iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	TargetScan
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
InWeb_IM
Protein 3D Structure
PDB	MMDB
Disease-associated Information
GWASdb	OMIM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	BioGRID
mUbiSiDa
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Other/Other	UBD/Other/Other	20440844
ULD/UDP/UBQ/UBQ_Other	UBQ_Other	12507522; 15987890

Classification

Family	E-value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	6.30e-12	46.9	153	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           q++++ ++g++l+l v ++dtV  +K++++ ++g+ p +qr+ ++G++L d  ++ +++++ ++++ ++++++
   Q: 153  QLRLRLSTGKDLKLVVRSTDTVFHMKRRLHAAEGVEPGSQRWFFSGRPLTDKMKFEELKIPKDYVVQVIVSQP 225
           7899*****************************************************************9987 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MGGCVGAQHD SSGSLNENSE GTGVALGRNQ PLKKEKPKWK SDYPMTDGQL RSKRDEFWDT 60
APAFEGRKEI WDALKAAAHA FESNDHELAQ AIIDGANITL PHGALTECYD ELGNRYQLPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCGCGG GCCGGGGGCC GATGGGTCCT GGCGGACGCG AGGCGCCGGC GCGGGGCTCG 60
CCTGGACTCG GGTGTGCGGG GCTGTGAGGG GGCGAGGCGG GCGCTGCGGC CCGCCCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR032752--UBD
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF16455--UBD
PF00240--ubiquitin

Gene Ontology

GO:0005737--C:cytoplasm

KEGG

hsa:92181

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000911	Aegilops tauschii	50.56	3.00e-21	93.60
IUUC-Aml-002013	Ailuropoda melanoleuca	97.63	2.00e-123	434.00
IUUC-Atr-003109	Amborella trichopoda	48.10	1.00e-16	78.60
IUUC-Apl-003537	Anas platyrhynchos	94.31	9.00e-120	422.00
IUUC-Aca-004312	Anolis carolinensis	91.03	2.00e-129	454.00
IUUC-Aly-005398	Arabidopsis lyrata	50.93	6.00e-25	105.00
IUUC-Ath-007276	Arabidopsis thaliana	50.93	6.00e-25	105.00
IUUC-Acl-008129	Aspergillus clavatus	40.23	2.00e-12	66.20
IUUC-Afl-008454	Aspergillus flavus	36.19	6.00e-11	61.20
IUUC-Afu-008981	Aspergillus fumigatus	44.32	5.00e-14	72.00
IUUC-Ani-009295	Aspergillus nidulans	40.43	4.00e-13	68.90
IUUC-Ang-009706	Aspergillus niger	38.46	7.00e-13	67.80
IUUC-Ate-010381	Aspergillus terreus	27.36	3.00e-09	55.80
IUUC-Ame-010674	Astyanax mexicanus	84.92	5.00e-102	363.00
IUUC-Bgr-012138	Blumeria graminis	30.97	2.00e-08	52.80
IUUC-Bta-012859	Bos taurus	97.01	7.00e-137	479.00
IUUC-Bci-013827	Botrytis cinerea	32.48	8.00e-09	54.30
IUUC-Bdi-014755	Brachypodium distachyon	53.47	9.00e-26	108.00
IUUC-Bol-016137	Brassica oleracea	50.00	2.00e-25	107.00
IUUC-Bra-017141	Brassica rapa	50.00	1.00e-25	107.00
IUUC-Cja-019322	Callithrix jacchus	100.00	6.00e-126	442.00
IUUC-Cfa-020136	Canis familiaris	97.86	6.00e-138	483.00
IUUC-Cpo-021942	Cavia porcellus	97.17	1.00e-122	432.00
IUUC-Cre-022622	Chlamydomonas reinhardtii	42.11	2.00e-17	80.50
IUUC-Csa-023767	Chlorocebus sabaeus	100.00	2.00e-140	490.00
IUUC-Cho-025041	Choloepus hoffmanni	81.90	4.00e-94	336.00
IUUC-Cin-025159	Ciona intestinalis	50.44	9.00e-61	226.00
IUUC-Csv-026202	Ciona savignyi	52.74	8.00e-59	219.00
IUUC-Cgl-026644	Colletotrichum gloeosporioides	34.21	2.00e-09	56.60
IUUC-Cme-027198	Cyanidioschyzon merolae	31.34	2.00e-09	55.50
IUUC-Dre-027483	Danio rerio	84.38	4.00e-116	410.00
IUUC-Dno-029744	Dasypus novemcinctus	96.77	2.00e-88	317.00
IUUC-Dme-032026	Drosophila melanogaster	54.50	9.00e-61	226.00
IUUC-Ete-032349	Echinops telfairi	93.60	2.00e-86	310.00
IUUC-Eca-034220	Equus caballus	97.63	2.00e-123	434.00
IUUC-Eeu-035212	Erinaceus europaeus	92.63	9.00e-106	375.00
IUUC-Fca-036190	Felis catus	96.70	4.00e-123	433.00
IUUC-Fal-036993	Ficedula albicollis	91.90	1.00e-116	412.00
IUUC-Fox-037832	Fusarium oxysporum	25.21	8.00e-13	67.80
IUUC-Fso-038354	Fusarium solani	34.19	1.00e-08	53.50
IUUC-Gga-041210	Gallus gallus	93.59	6.00e-133	466.00
IUUC-Gac-041553	Gasterosteus aculeatus	77.09	3.00e-103	367.00
IUUC-Gma-043237	Glycine max	50.94	6.00e-25	105.00
IUUC-Ggo-045306	Gorilla gorilla	99.53	6.00e-126	442.00
IUUC-Hvu-047469	Hordeum vulgare	52.48	2.00e-25	107.00
IUUC-Itr-048466	Ictidomys tridecemlineatus	97.63	2.00e-122	431.00
IUUC-Lch-050222	Latimeria chalumnae	94.87	4.00e-134	470.00
IUUC-Lpe-051415	Leersia perrieri	44.74	1.00e-23	102.00
IUUC-Loc-052330	Lepisosteus oculatus	91.45	1.00e-130	458.00
IUUC-Lma-053022	Leptosphaeria maculans	32.69	7.00e-09	54.30
IUUC-Laf-054326	Loxodonta africana	98.72	1.00e-138	485.00
IUUC-Mcc-055871	Macaca mulatta	100.00	2.00e-140	490.00
IUUC-Meu-056699	Macropus eugenii	90.48	1.00e-111	395.00
IUUC-Mor-056914	Magnaporthe oryzae	32.79	1.00e-08	54.30
IUUC-Mtr-058114	Medicago truncatula	52.78	1.00e-19	88.20
IUUC-Mga-059546	Meleagris gallopavo	95.29	2.00e-45	173.00
IUUC-Mmr-061414	Microcebus murinus	92.00	8.00e-135	472.00
IUUC-Mdo-062051	Monodelphis domestica	96.15	1.00e-135	475.00
IUUC-Mmu-064256	Mus musculus	97.01	2.00e-136	477.00
IUUC-Mac-064699	Musa acuminata	51.46	3.00e-25	106.00
IUUC-Mpu-066187	Mustela putorius furo	97.37	1.00e-110	391.00
IUUC-Mlu-068186	Myotis lucifugus	96.68	7.00e-123	432.00
IUUC-Nfi-068559	Neosartorya fischeri	44.32	3.00e-14	72.80
IUUC-Nle-069488	Nomascus leucogenys	99.53	6.00e-126	442.00
IUUC-Opr-071115	Ochotona princeps	93.81	7.00e-117	412.00
IUUC-Ont-071496	Oreochromis niloticus	73.62	5.00e-101	360.00
IUUC-Ocu-074225	Oryctolagus cuniculus	97.37	4.00e-110	389.00
IUUC-Oba-075372	Oryza barthii	51.19	1.00e-20	90.90
IUUC-Obr-076560	Oryza brachyantha	48.65	2.00e-24	104.00
IUUC-Ogl-077415	Oryza glaberrima	49.50	7.00e-23	99.00
IUUC-Ogu-078202	Oryza glumaepatula	51.19	1.00e-20	90.90
IUUC-Oin-079839	Oryza indica	49.50	7.00e-23	99.00
IUUC-Olo-080965	Oryza longistaminata	48.86	1.00e-15	74.70
IUUC-Ome-081760	Oryza meridionalis	47.66	5.00e-23	99.80
IUUC-Oni-082835	Oryza nivara	51.19	1.00e-20	90.90
IUUC-Opu-083929	Oryza punctata	49.04	4.00e-23	100.00
IUUC-Oru-084682	Oryza rufipogon	51.19	1.00e-20	90.90
IUUC-Osa-085899	Oryza sativa	49.50	7.00e-23	99.00
IUUC-Ola-086769	Oryzias latipes	73.14	1.00e-102	365.00
IUUC-Olu-087730	Ostreococcus lucimarinus	32.61	5.00e-10	56.60
IUUC-Oga-088348	Otolemur garnettii	97.87	2.00e-136	478.00
IUUC-Oar-089998	Ovis aries	95.26	2.00e-120	424.00
IUUC-Ptr-090886	Pan troglodytes	99.10	3.00e-131	460.00
IUUC-Pan-092886	Papio anubis	100.00	2.00e-140	490.00
IUUC-Psi-092936	Pelodiscus sinensis	91.98	1.00e-117	415.00
IUUC-Pma-094754	Petromyzon marinus	64.85	3.00e-68	251.00
IUUC-Pno-095024	Phaeosphaeria nodorum	22.54	2.00e-06	46.60
IUUC-Ppa-095162	Physcomitrella patens	49.53	7.00e-24	102.00
IUUC-Pfo-097343	Poecilia formosa	74.89	1.00e-103	369.00
IUUC-Pab-097647	Pongo abelii	100.00	2.00e-140	490.00
IUUC-Pop-099605	Populus trichocarpa	51.89	2.00e-19	87.40
IUUC-Pca-100773	Procavia capensis	97.86	9.00e-138	482.00
IUUC-Ppe-101177	Prunus persica	50.94	2.00e-18	84.00
IUUC-Pva-103069	Pteropus vampyrus	96.15	3.00e-134	470.00
IUUC-Pte-104152	Pyrenophora teres	32.18	9.00e-05	42.70
IUUC-Pyt-104589	Pyrenophora triticirepentis	32.18	5.00e-06	45.10
IUUC-Rno-104952	Rattus norvegicus	96.84	4.00e-109	386.00
IUUC-Sha-107112	Sarcophilus harrisii	95.26	6.00e-121	426.00
IUUC-Spo-108250	Schizosaccharomyces pombe	23.15	5.00e-06	44.70
IUUC-Smo-109567	Selaginella moellendorffii	51.02	4.00e-23	99.00
IUUC-Sit-109843	Setaria italica	45.04	1.00e-24	105.00
IUUC-Sly-111092	Solanum lycopersicum	53.47	1.00e-24	104.00
IUUC-Stu-112412	Solanum tuberosum	52.48	4.00e-24	102.00
IUUC-Sbi-114467	Sorghum bicolor	41.98	4.00e-23	99.80
IUUC-Ssc-115412	Sus scrofa	96.21	1.00e-121	428.00
IUUC-Tgu-116739	Taeniopygia guttata	93.84	5.00e-119	419.00
IUUC-Tru-118325	Takifugu rubripes	75.00	2.00e-104	371.00
IUUC-Tsy-118987	Tarsius syrichta	68.10	3.00e-73	266.00
IUUC-Tni-119770	Tetraodon nigroviridis	73.50	3.00e-100	357.00
IUUC-Tca-121067	Theobroma cacao	48.67	2.00e-18	84.30
IUUC-Tre-121871	Trichoderma reesei	33.61	2.00e-09	56.20
IUUC-Tvi-122404	Trichoderma virens	26.89	5.00e-07	48.10
IUUC-Tae-124023	Triticum aestivum	52.48	2.00e-25	107.00
IUUC-Tur-126425	Triticum urartu	56.25	1.00e-18	87.00
IUUC-Tme-127068	Tuber melanosporum	33.18	1.00e-20	93.20
IUUC-Tbe-127835	Tupaia belangeri	94.74	4.00e-106	376.00
IUUC-Ttr-128256	Tursiops truncatus	96.58	2.00e-134	471.00
IUUC-Vda-129803	Verticillium dahliae	33.33	1.00e-08	53.90
IUUC-Vvi-131279	Vitis vinifera	49.06	3.00e-18	83.20
IUUC-Xtr-131959	Xenopus tropicalis	92.31	7.00e-131	459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence