iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089803

Ensembl Protein ID

ENSOARP00000004891.1

UniProt Accession

W5P391; W5P391_SHEEP

Genbank Protein ID

ENSOARP00000004891

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01073627

Gene Name

UBE2E1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004571.1	ENSOART00000004974.1	ENSOARP00000004891.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.70e-50	169.5	51	186

Active Site

Position(s)	Description	Evidence
131	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 51   RIQKELADITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 136
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 137  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 186
           *********************************************99985 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSDDDSRAST SSSSSSSSNQ QTEKEANTPK KKESKVSMSK NSKLLSTSAK RIQKELADIT 60
LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGCGG CCGGGGCCCG AGCCCTCCTG ACAGCGCCCG AGTTCCGTGT CTACACCGGC 60
CTTTCTGTTT TGTCTCCCTC CTCCTGCAGG GGCTGTTTGC GGGGTGGGGC GGGGGGTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

KEGG

oas:101123528

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001532	Ailuropoda melanoleuca	99.43	7.00e-94	335.00
IUUC-Apl-004207	Anas platyrhynchos	98.86	4.00e-93	333.00
IUUC-Aca-005103	Anolis carolinensis	98.86	2.00e-93	334.00
IUUC-Cja-019311	Callithrix jacchus	99.43	9.00e-94	335.00
IUUC-Cfa-020017	Canis familiaris	99.43	9.00e-94	335.00
IUUC-Cpo-022266	Cavia porcellus	99.43	9.00e-94	335.00
IUUC-Csa-023538	Chlorocebus sabaeus	99.43	9.00e-94	335.00
IUUC-Cho-024986	Choloepus hoffmanni	76.27	1.00e-74	271.00
IUUC-Cin-025161	Ciona intestinalis	84.38	1.00e-75	275.00
IUUC-Csv-025982	Ciona savignyi	84.38	3.00e-82	297.00
IUUC-Dre-027449	Danio rerio	87.86	2.00e-83	301.00
IUUC-Dno-029441	Dasypus novemcinctus	100.00	4.00e-75	272.00
IUUC-Dor-030450	Dipodomys ordii	100.00	4.00e-64	235.00
IUUC-Dme-032042	Drosophila melanogaster	87.12	6.00e-83	300.00
IUUC-Ete-032397	Echinops telfairi	97.71	1.00e-100	358.00
IUUC-Eca-033613	Equus caballus	100.00	1.00e-85	308.00
IUUC-Eeu-034691	Erinaceus europaeus	86.86	3.00e-87	314.00
IUUC-Fca-035467	Felis catus	100.00	7.00e-94	335.00
IUUC-Fal-036907	Ficedula albicollis	98.86	2.00e-93	334.00
IUUC-Gmo-039645	Gadus morhua	87.86	8.00e-84	302.00
IUUC-Gga-040403	Gallus gallus	98.86	2.00e-93	334.00
IUUC-Gac-041661	Gasterosteus aculeatus	87.86	1.00e-83	301.00
IUUC-Ggo-045507	Gorilla gorilla	99.43	9.00e-94	335.00
IUUC-Hsa-046576	Homo sapiens	99.43	9.00e-94	335.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	100.00	4.00e-75	272.00
IUUC-Lch-050322	Latimeria chalumnae	95.43	2.00e-98	350.00
IUUC-Loc-052673	Lepisosteus oculatus	89.14	5.00e-86	310.00
IUUC-Laf-054313	Loxodonta africana	99.43	9.00e-94	335.00
IUUC-Mcc-055072	Macaca mulatta	97.90	1.00e-83	301.00
IUUC-Meu-056590	Macropus eugenii	100.00	5.00e-85	305.00
IUUC-Mmr-060791	Microcebus murinus	99.43	9.00e-94	335.00
IUUC-Mmu-063297	Mus musculus	98.86	6.00e-103	365.00
IUUC-Mpu-065698	Mustela putorius furo	100.00	6.00e-104	369.00
IUUC-Mlu-067897	Myotis lucifugus	97.90	1.00e-83	301.00
IUUC-Nle-069622	Nomascus leucogenys	99.43	9.00e-94	335.00
IUUC-Ont-072384	Oreochromis niloticus	91.43	3.00e-95	340.00
IUUC-Oan-073006	Ornithorhynchus anatinus	100.00	5.00e-75	272.00
IUUC-Ocu-074055	Oryctolagus cuniculus	99.43	9.00e-94	335.00
IUUC-Ola-086636	Oryzias latipes	93.53	1.00e-83	302.00
IUUC-Oga-088863	Otolemur garnettii	99.43	9.00e-94	335.00
IUUC-Ptr-090914	Pan troglodytes	99.43	9.00e-94	335.00
IUUC-Pan-092786	Papio anubis	99.43	9.00e-94	335.00
IUUC-Psi-093923	Pelodiscus sinensis	99.43	1.00e-93	335.00
IUUC-Pma-094642	Petromyzon marinus	95.24	5.00e-71	258.00
IUUC-Pfo-096966	Poecilia formosa	91.81	2.00e-83	301.00
IUUC-Pab-098614	Pongo abelii	99.43	9.00e-94	335.00
IUUC-Pva-102561	Pteropus vampyrus	97.90	1.00e-83	301.00
IUUC-Rno-105518	Rattus norvegicus	98.27	8.00e-101	358.00
IUUC-Sha-106897	Sarcophilus harrisii	100.00	1.00e-85	308.00
IUUC-Ssc-115844	Sus scrofa	87.86	3.00e-87	314.00
IUUC-Tgu-116958	Taeniopygia guttata	100.00	3.00e-89	320.00
IUUC-Tru-118531	Takifugu rubripes	93.71	2.00e-80	291.00
IUUC-Tsy-119002	Tarsius syrichta	92.57	8.00e-80	289.00
IUUC-Tni-120349	Tetraodon nigroviridis	94.51	6.00e-82	296.00
IUUC-Tbe-127659	Tupaia belangeri	88.57	2.00e-80	291.00
IUUC-Ttr-128356	Tursiops truncatus	96.00	8.00e-89	318.00
IUUC-Vpa-130232	Vicugna pacos	96.45	2.00e-79	287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence