iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
PINA	Mentha
Post-translational Modifications (PTMs)
UniProt
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UIM	UIM	11406394; 23747397
ULD/UDP/UFD/UBX	UBX	23747397

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UIM	0.013	16.4	328	346
ULD/UDP/UFD/UBX	2.00e-14	54.8	387	464

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +E+eeLq+Ala Sl++ ++
   Q: 328  EEEEELQRALAASLEDNNM 346
           7**************9876 PP

ULD/UDP/UFD/UBX

   S: 3    teqatlqiRlpdGkrlvrkFpssttleqiyqfve..yllvessdpFeLvspfP..rrtlkpeehmstlqeagLvpsgsl 77
           + q+++ iRlp+G+rl+r+F +++t++ ++ f+    +++e+++p +L++++P   +tl+ e++  tl+++g+++s++ 
   Q: 387  SLQCRVGIRLPNGQRLQRNFLKTDTIQLLWSFCYsqLEESERKKPLKLTQAIPgeSKTLEYESNL-TLEQSGVANSMIS 464
           569*******************************988899999*********************6.*********9975 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Acts as a bridge between CDC48A and ubiquitin, suggesting a role in targeted protein degradation.

Protein Sequence
(Fasta)

MEGMLSSGDQ QRLVSSFLEI AVGQTAETAR QFLQATSWKL EEAIQLFYIG NEGGMLQSGT 60
HTQPASNDDA AAQSWGAATG TGNEMILPND VDEVRAPLPV VRETLYGESM YYGAMRVGNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTTTTGT GAACAAATCC GACCGAGAGA GAGAGAGAGA TATATTTTTG GCAGTAAGAT 60
CAAATTTTGG CATTGGTAAG TTGTTGTTCC TTCTTCTCCT CCCGCAGGAT TCGACTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR017346--UBX_7/2
IPR001012--UBX_dom
IPR003903--UIM_dom

PROSITE

PS50033--UBX
PS50330--UIM

Pfam

PF00789--UBX

SMART

SM00594--UAS

Gene Ontology

GO:0005634--C:nucleus
GO:0030674--F:protein binding, bridging

KEGG

ath:AT1G14570

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000182	Aegilops tauschii	51.98	4.00e-101	360.00
IUUC-Aml-001944	Ailuropoda melanoleuca	27.79	3.00e-34	138.00
IUUC-Atr-002562	Amborella trichopoda	52.00	4.00e-131	460.00
IUUC-Apl-003869	Anas platyrhynchos	28.95	1.00e-35	143.00
IUUC-Aca-004442	Anolis carolinensis	29.46	3.00e-36	145.00
IUUC-Aly-006399	Arabidopsis lyrata	95.13	0.00e+00	829.00
IUUC-Ago-007718	Ashbya gossypii	37.07	9.00e-22	97.40
IUUC-Acl-008032	Aspergillus clavatus	25.15	2.00e-24	106.00
IUUC-Afl-008654	Aspergillus flavus	24.35	1.00e-23	103.00
IUUC-Afu-008821	Aspergillus fumigatus	26.89	8.00e-23	100.00
IUUC-Ani-009458	Aspergillus nidulans	26.67	2.00e-22	99.80
IUUC-Ang-009569	Aspergillus niger	25.05	3.00e-25	108.00
IUUC-Aor-010044	Aspergillus oryzae	24.35	1.00e-23	103.00
IUUC-Ate-010483	Aspergillus terreus	24.95	7.00e-24	104.00
IUUC-Bgr-012199	Blumeria graminis	32.31	2.00e-26	112.00
IUUC-Bta-012363	Bos taurus	28.15	2.00e-35	142.00
IUUC-Bci-013929	Botrytis cinerea	28.09	2.00e-25	109.00
IUUC-Bdi-014936	Brachypodium distachyon	48.95	1.00e-114	405.00
IUUC-Bol-016354	Brassica oleracea	87.23	0.00e+00	703.00
IUUC-Bra-016632	Brassica rapa	87.23	0.00e+00	717.00
IUUC-Cja-019055	Callithrix jacchus	28.40	9.00e-36	144.00
IUUC-Cfa-020168	Canis familiaris	28.15	1.00e-35	143.00
IUUC-Cpo-021430	Cavia porcellus	28.15	6.00e-33	134.00
IUUC-Cre-022974	Chlamydomonas reinhardtii	31.09	5.00e-34	138.00
IUUC-Csa-023976	Chlorocebus sabaeus	28.10	3.00e-35	142.00
IUUC-Cho-025035	Choloepus hoffmanni	31.30	8.00e-34	137.00
IUUC-Cin-025322	Ciona intestinalis	37.64	8.00e-34	137.00
IUUC-Csv-025965	Ciona savignyi	30.61	2.00e-32	132.00
IUUC-Dre-027359	Danio rerio	29.45	9.00e-35	140.00
IUUC-Dno-029627	Dasypus novemcinctus	29.19	3.00e-34	139.00
IUUC-Dor-031133	Dipodomys ordii	22.14	3.00e-10	58.90
IUUC-Dse-031560	Dothistroma septosporum	25.93	3.00e-25	108.00
IUUC-Dme-031981	Drosophila melanogaster	38.17	3.00e-23	102.00
IUUC-Ete-033025	Echinops telfairi	27.27	7.00e-33	134.00
IUUC-Eca-034228	Equus caballus	28.15	1.00e-35	143.00
IUUC-Eeu-034469	Erinaceus europaeus	33.54	3.00e-25	108.00
IUUC-Fca-036404	Felis catus	28.10	3.00e-35	142.00
IUUC-Fal-036686	Ficedula albicollis	29.63	9.00e-35	140.00
IUUC-Fox-037758	Fusarium oxysporum	34.62	3.00e-23	102.00
IUUC-Fso-038081	Fusarium solani	34.07	1.00e-22	100.00
IUUC-Gmo-038652	Gadus morhua	29.29	1.00e-32	133.00
IUUC-Ggr-039845	Gaeumannomyces graminis	26.79	2.00e-24	106.00
IUUC-Gga-040734	Gallus gallus	33.96	2.00e-23	102.00
IUUC-Gac-041490	Gasterosteus aculeatus	27.51	2.00e-33	136.00
IUUC-Gma-042709	Glycine max	58.38	2.00e-145	508.00
IUUC-Ggo-044872	Gorilla gorilla	24.85	6.00e-22	98.20
IUUC-Hsa-046827	Homo sapiens	28.15	1.00e-35	143.00
IUUC-Hvu-047400	Hordeum vulgare	51.32	3.00e-100	357.00
IUUC-Itr-048785	Ictidomys tridecemlineatus	30.60	8.00e-34	137.00
IUUC-Kpa-049161	Komagataella pastoris	27.43	2.00e-33	135.00
IUUC-Lch-049556	Latimeria chalumnae	30.41	8.00e-36	144.00
IUUC-Lpe-051673	Leersia perrieri	50.00	1.00e-115	409.00
IUUC-Loc-051741	Lepisosteus oculatus	28.36	3.00e-33	135.00
IUUC-Lma-053009	Leptosphaeria maculans	24.27	5.00e-27	115.00
IUUC-Laf-054106	Loxodonta africana	27.79	4.00e-34	138.00
IUUC-Mcc-054866	Macaca mulatta	28.15	1.00e-35	143.00
IUUC-Meu-056868	Macropus eugenii	35.87	4.00e-32	131.00
IUUC-Mor-057056	Magnaporthe oryzae	32.04	1.00e-20	94.00
IUUC-Mpo-057332	Magnaporthe poae	28.61	2.00e-22	100.00
IUUC-Mtr-058153	Medicago truncatula	58.66	2.00e-148	518.00
IUUC-Mga-059940	Meleagris gallopavo	29.13	1.00e-35	143.00
IUUC-Mmr-060737	Microcebus murinus	28.15	1.00e-35	143.00
IUUC-Mdo-062970	Monodelphis domestica	28.74	2.00e-36	146.00
IUUC-Mmu-063481	Mus musculus	28.15	1.00e-35	143.00
IUUC-Mac-065522	Musa acuminata	52.44	1.00e-129	455.00
IUUC-Mpu-065853	Mustela putorius furo	28.10	3.00e-35	142.00
IUUC-Mlu-068056	Myotis lucifugus	29.31	5.00e-36	144.00
IUUC-Nfi-068479	Neosartorya fischeri	33.33	6.00e-21	94.70
IUUC-Ncr-068638	Neurospora crassa	32.97	2.00e-20	93.60
IUUC-Nle-070140	Nomascus leucogenys	35.87	2.00e-32	132.00
IUUC-Opr-071163	Ochotona princeps	35.33	2.00e-31	129.00
IUUC-Ont-071318	Oreochromis niloticus	27.99	1.00e-33	137.00
IUUC-Oan-073323	Ornithorhynchus anatinus	49.37	6.00e-20	88.60
IUUC-Ocu-074018	Oryctolagus cuniculus	28.15	2.00e-35	143.00
IUUC-Oba-074980	Oryza barthii	50.00	6.00e-123	433.00
IUUC-Obr-076741	Oryza brachyantha	53.68	6.00e-104	370.00
IUUC-Ogl-077363	Oryza glaberrima	50.00	4.00e-123	434.00
IUUC-Ogu-078011	Oryza glumaepatula	50.20	1.00e-120	426.00
IUUC-Oin-079454	Oryza indica	50.20	9.00e-121	426.00
IUUC-Olo-080898	Oryza longistaminata	47.83	2.00e-102	365.00
IUUC-Ome-081479	Oryza meridionalis	49.90	5.00e-119	420.00
IUUC-Oni-082128	Oryza nivara	46.83	3.00e-116	411.00
IUUC-Opu-083193	Oryza punctata	47.90	2.00e-103	368.00
IUUC-Oru-084233	Oryza rufipogon	50.20	2.00e-120	425.00
IUUC-Osa-085483	Oryza sativa	50.20	9.00e-121	426.00
IUUC-Ola-087217	Oryzias latipes	36.02	1.00e-32	134.00
IUUC-Oga-088688	Otolemur garnettii	28.15	1.00e-35	143.00
IUUC-Oar-090133	Ovis aries	28.15	1.00e-35	143.00
IUUC-Pan-092026	Papio anubis	24.74	7.00e-29	121.00
IUUC-Psi-093468	Pelodiscus sinensis	29.19	2.00e-34	139.00
IUUC-Pma-094180	Petromyzon marinus	32.60	1.00e-30	127.00
IUUC-Pno-095137	Phaeosphaeria nodorum	26.32	1.00e-30	127.00
IUUC-Ppa-095977	Physcomitrella patens	41.46	1.00e-94	339.00
IUUC-Pfo-097017	Poecilia formosa	30.00	7.00e-34	137.00
IUUC-Pab-098140	Pongo abelii	28.15	1.00e-35	143.00
IUUC-Pop-098981	Populus trichocarpa	61.26	7.00e-156	542.00
IUUC-Pca-100856	Procavia capensis	30.53	3.00e-33	135.00
IUUC-Ppe-101162	Prunus persica	60.18	3.00e-110	390.00
IUUC-Pva-103250	Pteropus vampyrus	31.25	2.00e-31	129.00
IUUC-Pte-104178	Pyrenophora teres	25.43	2.00e-28	119.00
IUUC-Pyt-104744	Pyrenophora triticirepentis	25.82	5.00e-29	121.00
IUUC-Rno-105201	Rattus norvegicus	28.15	1.00e-35	143.00
IUUC-Sce-106451	Saccharomyces cerevisiae	26.42	6.00e-18	85.10
IUUC-Sha-107343	Sarcophilus harrisii	28.31	3.00e-34	138.00
IUUC-Sja-107754	Schizosaccharomyces japonicus	31.31	3.00e-34	139.00
IUUC-Spo-108295	Schizosaccharomyces pombe	28.51	1.00e-37	150.00
IUUC-Sit-109720	Setaria italica	49.69	2.00e-118	418.00
IUUC-Sly-111080	Solanum lycopersicum	56.15	2.00e-148	518.00
IUUC-Stu-112704	Solanum tuberosum	56.31	2.00e-147	514.00
IUUC-Sbi-114212	Sorghum bicolor	48.25	3.00e-117	414.00
IUUC-Ssc-116258	Sus scrofa	28.28	3.00e-36	145.00
IUUC-Tgu-116707	Taeniopygia guttata	28.74	4.00e-35	141.00
IUUC-Tru-118460	Takifugu rubripes	28.57	1.00e-34	140.00
IUUC-Tsy-119242	Tarsius syrichta	30.92	2.00e-33	135.00
IUUC-Tni-120184	Tetraodon nigroviridis	27.70	7.00e-34	137.00
IUUC-Tca-121697	Theobroma cacao	62.79	1.00e-164	572.00
IUUC-Tre-122170	Trichoderma reesei	26.73	8.00e-23	101.00
IUUC-Tvi-122652	Trichoderma virens	33.15	2.00e-22	99.80
IUUC-Tae-125283	Triticum aestivum	49.08	8.00e-116	409.00
IUUC-Tur-126601	Triticum urartu	50.24	1.00e-104	372.00
IUUC-Tme-126975	Tuber melanosporum	24.15	5.00e-26	111.00
IUUC-Tbe-128096	Tupaia belangeri	41.43	3.00e-31	129.00
IUUC-Ttr-128699	Tursiops truncatus	26.69	7.00e-31	127.00
IUUC-Vda-129909	Verticillium dahliae	37.97	2.00e-13	69.30
IUUC-Vpa-130207	Vicugna pacos	28.15	2.00e-35	142.00
IUUC-Vvi-130875	Vitis vinifera	58.86	1.00e-150	525.00
IUUC-Xtr-132737	Xenopus tropicalis	28.61	1.00e-36	146.00
IUUC-Xma-133046	Xiphophorus maculatus	29.66	4.00e-34	138.00
IUUC-Yli-134393	Yarrowia lipolytica	25.55	1.00e-24	107.00
IUUC-Zma-135572	Zea mays	50.00	5.00e-120	423.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence