iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116874

Ensembl Protein ID

ENSTGUP00000011303.1

UniProt Accession

H0ZL30; H0ZL30_TAEGU

Genbank Protein ID

ENSTGUP00000011303

Protein Name

Protein kinase C

Genbank Nucleotide ID

ABQF01023144

Gene Name

PRKCI

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000010959.1	ENSTGUT00000011425.1	ENSTGUP00000011303.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	7.90e-21	73.9	30	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
           +vrvk++ykg+i  + + +e++++fe L+++vr++++++n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l ++++
   Q: 30   QVRVKAYYKGDI--MITYFEPSISFEGLCSEVRDMCSFDNeQLFTMKWIDEEGDPCTVSSQLELEEAFRLYElNKDSELLIHVF 111
           69**********..88******************************************************************98 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MPTQRDGGAG STMSAPGGLG SSLGGDGAHQ VRVKAYYKGD IMITYFEPSI SFEGLCSEVR 60
DMCSFDNEQL FTMKWIDEEG DPCTVSSQLE LEEAFRLYEL NKDSELLIHV FPCVPERPGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGACGC AGCGGGACGG CGGCGCCGGG AGCACCATGT CGGCTCCGGG CGGCCTCGGG 60
AGCAGCCTCG GCGGGGACGG CGCCCACCAG GTCCGGGTGA AAGCCTACTA CAAGGGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR034661--aPKC_iota
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005634--C:nucleus
GO:0043220--C:Schmidt-Lanterman incisure
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0005543--F:phospholipid binding
GO:0004697--F:protein kinase C activity
GO:0007015--P:actin filament organization
GO:0045216--P:cell-cell junction organization
GO:0032869--P:cellular response to insulin stimulus
GO:0035089--P:establishment of apical/basal cell polarity
GO:0042462--P:eye photoreceptor cell development
GO:0035556--P:intracellular signal transduction
GO:0034351--P:negative regulation of glial cell apoptotic process
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0018105--P:peptidyl-serine phosphorylation
GO:2000353--P:positive regulation of endothelial cell apoptotic process
GO:0090004--P:positive regulation of establishment of protein localization to plasma membrane
GO:0060252--P:positive regulation of glial cell proliferation
GO:0046326--P:positive regulation of glucose import
GO:0010976--P:positive regulation of neuron projection development
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	95.99	0.00e+00	996.00
IUUC-Apl-003711	Anas platyrhynchos	98.40	0.00e+00	1096.00
IUUC-Aca-005142	Anolis carolinensis	96.69	0.00e+00	1100.00
IUUC-Ame-010977	Astyanax mexicanus	87.02	0.00e+00	983.00
IUUC-Bta-013414	Bos taurus	93.84	0.00e+00	1117.00
IUUC-Bol-015169	Brassica oleracea	35.29	7.00e-51	195.00
IUUC-Cel-018340	Caenorhabditis elegans	59.63	0.00e+00	705.00
IUUC-Cja-019802	Callithrix jacchus	96.27	0.00e+00	1082.00
IUUC-Cfa-021236	Canis familiaris	93.34	0.00e+00	1082.00
IUUC-Cpo-022127	Cavia porcellus	94.18	0.00e+00	1038.00
IUUC-Csa-023332	Chlorocebus sabaeus	96.27	0.00e+00	925.00
IUUC-Cho-025054	Choloepus hoffmanni	62.56	1.00e-117	416.00
IUUC-Cin-025740	Ciona intestinalis	59.56	0.00e+00	685.00
IUUC-Csv-026145	Ciona savignyi	79.49	2.00e-171	594.00
IUUC-Dre-028444	Danio rerio	87.85	0.00e+00	1005.00
IUUC-Dno-029228	Dasypus novemcinctus	99.03	0.00e+00	644.00
IUUC-Dme-031630	Drosophila melanogaster	66.45	0.00e+00	785.00
IUUC-Ete-032633	Echinops telfairi	70.88	2.00e-176	611.00
IUUC-Eca-033572	Equus caballus	96.62	0.00e+00	1088.00
IUUC-Eeu-035110	Erinaceus europaeus	95.99	0.00e+00	1105.00
IUUC-Fca-035559	Felis catus	93.84	0.00e+00	1117.00
IUUC-Fal-036953	Ficedula albicollis	99.64	0.00e+00	1112.00
IUUC-Gmo-039334	Gadus morhua	87.19	0.00e+00	1018.00
IUUC-Gga-040223	Gallus gallus	97.34	0.00e+00	1145.00
IUUC-Gac-042113	Gasterosteus aculeatus	88.02	0.00e+00	1027.00
IUUC-Ggo-044520	Gorilla gorilla	89.24	0.00e+00	1003.00
IUUC-Hsa-046991	Homo sapiens	93.68	0.00e+00	1113.00
IUUC-Lch-050263	Latimeria chalumnae	88.19	0.00e+00	1041.00
IUUC-Loc-052221	Lepisosteus oculatus	89.18	0.00e+00	1020.00
IUUC-Laf-053591	Loxodonta africana	94.18	0.00e+00	1118.00
IUUC-Mcc-055118	Macaca mulatta	92.01	0.00e+00	1080.00
IUUC-Mga-059886	Meleagris gallopavo	98.40	0.00e+00	1098.00
IUUC-Mmr-060926	Microcebus murinus	94.01	0.00e+00	1117.00
IUUC-Mdo-062698	Monodelphis domestica	93.54	0.00e+00	1094.00
IUUC-Mmu-063689	Mus musculus	93.84	0.00e+00	1105.00
IUUC-Mpu-066630	Mustela putorius furo	96.17	0.00e+00	1109.00
IUUC-Mlu-067416	Myotis lucifugus	90.86	0.00e+00	1038.00
IUUC-Nle-069811	Nomascus leucogenys	93.34	0.00e+00	1111.00
IUUC-Opr-070466	Ochotona princeps	84.30	0.00e+00	719.00
IUUC-Ont-072278	Oreochromis niloticus	86.68	0.00e+00	961.00
IUUC-Oan-073651	Ornithorhynchus anatinus	99.17	0.00e+00	746.00
IUUC-Ocu-074383	Oryctolagus cuniculus	93.84	0.00e+00	1114.00
IUUC-Ola-087283	Oryzias latipes	80.63	0.00e+00	795.00
IUUC-Oga-088337	Otolemur garnettii	86.61	0.00e+00	1004.00
IUUC-Oar-089954	Ovis aries	94.95	0.00e+00	1092.00
IUUC-Ptr-091673	Pan troglodytes	93.68	0.00e+00	1113.00
IUUC-Pan-092494	Papio anubis	93.84	0.00e+00	1115.00
IUUC-Psi-094044	Pelodiscus sinensis	94.07	0.00e+00	1107.00
IUUC-Pfo-096661	Poecilia formosa	85.53	0.00e+00	980.00
IUUC-Pab-097659	Pongo abelii	93.51	0.00e+00	1112.00
IUUC-Pca-101107	Procavia capensis	95.74	0.00e+00	767.00
IUUC-Rno-105790	Rattus norvegicus	93.84	0.00e+00	1110.00
IUUC-Sha-106895	Sarcophilus harrisii	96.82	0.00e+00	1068.00
IUUC-Sar-113513	Sorex araneus	94.39	2.00e-175	608.00
IUUC-Ssc-115835	Sus scrofa	95.98	0.00e+00	998.00
IUUC-Tru-117823	Takifugu rubripes	88.34	0.00e+00	988.00
IUUC-Tsy-119154	Tarsius syrichta	96.44	0.00e+00	1087.00
IUUC-Tni-119968	Tetraodon nigroviridis	85.27	0.00e+00	972.00
IUUC-Tbe-127238	Tupaia belangeri	76.36	0.00e+00	728.00
IUUC-Ttr-129208	Tursiops truncatus	93.84	0.00e+00	1115.00
IUUC-Vpa-130363	Vicugna pacos	84.08	0.00e+00	951.00
IUUC-Xtr-132652	Xenopus tropicalis	85.88	0.00e+00	1022.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence