iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074772

Ensembl Protein ID

ENSOCUP00000009000.2

UniProt Accession

G1SZA9; G1SZA9_RABIT

Genbank Protein ID

ENSOCUP00000009000

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02008165

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010446.3	ENSOCUT00000010450.2	ENSOCUP00000009000.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-29	99.5	299	334
UBD/Beta-Prp	1.20e-45	156.0	297	581

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D+ i++W++  g+l
   Q: 299  HLSEVNAVCFgPNsSLLATGGADHLIHLWNVVGGRL 334
           99*********7779***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           ++h s +++v+f p++sllatg++d+ i +w+v  g l +    +  + +t+v+f+p+g+  + +   +++++w +   +   tl+gh+
   Q: 297  DAHLSEVNAVCFGPNSSLLATGGADHLIHLWNVVGGRLEANQtLEGAGSITSVDFDPSGSQVLAATYNQAAQLWKVGEAQSKETLSGHK 385
           6788999*******************************5554488899************9999999********************** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           d+v++ +f  +++  v+Gs+drt++ wdl   +c + t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +d+v
   Q: 386  DKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCAR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPRCTQIIP--VQDRV 468
           ***********************************9.666655...5555555556*************************6..599** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +sls+++++ +l+s+s+d t+k+ dl+++++ + +++       d++k   fsp+  + + gs Dg ++iWd+++g l + l +++   
   Q: 469  TSLSLSHDQLHLLSCSRDDTLKVIDLRASNVRQVFRAEGfkcgsDWTK-AVFSPDRSYALAGSWDGALYIWDVDTGRLESRLRGPHGAA 556
           ***************************999955555554445526666.8899*********************************999 PP
   S: 268  isvavlsfgdnvlvlgsedskvniw 292
           +   +++++++++v++++  kv +w
   Q: 557  VNAVAWCYSGSHVVSVDQGRKVVLW 581
           999999************99**999 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

LVPPDNRLLE KAELLATLSE RLQPEPGDVS PAAPPSPEEE SGRGSEQAPR PAALREKWQQ 60
EEEELRLVCG EMAYQVVEKS AALGTLEAEL EERQSRLAAL EARVAQLQEA RAQKEAQVED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGTGCCTC CAGATAACCG TCTCCTGGAG AAGGCCGAGC TGCTGGCCAC GCTGTCTGAG 60
AGGCTGCAGC CAGAACCAGG CGATGTCAGC CCCGCCGCGC CCCCGAGCCC CTGGTGAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	65.71	0.00e+00	655.00
IUUC-Atr-003073	Amborella trichopoda	32.67	4.00e-28	119.00
IUUC-Aca-004664	Anolis carolinensis	70.00	9.00e-96	342.00
IUUC-Ame-011152	Astyanax mexicanus	45.22	3.00e-107	382.00
IUUC-Bta-013118	Bos taurus	83.05	0.00e+00	832.00
IUUC-Cja-020002	Callithrix jacchus	84.52	0.00e+00	844.00
IUUC-Cfa-020878	Canis familiaris	80.10	0.00e+00	810.00
IUUC-Cpo-022476	Cavia porcellus	81.30	0.00e+00	799.00
IUUC-Csa-024134	Chlorocebus sabaeus	83.45	0.00e+00	834.00
IUUC-Cho-024853	Choloepus hoffmanni	69.07	7.00e-168	583.00
IUUC-Dre-027949	Danio rerio	44.04	4.00e-118	418.00
IUUC-Dno-029683	Dasypus novemcinctus	84.47	0.00e+00	762.00
IUUC-Dor-030897	Dipodomys ordii	77.36	0.00e+00	836.00
IUUC-Ete-032957	Echinops telfairi	91.24	5.00e-127	448.00
IUUC-Eca-033303	Equus caballus	91.05	2.00e-166	578.00
IUUC-Eeu-035336	Erinaceus europaeus	72.21	4.00e-147	514.00
IUUC-Fca-036232	Felis catus	84.10	0.00e+00	894.00
IUUC-Gmo-038880	Gadus morhua	53.50	2.00e-68	253.00
IUUC-Gac-042500	Gasterosteus aculeatus	43.75	5.00e-81	295.00
IUUC-Ggo-045130	Gorilla gorilla	90.07	0.00e+00	672.00
IUUC-Hsa-046359	Homo sapiens	85.27	0.00e+00	822.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	84.42	0.00e+00	885.00
IUUC-Lch-050669	Latimeria chalumnae	53.01	4.00e-94	337.00
IUUC-Laf-053699	Loxodonta africana	83.45	0.00e+00	836.00
IUUC-Mcc-055657	Macaca mulatta	79.25	0.00e+00	740.00
IUUC-Meu-056639	Macropus eugenii	49.02	8.00e-106	377.00
IUUC-Mmr-061314	Microcebus murinus	75.93	0.00e+00	758.00
IUUC-Mdo-061841	Monodelphis domestica	65.58	0.00e+00	652.00
IUUC-Mmu-064065	Mus musculus	80.95	0.00e+00	875.00
IUUC-Mpu-066742	Mustela putorius furo	82.53	0.00e+00	823.00
IUUC-Mlu-067019	Myotis lucifugus	85.61	0.00e+00	653.00
IUUC-Nle-069037	Nomascus leucogenys	85.62	0.00e+00	863.00
IUUC-Opr-071039	Ochotona princeps	84.59	0.00e+00	852.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.60	4.00e-137	480.00
IUUC-Ola-086964	Oryzias latipes	52.96	8.00e-82	296.00
IUUC-Oga-088188	Otolemur garnettii	82.71	0.00e+00	783.00
IUUC-Oar-090231	Ovis aries	78.22	0.00e+00	835.00
IUUC-Ptr-091434	Pan troglodytes	82.25	0.00e+00	775.00
IUUC-Pan-091868	Papio anubis	84.42	0.00e+00	822.00
IUUC-Psi-093652	Pelodiscus sinensis	62.65	9.00e-159	553.00
IUUC-Pfo-096960	Poecilia formosa	45.00	1.00e-88	320.00
IUUC-Pab-097776	Pongo abelii	84.42	0.00e+00	778.00
IUUC-Pca-100220	Procavia capensis	73.25	7.00e-82	298.00
IUUC-Pva-103135	Pteropus vampyrus	86.01	0.00e+00	794.00
IUUC-Rno-105529	Rattus norvegicus	80.44	0.00e+00	875.00
IUUC-Sha-107062	Sarcophilus harrisii	65.01	0.00e+00	702.00
IUUC-Sar-113109	Sorex araneus	81.42	2.00e-99	356.00
IUUC-Ssc-115271	Sus scrofa	84.47	0.00e+00	829.00
IUUC-Ttr-128267	Tursiops truncatus	80.14	0.00e+00	796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence