iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001697

Ensembl Protein ID

ENSAMEP00000015188.1

UniProt Accession

G1M768; G1M768_AILME

Genbank Protein ID

ENSAMEP00000015188

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01043004

Gene Name

TNIP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014405.1	ENSAMET00000015811.1	ENSAMEP00000015188.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	8.50e-20	70.6	218	274

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           ++ +le+v++L+qQ+ +Yk+DF +ERadREr++++++eL+e v++l +q s+ +d +
   Q: 218  RDTALERVQMLEQQILAYKDDFTSERADRERAQSRIQELEEEVASLRQQASWTQDHR 274
           6789**************************************************976 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

EIERLSEQLE EKEKETQQLM SQPEHAREKE VALLRRSVAE KERARAASDI LCRSLADETH 60
QLRRTLAATA HMCQHLAKCL DERQRTQGDV GEKSPESLCG ENLDLRTTHS CWPERTGGAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATTGAGA GACTTTCTGA GCAACTAGAA GAAAAAGAGA AGGAGACGCA GCAGCTGATG 60
AGCCAGCCGG AGCACGCGCG CGAGAAGGAG GTGGCGCTGC TGCGGAGGAG CGTGGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR015898--G-protein_gamma-like_dom
IPR034735--ZF_CCHC_NOA

PROSITE

PS50058--G_PROTEIN_GAMMA
PS51801--ZF_CCHC_NOA

Pfam

PF12180--EABR

Gene Ontology

GO:0005829--C:cytosol
GO:0005834--C:heterotrimeric G-protein complex
GO:0005634--C:nucleus
GO:0004871--F:signal transducer activity
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0050871--P:positive regulation of B cell activation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043032--P:positive regulation of macrophage activation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003896	Anas platyrhynchos	48.16	2.00e-88	319.00
IUUC-Ame-011223	Astyanax mexicanus	34.09	4.00e-41	162.00
IUUC-Bta-012996	Bos taurus	76.54	4.00e-139	487.00
IUUC-Cja-019376	Callithrix jacchus	66.86	7.00e-123	433.00
IUUC-Cfa-021027	Canis familiaris	85.80	3.00e-168	584.00
IUUC-Cpo-021372	Cavia porcellus	65.68	7.00e-101	360.00
IUUC-Csa-023221	Chlorocebus sabaeus	73.08	7.00e-137	480.00
IUUC-Dre-028604	Danio rerio	36.49	3.00e-48	186.00
IUUC-Dno-029976	Dasypus novemcinctus	67.27	7.00e-55	206.00
IUUC-Dor-030364	Dipodomys ordii	58.94	7.00e-62	231.00
IUUC-Eca-033582	Equus caballus	78.77	2.00e-145	508.00
IUUC-Eeu-034751	Erinaceus europaeus	66.26	1.00e-60	226.00
IUUC-Fca-036086	Felis catus	82.45	1.00e-147	515.00
IUUC-Fal-036828	Ficedula albicollis	49.19	4.00e-95	341.00
IUUC-Gmo-038838	Gadus morhua	35.99	6.00e-35	141.00
IUUC-Gga-041179	Gallus gallus	48.55	1.00e-87	317.00
IUUC-Gac-042266	Gasterosteus aculeatus	36.06	5.00e-38	151.00
IUUC-Ggo-044971	Gorilla gorilla	73.96	3.00e-137	481.00
IUUC-Hsa-045772	Homo sapiens	73.67	7.00e-131	460.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	71.79	1.00e-126	445.00
IUUC-Lch-049851	Latimeria chalumnae	42.94	3.00e-63	236.00
IUUC-Loc-052551	Lepisosteus oculatus	39.34	5.00e-55	208.00
IUUC-Laf-053650	Loxodonta africana	58.26	7.00e-89	320.00
IUUC-Mcc-054744	Macaca mulatta	73.37	3.00e-137	481.00
IUUC-Meu-056799	Macropus eugenii	49.38	1.00e-31	130.00
IUUC-Mga-060124	Meleagris gallopavo	48.24	1.00e-90	327.00
IUUC-Mmr-061466	Microcebus murinus	73.24	7.00e-125	440.00
IUUC-Mdo-062389	Monodelphis domestica	57.38	1.00e-106	380.00
IUUC-Mmu-064000	Mus musculus	71.59	2.00e-135	475.00
IUUC-Mpu-066109	Mustela putorius furo	86.87	7.00e-169	586.00
IUUC-Mlu-067666	Myotis lucifugus	69.35	2.00e-79	288.00
IUUC-Nle-069689	Nomascus leucogenys	73.67	4.00e-137	480.00
IUUC-Opr-070774	Ochotona princeps	57.23	4.00e-72	264.00
IUUC-Ont-072439	Oreochromis niloticus	38.40	5.00e-54	204.00
IUUC-Oan-072817	Ornithorhynchus anatinus	55.19	4.00e-63	234.00
IUUC-Ocu-074621	Oryctolagus cuniculus	64.29	6.00e-85	307.00
IUUC-Olo-080222	Oryza longistaminata	34.38	3.70e+00	25.80
IUUC-Ola-087305	Oryzias latipes	37.04	3.00e-48	186.00
IUUC-Oga-087920	Otolemur garnettii	68.97	3.00e-123	434.00
IUUC-Oar-090351	Ovis aries	67.71	8.00e-21	91.30
IUUC-Ptr-090879	Pan troglodytes	77.14	2.00e-98	352.00
IUUC-Pan-092022	Papio anubis	73.37	2.00e-137	482.00
IUUC-Psi-093302	Pelodiscus sinensis	49.46	4.00e-92	331.00
IUUC-Pno-095083	Phaeosphaeria nodorum	24.58	6.00e-03	37.00
IUUC-Pfo-097250	Poecilia formosa	37.76	2.00e-45	176.00
IUUC-Pab-097929	Pongo abelii	74.27	9.00e-141	492.00
IUUC-Pca-100271	Procavia capensis	66.89	2.00e-40	159.00
IUUC-Pva-102234	Pteropus vampyrus	63.69	1.00e-97	349.00
IUUC-Rno-105850	Rattus norvegicus	71.23	2.00e-138	485.00
IUUC-Sha-107375	Sarcophilus harrisii	55.01	8.00e-98	350.00
IUUC-Ssc-116269	Sus scrofa	77.93	4.00e-144	504.00
IUUC-Tgu-116960	Taeniopygia guttata	48.77	3.00e-92	332.00
IUUC-Tru-118002	Takifugu rubripes	35.14	2.00e-43	170.00
IUUC-Tni-120023	Tetraodon nigroviridis	38.04	7.00e-47	181.00
IUUC-Tbe-127592	Tupaia belangeri	67.90	1.00e-116	412.00
IUUC-Ttr-128362	Tursiops truncatus	69.83	1.00e-120	426.00
IUUC-Vpa-130399	Vicugna pacos	71.79	4.00e-126	444.00
IUUC-Xtr-132677	Xenopus tropicalis	46.59	3.00e-76	278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence