	Tupaia belangeri	83.37	0.00e+00	667.00
IUUC-Ttr-129208	Tursiops truncatus	99.79	0.00e+00	977.00
IUUC-Vpa-130363	Vicugna pacos	86.57	0.00e+00	806.00
IUUC-Xtr-132652	Xenopus tropicalis	88.61	0.00e+00	868.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence