iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132449

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AAMC01048033

Gene Name

bap1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000000091.3	ENSXETT00000000167.3	ENSXETP00000000167.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.30e-152	507.6	1	673

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 16   glftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAl 104
           glftllvedfgvk++ qvee+y+L++++    ++pv+g+++lFk++e+r+s+rk++++ +d++v+++++++++ffa+q+i+NsCat+Al
   Q: 1    GLFTLLVEDFGVKGV-QVEEIYDLQSKC----PGPVYGFIFLFKWIEERRSRRKVSTLLDDTSVMEDEVVNNMFFAHQLIPNSCATHAL 84
           79*************.************....********************************************************* PP
   S: 105  lsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyel 193
           lsvllnc+ +  +lG+tlsr+ke+tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q++ ++++t+eafhfvsyv+i+grl+el
   Q: 85   LSVLLNCSGV--HLGPTLSRIKEFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLFEL 171
           ********99..9**************************************************************************** PP
   S: 194  dglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid................... 259
           dglk++P+d+g++ e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk++                   
   Q: 172  DGLKVYPIDHGPWAEDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRLKYESKLHILKMNrqtvlealqqlirvtqpel 258
           ***************************..************************************************************ PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 259  iqaqkptegqsteetksaalkapvsqeshrahhgshrsatdvgaeppgalirgpvmsayskpnslaqnggtvaapasrlpafldnhnya 347
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 348  kspmqeeedlaagvgrsrgvpppapdtdeeeeeetenvrrpltppgfkrrsseplppppgpepgvlaeklketqrdlcsplsiktgapt 436
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 437  aphsqpsptpsnestdtaseigsafnsplrsplrsanptrpsspvtlhlskvlfgeeepllrldcvrynravrelgphistgilhlskd 525
           ***************************************************************************************** PP
   S: 260  ................................................keLlkLlkdieseeekieaqlddekekrkkfkiddirRten 300
                                                           keLl+Llk++e+e+   ea+l +e ekrkkfkidd+rRt+n
   Q: 526  gylcplsrletgkvspkgnkveepressepdtersrvtevpqgekfspKELLALLKCVEAEISSSEACLREELEKRKKFKIDDQRRTHN 614
           ***************************************************************************************** PP
   S: 301  ydeficifikdlaregilrklveetisevrefgvnegrlakqrkqgrekkirplkrkrk 359
           ydefic fi++la+eg+l+ lve++is++r++gv++grl+kqrk++r+k++rp+k+kr+
   Q: 615  YDEFICAFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ 673
           *********************************************************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

GLFTLLVEDF GVKGVQVEEI YDLQSKCPGP VYGFIFLFKW IEERRSRRKV STLLDDTSVM 60
EDEVVNNMFF AHQLIPNSCA THALLSVLLN CSGVHLGPTL SRIKEFTKGF SPESKGYAIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGACTTTT TACCCTGCTG GTTGAAGATT TTGGTACGTA CCAAGTAGGA GGAGCTTATA 60
TTATAGCTGG GGCTGAGAAC TTGAGAATAA TATATTTAAA TGCAAGGTTG TTACTGGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	70.58	0.00e+00	911.00
IUUC-Apl-003405	Anas platyrhynchos	58.76	9.00e-142	496.00
IUUC-Aca-004836	Anolis carolinensis	76.86	3.00e-169	588.00
IUUC-Ame-011946	Astyanax mexicanus	60.87	0.00e+00	803.00
IUUC-Bta-013131	Bos taurus	66.02	0.00e+00	761.00
IUUC-Cja-019599	Callithrix jacchus	71.41	0.00e+00	935.00
IUUC-Cfa-021003	Canis familiaris	71.13	0.00e+00	907.00
IUUC-Cpo-022143	Cavia porcellus	69.96	0.00e+00	922.00
IUUC-Csa-023477	Chlorocebus sabaeus	71.27	0.00e+00	929.00
IUUC-Cho-024734	Choloepus hoffmanni	68.33	6.00e-84	305.00
IUUC-Csv-025842	Ciona savignyi	59.92	2.00e-87	316.00
IUUC-Dre-027793	Danio rerio	61.98	0.00e+00	832.00
IUUC-Dno-029253	Dasypus novemcinctus	71.45	0.00e+00	935.00
IUUC-Dor-030891	Dipodomys ordii	65.09	0.00e+00	837.00
IUUC-Dme-031796	Drosophila melanogaster	59.46	2.00e-85	309.00
IUUC-Ete-032646	Echinops telfairi	90.72	2.00e-124	439.00
IUUC-Eca-033805	Equus caballus	71.43	0.00e+00	922.00
IUUC-Eeu-035216	Erinaceus europaeus	71.48	1.00e-108	386.00
IUUC-Fca-035611	Felis catus	70.15	0.00e+00	897.00
IUUC-Fal-037186	Ficedula albicollis	69.33	0.00e+00	834.00
IUUC-Gmo-038824	Gadus morhua	68.07	5.00e-165	574.00
IUUC-Gga-040875	Gallus gallus	71.09	0.00e+00	923.00
IUUC-Gac-042226	Gasterosteus aculeatus	64.56	0.00e+00	857.00
IUUC-Ggo-045122	Gorilla gorilla	71.17	0.00e+00	939.00
IUUC-Hsa-045882	Homo sapiens	71.03	0.00e+00	939.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	71.59	0.00e+00	918.00
IUUC-Lch-049960	Latimeria chalumnae	65.45	0.00e+00	847.00
IUUC-Loc-052408	Lepisosteus oculatus	67.18	2.00e-160	558.00
IUUC-Laf-054187	Loxodonta africana	70.99	0.00e+00	939.00
IUUC-Mcc-055273	Macaca mulatta	71.15	0.00e+00	913.00
IUUC-Meu-056267	Macropus eugenii	93.28	1.00e-137	483.00
IUUC-Mga-059958	Meleagris gallopavo	94.53	3.00e-149	520.00
IUUC-Mmr-061280	Microcebus murinus	70.83	0.00e+00	916.00
IUUC-Mdo-062625	Monodelphis domestica	72.49	0.00e+00	969.00
IUUC-Mmu-063853	Mus musculus	70.85	0.00e+00	913.00
IUUC-Mlu-067771	Myotis lucifugus	69.82	0.00e+00	910.00
IUUC-Opr-070741	Ochotona princeps	71.03	0.00e+00	932.00
IUUC-Ont-072172	Oreochromis niloticus	64.44	0.00e+00	873.00
IUUC-Oan-073167	Ornithorhynchus anatinus	71.18	0.00e+00	953.00
IUUC-Ocu-074176	Oryctolagus cuniculus	71.23	0.00e+00	905.00
IUUC-Ola-087203	Oryzias latipes	85.32	7.00e-128	449.00
IUUC-Oga-089153	Otolemur garnettii	71.61	0.00e+00	929.00
IUUC-Oar-090008	Ovis aries	71.94	0.00e+00	927.00
IUUC-Ptr-091234	Pan troglodytes	71.17	0.00e+00	940.00
IUUC-Pan-092005	Papio anubis	71.49	0.00e+00	935.00
IUUC-Psi-093995	Pelodiscus sinensis	78.84	4.00e-173	601.00
IUUC-Pma-094110	Petromyzon marinus	85.07	2.00e-66	246.00
IUUC-Pfo-097418	Poecilia formosa	65.16	0.00e+00	864.00
IUUC-Pab-098267	Pongo abelii	71.17	0.00e+00	915.00
IUUC-Pca-101084	Procavia capensis	70.13	0.00e+00	868.00
IUUC-Pva-102292	Pteropus vampyrus	70.38	2.00e-179	622.00
IUUC-Rno-105251	Rattus norvegicus	69.37	0.00e+00	895.00
IUUC-Sha-107100	Sarcophilus harrisii	72.77	0.00e+00	977.00
IUUC-Sar-113559	Sorex araneus	64.27	8.00e-118	417.00
IUUC-Ssc-115688	Sus scrofa	70.61	0.00e+00	917.00
IUUC-Tgu-117424	Taeniopygia guttata	70.65	0.00e+00	962.00
IUUC-Tru-118585	Takifugu rubripes	65.27	0.00e+00	858.00
IUUC-Tsy-119299	Tarsius syrichta	58.80	0.00e+00	654.00
IUUC-Tni-120808	Tetraodon nigroviridis	64.73	0.00e+00	855.00
IUUC-Tbe-127705	Tupaia belangeri	75.56	2.00e-141	494.00
IUUC-Ttr-128225	Tursiops truncatus	70.57	0.00e+00	909.00
IUUC-Vpa-130193	Vicugna pacos	73.66	7.00e-96	344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence