iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	6.00e-20	71.3	290	346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           ++ +le+v++L+qQ+ +Yk+DF++ERadREr++++++eL+e+v +l  qvs+++ds+
   Q: 290  RDTALERVQMLEQQILAYKDDFKSERADRERAHSRIQELEEKVMSLMYQVSQRQDSR 346
           6789***************************************************97 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSSGDARSGR QDEAPSAASA LCGLYHEAGQ QLQLLKDQLA ARDALIASLR TRLAALEGHT 60
APSLVDALLD QVERFREQLR RQEDGASESQ LRQEVERLTE CLEEKEREMQ QLMSQPQHEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCAGGGA GTGGGCGGGG CGGGAAAAGT TCCGGGAAGG CTGGTTATCG CTCCCGCAGC 60
CTAGAGAAGT TGGAGACGCC CAAGTCCCCA CGGAAGGCCC ACAGCTATGT CGTCTGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF12180--EABR

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0050871--P:positive regulation of B cell activation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043032--P:positive regulation of macrophage activation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001697	Ailuropoda melanoleuca	71.09	2.00e-131	461.00
IUUC-Apl-003896	Anas platyrhynchos	47.94	1.00e-93	336.00
IUUC-Ame-011223	Astyanax mexicanus	32.67	3.00e-43	169.00
IUUC-Bta-012996	Bos taurus	74.18	6.00e-130	456.00
IUUC-Bci-013652	Botrytis cinerea	28.21	1.00e+00	29.30
IUUC-Cja-019376	Callithrix jacchus	72.05	6.00e-136	477.00
IUUC-Cfa-021027	Canis familiaris	67.36	7.00e-143	500.00
IUUC-Cpo-021372	Cavia porcellus	66.42	1.00e-112	399.00
IUUC-Csa-023221	Chlorocebus sabaeus	76.87	2.00e-158	551.00
IUUC-Dre-028604	Danio rerio	32.58	2.00e-48	186.00
IUUC-Dno-029976	Dasypus novemcinctus	61.36	3.00e-50	191.00
IUUC-Dor-030364	Dipodomys ordii	57.74	4.00e-63	234.00
IUUC-Eca-033582	Equus caballus	75.20	1.00e-145	509.00
IUUC-Eeu-034751	Erinaceus europaeus	63.21	2.00e-58	218.00
IUUC-Fca-036086	Felis catus	73.55	2.00e-127	448.00
IUUC-Fal-036828	Ficedula albicollis	49.32	1.00e-100	360.00
IUUC-Gmo-038838	Gadus morhua	35.01	2.00e-43	169.00
IUUC-Gga-041179	Gallus gallus	47.38	5.00e-97	348.00
IUUC-Gac-042266	Gasterosteus aculeatus	37.09	2.00e-44	172.00
IUUC-Ggo-044971	Gorilla gorilla	77.80	2.00e-159	555.00
IUUC-Hsa-045772	Homo sapiens	78.27	2.00e-153	535.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	75.67	3.00e-133	467.00
IUUC-Lch-049851	Latimeria chalumnae	42.04	3.00e-69	256.00
IUUC-Loc-052551	Lepisosteus oculatus	37.01	5.00e-62	231.00
IUUC-Laf-053650	Loxodonta africana	57.01	1.00e-86	313.00
IUUC-Mcc-054744	Macaca mulatta	77.34	1.00e-162	565.00
IUUC-Meu-056799	Macropus eugenii	52.29	2.00e-33	136.00
IUUC-Mga-060124	Meleagris gallopavo	46.78	9.00e-93	333.00
IUUC-Mmr-061466	Microcebus murinus	76.85	2.00e-149	521.00
IUUC-Mdo-062389	Monodelphis domestica	58.20	8.00e-117	414.00
IUUC-Mmu-064000	Mus musculus	89.58	0.00e+00	705.00
IUUC-Mpu-066109	Mustela putorius furo	71.90	6.00e-149	520.00
IUUC-Mlu-067666	Myotis lucifugus	62.76	1.00e-71	262.00
IUUC-Nle-069689	Nomascus leucogenys	78.23	3.00e-143	501.00
IUUC-Opr-070774	Ochotona princeps	57.01	6.00e-79	287.00
IUUC-Ont-072439	Oreochromis niloticus	35.67	8.00e-57	214.00
IUUC-Oan-072817	Ornithorhynchus anatinus	53.11	1.00e-58	219.00
IUUC-Ocu-074621	Oryctolagus cuniculus	63.85	1.00e-85	309.00
IUUC-Ola-087305	Oryzias latipes	35.98	6.00e-53	201.00
IUUC-Oga-087920	Otolemur garnettii	69.32	1.00e-139	489.00
IUUC-Oar-090351	Ovis aries	63.16	4.00e-19	85.50
IUUC-Ptr-090879	Pan troglodytes	73.68	6.00e-103	367.00
IUUC-Pan-092022	Papio anubis	77.10	9.00e-159	553.00
IUUC-Psi-093302	Pelodiscus sinensis	47.36	4.00e-102	365.00
IUUC-Pno-095083	Phaeosphaeria nodorum	27.87	3.00e-02	34.70
IUUC-Pfo-097250	Poecilia formosa	35.75	1.00e-49	190.00
IUUC-Pab-097929	Pongo abelii	78.88	2.00e-147	515.00
IUUC-Pca-100271	Procavia capensis	69.08	8.00e-46	177.00
IUUC-Pva-102234	Pteropus vampyrus	65.12	4.00e-115	408.00
IUUC-Sha-107375	Sarcophilus harrisii	54.23	2.00e-105	376.00
IUUC-Ssc-116269	Sus scrofa	73.80	1.00e-143	502.00
IUUC-Tgu-116960	Taeniopygia guttata	52.29	1.00e-96	346.00
IUUC-Tru-118002	Takifugu rubripes	33.79	6.00e-51	194.00
IUUC-Tni-120023	Tetraodon nigroviridis	35.93	3.00e-51	195.00
IUUC-Tre-121983	Trichoderma reesei	24.20	6.00e-01	28.50
IUUC-Tbe-127592	Tupaia belangeri	68.38	2.00e-136	478.00
IUUC-Ttr-128362	Tursiops truncatus	69.14	8.00e-117	413.00
IUUC-Vpa-130399	Vicugna pacos	68.84	4.00e-116	410.00
IUUC-Xtr-132677	Xenopus tropicalis	45.12	1.00e-81	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence