iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093725

Ensembl Protein ID

ENSPSIP00000002322.1

UniProt Accession

K7F2R2; K7F2R2_PELSI

Genbank Protein ID

ENSPSIP00000002322

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01150946

Gene Name

VCP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000002302.1	ENSPSIT00000002329.1	ENSPSIP00000002322.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	96.59	0.00e+00	1392.00	IUUC-Hsa-046162
UBD/Other/Other	69.61	0.00e+00	1052.00	IUUC-Sce-106244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LFLSSSKADD LSTAILKQKN RPNRLIVDEA INEDNSVVSL SQAKMDELQL FRGDTVLLKG 60
KKRREAVCIV LSDDTCSDEK IRMNRVVRNN LRVRLGDVIS IQPCPDVKYG KRIHVLPIDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTTCTTT CCAGTTCTAA AGCGGATGAT TTATCCACTG CAATCCTAAA GCAGAAGAAC 60
AGGCCCAATC GGTTAATTGT TGACGAAGCC ATCAATGAGG ACAACAGTGT TGTGTCACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR005938--AAA_ATPase_CDC48
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
IPR015415--Vps4_C

PROSITE

PS00674--AAA

Pfam

PF00004--AAA
PF02933--CDC48_2
PF02359--CDC48_N
PF09336--Vps4_C

SMART

SM00382--AAA
SM01072--CDC48_2
SM01073--CDC48_N

Gene Ontology

GO:0005829--C:cytosol
GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0070062--C:extracellular exosome
GO:0005811--C:lipid particle
GO:0043209--C:myelin sheath
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000502--C:proteasome complex
GO:0035861--C:site of double-strand break
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1990730--C:VCP-NSFL1C complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0035800--F:deubiquitinase activator activity
GO:0003723--F:RNA binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070842--P:aggresome assembly
GO:0046034--P:ATP metabolic process
GO:0097352--P:autophagosome maturation
GO:0006302--P:double-strand break repair
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0072389--P:flavin adenine dinucleotide catabolic process
GO:0006734--P:NADH metabolic process
GO:2001171--P:positive regulation of ATP biosynthetic process
GO:1903007--P:positive regulation of Lys63-specific deubiquitinase activity
GO:0010918--P:positive regulation of mitochondrial membrane potential
GO:1903862--P:positive regulation of oxidative phosphorylation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0034214--P:protein hexamerization
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0016567--P:protein ubiquitination
GO:1903715--P:regulation of aerobic respiration
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0019985--P:translesion synthesis
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0019079--P:viral genome replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000524	Aegilops tauschii	78.78	0.00e+00	1151.00
IUUC-Aml-001849	Ailuropoda melanoleuca	96.73	0.00e+00	1397.00
IUUC-Atr-002619	Amborella trichopoda	78.34	0.00e+00	1199.00
IUUC-Apl-004070	Anas platyrhynchos	96.99	0.00e+00	1393.00
IUUC-Aca-004847	Anolis carolinensis	96.85	0.00e+00	1394.00
IUUC-Aly-005406	Arabidopsis lyrata	77.59	0.00e+00	1174.00
IUUC-Ath-006796	Arabidopsis thaliana	77.98	0.00e+00	1182.00
IUUC-Ago-008001	Ashbya gossypii	70.44	0.00e+00	1003.00
IUUC-Acl-008066	Aspergillus clavatus	72.07	0.00e+00	1068.00
IUUC-Afl-008505	Aspergillus flavus	71.99	0.00e+00	1077.00
IUUC-Afu-008840	Aspergillus fumigatus	72.46	0.00e+00	1092.00
IUUC-Ani-009368	Aspergillus nidulans	71.78	0.00e+00	1082.00
IUUC-Ang-009724	Aspergillus niger	72.35	0.00e+00	1080.00
IUUC-Aor-010204	Aspergillus oryzae	71.99	0.00e+00	1077.00
IUUC-Ate-010370	Aspergillus terreus	72.51	0.00e+00	1083.00
IUUC-Ame-011388	Astyanax mexicanus	95.78	0.00e+00	1372.00
IUUC-Bgr-012223	Blumeria graminis	71.45	0.00e+00	1098.00
IUUC-Bta-013188	Bos taurus	96.46	0.00e+00	1394.00
IUUC-Bci-013831	Botrytis cinerea	71.84	0.00e+00	1083.00
IUUC-Bdi-014967	Brachypodium distachyon	78.81	0.00e+00	1195.00
IUUC-Bol-016113	Brassica oleracea	78.01	0.00e+00	1183.00
IUUC-Bra-017796	Brassica rapa	78.01	0.00e+00	1184.00
IUUC-Cel-018243	Caenorhabditis elegans	78.17	0.00e+00	1157.00
IUUC-Cja-019904	Callithrix jacchus	95.81	0.00e+00	1344.00
IUUC-Cfa-020304	Canis familiaris	96.46	0.00e+00	1393.00
IUUC-Cpo-021518	Cavia porcellus	96.85	0.00e+00	1392.00
IUUC-Cre-022719	Chlamydomonas reinhardtii	78.38	0.00e+00	1186.00
IUUC-Csa-023444	Chlorocebus sabaeus	96.59	0.00e+00	1392.00
IUUC-Cho-024482	Choloepus hoffmanni	95.92	0.00e+00	1379.00
IUUC-Cin-025517	Ciona intestinalis	84.38	0.00e+00	1226.00
IUUC-Csv-026060	Ciona savignyi	84.86	0.00e+00	1274.00
IUUC-Cgl-026690	Colletotrichum gloeosporioides	72.27	0.00e+00	1108.00
IUUC-Cne-026910	Cryptococcus neoformans	72.94	0.00e+00	1116.00
IUUC-Cme-027145	Cyanidioschyzon merolae	74.03	0.00e+00	1109.00
IUUC-Dre-028487	Danio rerio	96.04	0.00e+00	1372.00
IUUC-Dno-029257	Dasypus novemcinctus	96.59	0.00e+00	1392.00
IUUC-Dor-030473	Dipodomys ordii	94.90	0.00e+00	1342.00
IUUC-Dse-031319	Dothistroma septosporum	70.30	0.00e+00	1061.00
IUUC-Dme-032203	Drosophila melanogaster	82.70	0.00e+00	1214.00
IUUC-Eca-033311	Equus caballus	96.47	0.00e+00	1387.00
IUUC-Eeu-035293	Erinaceus europaeus	97.72	0.00e+00	751.00
IUUC-Fca-036097	Felis catus	96.81	0.00e+00	1322.00
IUUC-Fal-037292	Ficedula albicollis	97.12	0.00e+00	1400.00
IUUC-Fox-037827	Fusarium oxysporum	72.16	0.00e+00	1116.00
IUUC-Fso-038226	Fusarium solani	72.60	0.00e+00	1118.00
IUUC-Gmo-039157	Gadus morhua	88.68	0.00e+00	1256.00
IUUC-Ggr-039951	Gaeumannomyces graminis	72.03	0.00e+00	1080.00
IUUC-Gga-041183	Gallus gallus	97.12	0.00e+00	1399.00
IUUC-Gac-042039	Gasterosteus aculeatus	95.14	0.00e+00	1343.00
IUUC-Gma-044090	Glycine max	77.66	0.00e+00	1196.00
IUUC-Ggo-045568	Gorilla gorilla	96.59	0.00e+00	1392.00
IUUC-Hsa-046162	Homo sapiens	96.59	0.00e+00	1392.00
IUUC-Hvu-047107	Hordeum vulgare	80.62	0.00e+00	993.00
IUUC-Itr-047885	Ictidomys tridecemlineatus	96.34	0.00e+00	1390.00
IUUC-Kpa-049220	Komagataella pastoris	69.62	0.00e+00	1058.00
IUUC-Lch-050657	Latimeria chalumnae	88.38	0.00e+00	1210.00
IUUC-Lpe-051083	Leersia perrieri	79.00	0.00e+00	1184.00
IUUC-Loc-052064	Lepisosteus oculatus	96.31	0.00e+00	1374.00
IUUC-Lma-053323	Leptosphaeria maculans	72.40	0.00e+00	1092.00
IUUC-Laf-054574	Loxodonta africana	96.85	0.00e+00	1395.00
IUUC-Mcc-055448	Macaca mulatta	96.59	0.00e+00	1392.00
IUUC-Meu-056316	Macropus eugenii	89.88	0.00e+00	1264.00
IUUC-Mor-057057	Magnaporthe oryzae	72.03	0.00e+00	1083.00
IUUC-Mpo-057406	Magnaporthe poae	72.43	0.00e+00	1077.00
IUUC-Mtr-057648	Medicago truncatula	77.88	0.00e+00	1204.00
IUUC-Mla-059156	Melampsora laricipopulina	75.39	0.00e+00	1163.00
IUUC-Mga-060004	Meleagris gallopavo	90.32	0.00e+00	1159.00
IUUC-Mvi-060488	Microbotryum violaceum	73.97	0.00e+00	1140.00
IUUC-Mmr-061027	Microcebus murinus	96.85	0.00e+00	1392.00
IUUC-Mdo-062159	Monodelphis domestica	96.85	0.00e+00	1396.00
IUUC-Mmu-063633	Mus musculus	96.59	0.00e+00	1392.00
IUUC-Mac-064919	Musa acuminata	78.12	0.00e+00	1196.00
IUUC-Mpu-066078	Mustela putorius furo	96.46	0.00e+00	1394.00
IUUC-Mlu-067757	Myotis lucifugus	96.46	0.00e+00	1392.00
IUUC-Nfi-068533	Neosartorya fischeri	72.33	0.00e+00	1082.00
IUUC-Ncr-068775	Neurospora crassa	72.73	0.00e+00	1052.00
IUUC-Nle-069424	Nomascus leucogenys	96.85	0.00e+00	1395.00
IUUC-Opr-071147	Ochotona princeps	95.81	0.00e+00	1373.00
IUUC-Ont-071351	Oreochromis niloticus	95.38	0.00e+00	1341.00
IUUC-Oan-073335	Ornithorhynchus anatinus	96.74	0.00e+00	1394.00
IUUC-Ocu-074072	Oryctolagus cuniculus	96.59	0.00e+00	1392.00
IUUC-Oba-075914	Oryza barthii	78.86	0.00e+00	1205.00
IUUC-Obr-076224	Oryza brachyantha	79.18	0.00e+00	1193.00
IUUC-Ogl-077282	Oryza glaberrima	78.36	0.00e+00	1201.00
IUUC-Ogu-078174	Oryza glumaepatula	78.86	0.00e+00	1205.00
IUUC-Oin-079103	Oryza indica	78.86	0.00e+00	1205.00
IUUC-Olo-080675	Oryza longistaminata	79.00	0.00e+00	1206.00
IUUC-Ome-081247	Oryza meridionalis	78.86	0.00e+00	1206.00
IUUC-Oni-082078	Oryza nivara	78.73	0.00e+00	1204.00
IUUC-Opu-083806	Oryza punctata	78.86	0.00e+00	1208.00
IUUC-Oru-084634	Oryza rufipogon	78.86	0.00e+00	1207.00
IUUC-Osa-085960	Oryza sativa	78.86	0.00e+00	1205.00
IUUC-Ola-086382	Oryzias latipes	95.26	0.00e+00	1341.00
IUUC-Olu-087839	Ostreococcus lucimarinus	76.90	0.00e+00	1161.00
IUUC-Oga-088037	Otolemur garnettii	96.33	0.00e+00	1383.00
IUUC-Oar-089684	Ovis aries	96.73	0.00e+00	1397.00
IUUC-Ptr-091378	Pan troglodytes	96.59	0.00e+00	1392.00
IUUC-Pan-092849	Papio anubis	96.59	0.00e+00	1392.00
IUUC-Pma-094537	Petromyzon marinus	85.50	0.00e+00	654.00
IUUC-Pno-094915	Phaeosphaeria nodorum	74.93	0.00e+00	1040.00
IUUC-Ppa-095632	Physcomitrella patens	78.04	0.00e+00	1154.00
IUUC-Pfo-097440	Poecilia formosa	95.38	0.00e+00	1338.00
IUUC-Pab-098469	Pongo abelii	96.59	0.00e+00	1392.00
IUUC-Pop-100047	Populus trichocarpa	78.73	0.00e+00	1206.00
IUUC-Pca-100399	Procavia capensis	91.87	0.00e+00	1295.00
IUUC-Ppe-101767	Prunus persica	77.33	0.00e+00	1200.00
IUUC-Pva-102426	Pteropus vampyrus	95.81	0.00e+00	1348.00
IUUC-Pgr-103599	Puccinia graminis	74.29	0.00e+00	1144.00
IUUC-Ptt-103740	Puccinia triticina	74.42	0.00e+00	1145.00
IUUC-Pte-104030	Pyrenophora teres	72.40	0.00e+00	1073.00
IUUC-Pyt-104541	Pyrenophora triticirepentis	72.40	0.00e+00	1073.00
IUUC-Rno-105144	Rattus norvegicus	96.59	0.00e+00	1392.00
IUUC-Sce-106244	Saccharomyces cerevisiae	69.22	0.00e+00	1009.00
IUUC-Sha-106589	Sarcophilus harrisii	97.11	0.00e+00	1398.00
IUUC-Sja-107673	Schizosaccharomyces japonicus	70.83	0.00e+00	1057.00
IUUC-Spo-108247	Schizosaccharomyces pombe	71.17	0.00e+00	1034.00
IUUC-Ssl-108642	Sclerotinia sclerotiorum	71.58	0.00e+00	1074.00
IUUC-Smo-108877	Selaginella moellendorffii	78.07	0.00e+00	1189.00
IUUC-Sit-110623	Setaria italica	78.47	0.00e+00	1197.00
IUUC-Sly-111151	Solanum lycopersicum	77.81	0.00e+00	1182.00
IUUC-Stu-111959	Solanum tuberosum	78.31	0.00e+00	1209.00
IUUC-Sar-113021	Sorex araneus	96.85	0.00e+00	1392.00
IUUC-Sbi-114457	Sorghum bicolor	79.13	0.00e+00	1194.00
IUUC-Sre-115052	Sporisorium reilianum	75.58	0.00e+00	1164.00
IUUC-Ssc-116293	Sus scrofa	96.21	0.00e+00	1392.00
IUUC-Tgu-116544	Taeniopygia guttata	94.09	0.00e+00	1321.00
IUUC-Tru-117991	Takifugu rubripes	94.90	0.00e+00	951.00
IUUC-Tsy-119131	Tarsius syrichta	97.89	0.00e+00	724.00
IUUC-Tni-120192	Tetraodon nigroviridis	93.80	0.00e+00	1330.00
IUUC-Tca-121502	Theobroma cacao	77.72	0.00e+00	1173.00
IUUC-Tre-122189	Trichoderma reesei	72.20	0.00e+00	1092.00
IUUC-Tvi-122310	Trichoderma virens	71.67	0.00e+00	1077.00
IUUC-Tae-124332	Triticum aestivum	78.78	0.00e+00	1170.00
IUUC-Tur-126733	Triticum urartu	78.51	0.00e+00	1152.00
IUUC-Tme-127147	Tuber melanosporum	72.04	0.00e+00	1066.00
IUUC-Tbe-127255	Tupaia belangeri	89.14	0.00e+00	1282.00
IUUC-Ttr-128876	Tursiops truncatus	96.32	0.00e+00	1382.00
IUUC-Uma-129448	Ustilago maydis	75.81	0.00e+00	1159.00
IUUC-Vda-129800	Verticillium dahliae	71.37	0.00e+00	1072.00
IUUC-Vpa-130573	Vicugna pacos	98.82	0.00e+00	825.00
IUUC-Vvi-131622	Vitis vinifera	79.00	0.00e+00	1207.00
IUUC-Xtr-132458	Xenopus tropicalis	96.84	0.00e+00	1325.00
IUUC-Xma-134045	Xiphophorus maculatus	95.38	0.00e+00	1338.00
IUUC-Yli-134382	Yarrowia lipolytica	71.37	0.00e+00	1096.00
IUUC-Zma-134817	Zea mays	78.86	0.00e+00	1204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence