iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-30	103.2	213	246
UBD/Beta-Prp	1.80e-44	152.1	3	109

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H+  +  ++f +d +ll++ s+Dgt+ +W ++++
   Q: 213  HSRYILRCKFsPDsRLLLTTSGDGTVCIWKTDDF 246
           99999999***999***************98776 PP

UBD/Beta-Prp

   S: 146  hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec...vrtlnghtdnvksvrfspnderlvsg 240
           ++++ +l++G++D t+++W+  tg++++t++   t++v+ l+ ++++++l+++++ + ++l+dl+++ c   v  + g ++nv+++ f ++++++ ++
   Q: 3    DQQQLILATGGYDHTIKVWQAHTGNCIKTMRFVETSQVNALDRTPDKTRLAACGY-QCIRLYDLESN-CtapVINFDGVQKNVTRLGFQEDGNWMFTA 98
           5667899***********************************************9.58******965.4355999*********************** PP
   S: 241  ssDgsiriWdl 251
           ++D  +riWd+
   Q: 99   GEDHHVRIWDM 109
           *********96 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGDQQQLILA TGGYDHTIKV WQAHTGNCIK TMRFVETSQV NALDRTPDKT RLAACGYQCI 60
RLYDLESNCT APVINFDGVQ KNVTRLGFQE DGNWMFTAGE DHHVRIWDMI AAPPHCSRIF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTATCGAGG ACCAATGGAC CGATAGGTCT GGTGAAATGA AAACATTGGG GCAAAAAAAC 60
GCGGAAATTG TCAATTAATC TGTGCAATCA CAGGATGGGG GACCAACAGC AGCTGATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031931--C:TORC1 complex
GO:0031932--C:TORC2 complex
GO:0045793--P:positive regulation of cell size
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0031929--P:TOR signaling

KEGG

dme:Dmel_CG3004

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000595	Aegilops tauschii	44.52	1.00e-73	268.00
IUUC-Aml-001813	Ailuropoda melanoleuca	48.89	1.00e-92	332.00
IUUC-Atr-002512	Amborella trichopoda	43.55	5.00e-74	270.00
IUUC-Apl-003495	Anas platyrhynchos	48.24	1.00e-78	285.00
IUUC-Aca-004613	Anolis carolinensis	51.11	1.00e-96	345.00
IUUC-Aly-006340	Arabidopsis lyrata	42.48	3.00e-71	261.00
IUUC-Ath-007273	Arabidopsis thaliana	42.16	2.00e-70	258.00
IUUC-Ago-007737	Ashbya gossypii	40.13	7.00e-64	236.00
IUUC-Acl-008090	Aspergillus clavatus	40.17	2.00e-41	162.00
IUUC-Afl-008490	Aspergillus flavus	37.88	1.00e-30	126.00
IUUC-Afu-009060	Aspergillus fumigatus	39.04	2.00e-35	142.00
IUUC-Ani-009251	Aspergillus nidulans	39.67	6.00e-41	160.00
IUUC-Ang-009528	Aspergillus niger	38.73	8.00e-53	199.00
IUUC-Aor-010005	Aspergillus oryzae	38.93	2.00e-48	184.00
IUUC-Ate-010423	Aspergillus terreus	40.59	6.00e-42	164.00
IUUC-Ame-011752	Astyanax mexicanus	50.48	2.00e-95	341.00
IUUC-Bgr-012299	Blumeria graminis	37.30	5.00e-52	197.00
IUUC-Bta-013007	Bos taurus	50.16	1.00e-91	328.00
IUUC-Bci-013987	Botrytis cinerea	38.22	8.00e-58	216.00
IUUC-Bdi-014082	Brachypodium distachyon	44.52	9.00e-74	269.00
IUUC-Bol-015088	Brassica oleracea	42.16	1.00e-70	258.00
IUUC-Bra-016682	Brassica rapa	37.76	8.00e-61	226.00
IUUC-Cel-018473	Caenorhabditis elegans	27.16	2.00e-34	139.00
IUUC-Cja-019216	Callithrix jacchus	47.57	2.00e-74	271.00
IUUC-Cfa-021229	Canis familiaris	49.21	2.00e-93	334.00
IUUC-Cpo-022270	Cavia porcellus	49.21	2.00e-93	334.00
IUUC-Cre-022742	Chlamydomonas reinhardtii	42.39	3.00e-74	270.00
IUUC-Csa-023275	Chlorocebus sabaeus	49.21	3.00e-93	333.00
IUUC-Cin-025588	Ciona intestinalis	47.63	2.00e-88	318.00
IUUC-Csv-026252	Ciona savignyi	48.41	3.00e-89	320.00
IUUC-Cgl-026418	Colletotrichum gloeosporioides	38.85	4.00e-56	210.00
IUUC-Cne-027013	Cryptococcus neoformans	39.68	2.00e-60	224.00
IUUC-Cme-027131	Cyanidioschyzon merolae	31.02	1.00e-47	182.00
IUUC-Dre-028424	Danio rerio	50.79	3.00e-96	343.00
IUUC-Dno-029327	Dasypus novemcinctus	49.21	2.00e-93	334.00
IUUC-Dor-030186	Dipodomys ordii	53.02	4.00e-47	181.00
IUUC-Dse-031475	Dothistroma septosporum	37.43	4.00e-56	210.00
IUUC-Ete-032252	Echinops telfairi	40.50	7.00e-60	223.00
IUUC-Eca-033889	Equus caballus	47.03	3.00e-64	237.00
IUUC-Fca-035989	Felis catus	49.21	2.00e-93	334.00
IUUC-Fal-036637	Ficedula albicollis	50.79	8.00e-97	345.00
IUUC-Fox-038066	Fusarium oxysporum	39.05	2.00e-56	211.00
IUUC-Fso-038288	Fusarium solani	37.46	4.00e-51	194.00
IUUC-Gmo-039477	Gadus morhua	50.48	2.00e-95	341.00
IUUC-Ggr-039990	Gaeumannomyces graminis	39.68	8.00e-57	213.00
IUUC-Gga-040890	Gallus gallus	50.79	6.00e-97	346.00
IUUC-Gac-041502	Gasterosteus aculeatus	50.48	3.00e-95	340.00
IUUC-Gma-043580	Glycine max	44.19	2.00e-73	268.00
IUUC-Ggo-045629	Gorilla gorilla	49.05	2.00e-93	334.00
IUUC-Hsa-045824	Homo sapiens	48.08	9.00e-81	292.00
IUUC-Hvu-047767	Hordeum vulgare	44.19	2.00e-73	268.00
IUUC-Itr-047932	Ictidomys tridecemlineatus	49.21	2.00e-93	334.00
IUUC-Kpa-049173	Komagataella pastoris	42.11	3.00e-67	247.00
IUUC-Lch-049703	Latimeria chalumnae	51.11	6.00e-97	346.00
IUUC-Lpe-050744	Leersia perrieri	40.97	6.00e-64	236.00
IUUC-Loc-052507	Lepisosteus oculatus	50.79	2.00e-96	344.00
IUUC-Lma-053084	Leptosphaeria maculans	37.35	1.00e-53	202.00
IUUC-Laf-053595	Loxodonta africana	49.21	2.00e-93	335.00
IUUC-Mcc-055634	Macaca mulatta	41.58	5.00e-83	300.00
IUUC-Meu-055925	Macropus eugenii	50.54	6.00e-84	303.00
IUUC-Mor-057131	Magnaporthe oryzae	38.85	9.00e-60	223.00
IUUC-Mpo-057524	Magnaporthe poae	40.63	2.00e-57	214.00
IUUC-Mtr-057980	Medicago truncatula	43.87	2.00e-73	268.00
IUUC-Mla-059082	Melampsora laricipopulina	35.38	1.00e-50	192.00
IUUC-Mga-059552	Meleagris gallopavo	49.12	1.00e-79	288.00
IUUC-Mvi-060504	Microbotryum violaceum	39.03	7.00e-58	217.00
IUUC-Mdo-062886	Monodelphis domestica	50.48	3.00e-96	344.00
IUUC-Mmu-063477	Mus musculus	49.21	3.00e-93	334.00
IUUC-Mac-065439	Musa acuminata	44.52	2.00e-73	268.00
IUUC-Mpu-066708	Mustela putorius furo	48.89	2.00e-92	331.00
IUUC-Mlu-067311	Myotis lucifugus	47.69	2.00e-92	331.00
IUUC-Nfi-068294	Neosartorya fischeri	38.84	2.00e-36	145.00
IUUC-Ncr-068811	Neurospora crassa	38.41	1.00e-53	202.00
IUUC-Nle-069632	Nomascus leucogenys	49.21	3.00e-93	333.00
IUUC-Opr-071128	Ochotona princeps	51.12	6.00e-55	205.00
IUUC-Ont-071494	Oreochromis niloticus	50.79	6.00e-96	342.00
IUUC-Oan-073298	Ornithorhynchus anatinus	45.50	1.00e-47	181.00
IUUC-Ocu-073983	Oryctolagus cuniculus	48.89	4.00e-92	330.00
IUUC-Oba-076001	Oryza barthii	40.65	2.00e-63	234.00
IUUC-Obr-076833	Oryza brachyantha	43.23	2.00e-72	265.00
IUUC-Ogl-077680	Oryza glaberrima	43.55	2.00e-72	265.00
IUUC-Ogu-078086	Oryza glumaepatula	40.65	5.00e-63	233.00
IUUC-Oin-079336	Oryza indica	43.55	2.00e-72	265.00
IUUC-Olo-080368	Oryza longistaminata	39.64	3.00e-53	200.00
IUUC-Oni-083046	Oryza nivara	40.65	2.00e-63	234.00
IUUC-Opu-084173	Oryza punctata	40.65	2.00e-63	234.00
IUUC-Oru-084599	Oryza rufipogon	40.65	2.00e-63	234.00
IUUC-Osa-086193	Oryza sativa	43.55	2.00e-72	265.00
IUUC-Ola-087216	Oryzias latipes	50.48	6.00e-96	342.00
IUUC-Olu-087852	Ostreococcus lucimarinus	41.04	9.00e-70	256.00
IUUC-Oga-088840	Otolemur garnettii	49.05	4.00e-93	333.00
IUUC-Oar-089294	Ovis aries	49.82	1.00e-81	295.00
IUUC-Ptr-090565	Pan troglodytes	49.21	3.00e-93	333.00
IUUC-Pan-092175	Papio anubis	49.21	3.00e-93	333.00
IUUC-Psi-093180	Pelodiscus sinensis	50.00	4.00e-81	293.00
IUUC-Pma-094705	Petromyzon marinus	47.94	8.00e-89	319.00
IUUC-Pno-095001	Phaeosphaeria nodorum	35.42	1.00e-46	179.00
IUUC-Ppa-095628	Physcomitrella patens	46.58	3.00e-77	280.00
IUUC-Pfo-097128	Poecilia formosa	50.48	7.00e-96	342.00
IUUC-Pab-098386	Pongo abelii	49.21	3.00e-93	333.00
IUUC-Pop-099064	Populus trichocarpa	43.87	4.00e-74	270.00
IUUC-Pca-100971	Procavia capensis	49.46	6.00e-82	296.00
IUUC-Ppe-101871	Prunus persica	44.41	2.00e-74	271.00
IUUC-Pva-102230	Pteropus vampyrus	40.14	4.00e-56	211.00
IUUC-Pgr-103511	Puccinia graminis	35.80	2.00e-50	192.00
IUUC-Ptt-103882	Puccinia triticina	34.26	5.00e-47	181.00
IUUC-Pte-104402	Pyrenophora teres	37.05	1.00e-53	202.00
IUUC-Pyt-104448	Pyrenophora triticirepentis	37.05	1.00e-53	202.00
IUUC-Rno-104880	Rattus norvegicus	48.89	1.00e-92	332.00
IUUC-Sce-106266	Saccharomyces cerevisiae	42.11	1.00e-65	242.00
IUUC-Sha-106966	Sarcophilus harrisii	50.48	3.00e-96	344.00
IUUC-Sja-107797	Schizosaccharomyces japonicus	44.01	4.00e-71	260.00
IUUC-Spo-108366	Schizosaccharomyces pombe	44.34	6.00e-71	259.00
IUUC-Smo-108749	Selaginella moellendorffii	43.41	9.00e-71	259.00
IUUC-Sit-110741	Setaria italica	44.19	3.00e-73	267.00
IUUC-Sly-111879	Solanum lycopersicum	42.11	6.00e-51	192.00
IUUC-Sbi-114551	Sorghum bicolor	44.19	7.00e-73	266.00
IUUC-Sre-114962	Sporisorium reilianum	34.99	3.00e-55	207.00
IUUC-Ssc-115363	Sus scrofa	48.42	1.00e-92	332.00
IUUC-Tgu-116695	Taeniopygia guttata	39.26	1.00e-63	236.00
IUUC-Tru-117999	Takifugu rubripes	49.21	2.00e-93	334.00
IUUC-Tni-119973	Tetraodon nigroviridis	49.52	6.00e-95	339.00
IUUC-Tca-121688	Theobroma cacao	43.73	5.00e-74	270.00
IUUC-Tre-122158	Trichoderma reesei	37.66	2.00e-52	198.00
IUUC-Tvi-122511	Trichoderma virens	38.99	7.00e-56	209.00
IUUC-Tae-124124	Triticum aestivum	44.52	2.00e-73	268.00
IUUC-Tur-126228	Triticum urartu	41.61	1.00e-64	238.00
IUUC-Tme-127100	Tuber melanosporum	42.30	5.00e-66	243.00
IUUC-Ttr-128216	Tursiops truncatus	46.39	1.00e-19	89.40
IUUC-Uma-129358	Ustilago maydis	35.69	1.00e-55	209.00
IUUC-Vda-129756	Verticillium dahliae	38.10	1.00e-55	208.00
IUUC-Vvi-131283	Vitis vinifera	44.19	1.00e-73	268.00
IUUC-Xtr-132363	Xenopus tropicalis	50.16	8.00e-95	339.00
IUUC-Xma-133857	Xiphophorus maculatus	50.48	7.00e-96	342.00
IUUC-Yli-134368	Yarrowia lipolytica	42.43	5.00e-65	240.00
IUUC-Zma-135854	Zea mays	44.19	8.00e-73	266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence