iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054044

UUCD1 version

UUC-LoA-00815

Ensembl Protein ID

ENSLAFP00000023213.1

UniProt Accession

G3U5V5; G3U5V5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003001.4	ENSLAFT00000034141.1	ENSLAFP00000023213.1
ENSLAFG00000003001.4	ENSLAFT00000003005.4	ENSLAFP00000002505.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-58	191.9	1703	1735
UBD/Beta-Prp	9.80e-123	409.4	56	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htd.svtclaf.sd.tllvsGsdDgtikvWDlr 31
           H d ++++la  ++ ++++s++ Dgt+++WD+ 
   Q: 1703 HVDgPIWGLAThPSrDFFLSAAEDGTVRLWDIA 1735
           5553699999898889***************75 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgs..rdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcv 87
           +++gh ++ i+ ++ +p++ l+atg   +   i vwd  t ++++ l   h+ +++++ f+ dg+ lv+++ D  ++++vwd + gk++
   Q: 56   FYRGHSDDIIS-LALHPERVLVATGQvgKEPYICVWDSYTVQTISVLkDVHTHGIACLAFDLDGQRLVSVGLDskNAVCVWDWKRGKML 143
           67889999999.9999********96115567***************777*************************************** PP
   S: 88   htlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkll 172
           +   gh+d++ ++s++ +  +klvs + ++ i+ w l  +    +  ++ ++ ++ +++++ +    l  sG+l++ + +W+    +l+
   Q: 144  SMAPGHTDRIFDISWDLYLpNKLVSCG-VKHIKFWSLCGNALTPKrgVFGKTGDLQTILCLACARdELTYSGALNGDIYVWKG--INLI 229
           *****************9967777776.*********999999999955555555555555555559**************66..9*** PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
           rt +g+ht  + s++  ++g  +++g++dg ++lwdl 
   Q: 230  RTIQGAHTAGIFSMNACEEG--FATGGRDGCIRLWDLT 265
           ***************99965..**************96 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCC GGAGCGCCCC GAGCTGCCAC CTGCGGCTCG AGTGGGTGTA CGGCTACCGG 60
GGCCACCAGT GCCGCAACAA CCTCTACTAC ACGGCGGCCA AGGAGATCGT GTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	95.20	0.00e+00	3797.00
IUUC-Apl-003360	Anas platyrhynchos	89.78	0.00e+00	3526.00
IUUC-Ame-011681	Astyanax mexicanus	83.98	0.00e+00	3484.00
IUUC-Bta-012838	Bos taurus	95.10	0.00e+00	3841.00
IUUC-Cja-019068	Callithrix jacchus	95.25	0.00e+00	3830.00
IUUC-Cfa-020531	Canis familiaris	94.90	0.00e+00	3858.00
IUUC-Cpo-022304	Cavia porcellus	92.02	0.00e+00	3607.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.11	3.00e-100	362.00
IUUC-Csa-023621	Chlorocebus sabaeus	94.51	0.00e+00	3495.00
IUUC-Dre-028772	Danio rerio	83.79	0.00e+00	3486.00
IUUC-Dno-030063	Dasypus novemcinctus	93.80	0.00e+00	3777.00
IUUC-Dor-030980	Dipodomys ordii	85.52	0.00e+00	1560.00
IUUC-Ete-032554	Echinops telfairi	93.24	0.00e+00	1044.00
IUUC-Eca-033909	Equus caballus	95.60	0.00e+00	3548.00
IUUC-Eeu-035180	Erinaceus europaeus	78.26	0.00e+00	1462.00
IUUC-Fal-037219	Ficedula albicollis	89.92	0.00e+00	3656.00
IUUC-Gmo-039146	Gadus morhua	79.71	0.00e+00	3284.00
IUUC-Gga-041095	Gallus gallus	89.70	0.00e+00	2634.00
IUUC-Gac-041341	Gasterosteus aculeatus	81.88	0.00e+00	3361.00
IUUC-Hsa-045997	Homo sapiens	95.76	0.00e+00	3845.00
IUUC-Lch-050306	Latimeria chalumnae	84.17	0.00e+00	3156.00
IUUC-Loc-052215	Lepisosteus oculatus	84.19	0.00e+00	3517.00
IUUC-Mcc-054733	Macaca mulatta	95.61	0.00e+00	3842.00
IUUC-Mga-059666	Meleagris gallopavo	88.86	0.00e+00	3484.00
IUUC-Mmr-060995	Microcebus murinus	95.66	0.00e+00	3832.00
IUUC-Mdo-062482	Monodelphis domestica	91.92	0.00e+00	3741.00
IUUC-Mmu-063533	Mus musculus	94.29	0.00e+00	3777.00
IUUC-Mpu-066704	Mustela putorius furo	95.35	0.00e+00	3850.00
IUUC-Mlu-067592	Myotis lucifugus	94.60	0.00e+00	3801.00
IUUC-Nle-069911	Nomascus leucogenys	95.35	0.00e+00	3830.00
IUUC-Ont-071966	Oreochromis niloticus	83.67	0.00e+00	3474.00
IUUC-Ola-086738	Oryzias latipes	83.02	0.00e+00	3430.00
IUUC-Oga-088436	Otolemur garnettii	93.40	0.00e+00	3746.00
IUUC-Oar-090153	Ovis aries	95.00	0.00e+00	3704.00
IUUC-Ptr-091008	Pan troglodytes	95.46	0.00e+00	3820.00
IUUC-Pan-092404	Papio anubis	95.25	0.00e+00	3820.00
IUUC-Psi-093417	Pelodiscus sinensis	89.62	0.00e+00	3512.00
IUUC-Ppa-095656	Physcomitrella patens	24.16	1.00e-17	86.30
IUUC-Pfo-096073	Poecilia formosa	83.74	0.00e+00	3476.00
IUUC-Pab-097900	Pongo abelii	95.05	0.00e+00	3821.00
IUUC-Pca-100107	Procavia capensis	81.53	0.00e+00	2548.00
IUUC-Pva-102880	Pteropus vampyrus	91.70	0.00e+00	3501.00
IUUC-Rno-106084	Rattus norvegicus	94.55	0.00e+00	3839.00
IUUC-Sha-106974	Sarcophilus harrisii	92.09	0.00e+00	3744.00
IUUC-Sar-113401	Sorex araneus	85.10	0.00e+00	934.00
IUUC-Ssc-116057	Sus scrofa	95.16	0.00e+00	3752.00
IUUC-Tru-118444	Takifugu rubripes	82.31	0.00e+00	3390.00
IUUC-Tsy-118941	Tarsius syrichta	83.74	0.00e+00	2809.00
IUUC-Tni-120683	Tetraodon nigroviridis	81.89	0.00e+00	3242.00
IUUC-Tbe-127467	Tupaia belangeri	86.83	0.00e+00	1833.00
IUUC-Ttr-129138	Tursiops truncatus	91.17	0.00e+00	3511.00
IUUC-Vpa-130083	Vicugna pacos	89.50	0.00e+00	3412.00
IUUC-Xtr-131835	Xenopus tropicalis	87.25	0.00e+00	3615.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence