iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000172869.14	ENST00000311085.8	ENSP00000309690.8
ENSG00000172869.14	ENST00000539542.5	ENSP00000439479.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
RepTar	SomamiR	miRcode	RAID2
Disease-associated Variation
GWASdb	OMIM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PHOSIDA	BioGRID
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-13	52.1	2948	2985

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H ++v ++a  ++  ++v+Gs  g+ik+W+l+t+ ll+
   Q: 2948 HDSPVKAVAVdPTeEYFVTGSAEGNIKIWSLSTFGLLH 2985
           99*********777*******************99987 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MNLHQVLTGA VNPGDHCFSV GSIGDQRFTA YASGCDIVIL GSDFERLQII PGAKHGNIQV 60
GCVDCSMQQG KIAASYGNVI SIFEPVNLPK QKKNLELYSQ WQKSGQFFLE SIAHNITWDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAATGAAA ACCTTGTTCT TTTTAGTTAG TACATGTTCT GTTAGTATAA ATTTATAGTG 60
ACAGAACTAA TAAAACTCTG GGACCTTGCC CTAAGAGTAC ATGTAACATA ATGTAAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR022033--Rav1p_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12234--Rav1p_C
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001368	Ailuropoda melanoleuca	92.69	0.00e+00	5584.00
IUUC-Atr-002754	Amborella trichopoda	23.72	1.00e-18	88.20
IUUC-Apl-003377	Anas platyrhynchos	76.45	0.00e+00	4510.00
IUUC-Aca-004649	Anolis carolinensis	74.36	0.00e+00	4342.00
IUUC-Aly-006404	Arabidopsis lyrata	31.25	8.00e-32	134.00
IUUC-Ath-006612	Arabidopsis thaliana	31.82	4.00e-30	128.00
IUUC-Ang-009742	Aspergillus niger	29.41	1.00e-38	155.00
IUUC-Ame-010919	Astyanax mexicanus	64.94	0.00e+00	3112.00
IUUC-Bta-013088	Bos taurus	92.89	0.00e+00	5615.00
IUUC-Bdi-014471	Brachypodium distachyon	23.32	4.00e-17	83.60
IUUC-Cja-019137	Callithrix jacchus	96.46	0.00e+00	5847.00
IUUC-Cfa-021215	Canis familiaris	93.11	0.00e+00	5626.00
IUUC-Cpo-022333	Cavia porcellus	86.35	0.00e+00	4982.00
IUUC-Csa-023151	Chlorocebus sabaeus	98.23	0.00e+00	5947.00
IUUC-Cho-024613	Choloepus hoffmanni	84.07	0.00e+00	1931.00
IUUC-Csv-026055	Ciona savignyi	30.58	0.00e+00	858.00
IUUC-Dno-029601	Dasypus novemcinctus	88.55	0.00e+00	5261.00
IUUC-Dor-030381	Dipodomys ordii	89.26	0.00e+00	1607.00
IUUC-Ete-032464	Echinops telfairi	84.01	0.00e+00	2689.00
IUUC-Eeu-035011	Erinaceus europaeus	84.22	0.00e+00	2589.00
IUUC-Fca-035735	Felis catus	92.95	0.00e+00	5598.00
IUUC-Fal-037367	Ficedula albicollis	76.93	0.00e+00	4466.00
IUUC-Gmo-038687	Gadus morhua	60.02	0.00e+00	2472.00
IUUC-Gac-041986	Gasterosteus aculeatus	60.84	0.00e+00	3435.00
IUUC-Ggo-044811	Gorilla gorilla	98.69	0.00e+00	6004.00
IUUC-Lch-050020	Latimeria chalumnae	71.85	0.00e+00	4123.00
IUUC-Lpe-051382	Leersia perrieri	32.58	2.00e-42	169.00
IUUC-Loc-052909	Lepisosteus oculatus	70.25	0.00e+00	4073.00
IUUC-Laf-054195	Loxodonta africana	92.10	0.00e+00	5585.00
IUUC-Mcc-055646	Macaca mulatta	98.29	0.00e+00	5954.00
IUUC-Meu-056627	Macropus eugenii	78.12	0.00e+00	1504.00
IUUC-Mtr-058725	Medicago truncatula	35.98	4.00e-38	155.00
IUUC-Mga-060009	Meleagris gallopavo	68.73	0.00e+00	3224.00
IUUC-Mmr-060784	Microcebus murinus	93.21	0.00e+00	5558.00
IUUC-Mdo-062914	Monodelphis domestica	84.01	0.00e+00	5106.00
IUUC-Mmu-063808	Mus musculus	88.19	0.00e+00	5255.00
IUUC-Mlu-067458	Myotis lucifugus	88.93	0.00e+00	5348.00
IUUC-Nle-070123	Nomascus leucogenys	97.64	0.00e+00	5922.00
IUUC-Ont-071658	Oreochromis niloticus	61.63	0.00e+00	3536.00
IUUC-Ocu-074048	Oryctolagus cuniculus	89.65	0.00e+00	5393.00
IUUC-Oba-075826	Oryza barthii	28.09	9.00e-44	174.00
IUUC-Obr-076145	Oryza brachyantha	29.12	2.00e-40	162.00
IUUC-Ogu-078307	Oryza glumaepatula	27.75	2.00e-42	169.00
IUUC-Oin-080118	Oryza indica	27.92	1.00e-42	169.00
IUUC-Olo-080848	Oryza longistaminata	27.92	7.00e-43	170.00
IUUC-Oni-082792	Oryza nivara	27.25	2.00e-43	172.00
IUUC-Opu-084153	Oryza punctata	28.06	3.00e-42	168.00
IUUC-Oru-084415	Oryza rufipogon	26.94	7.00e-43	170.00
IUUC-Osa-085332	Oryza sativa	23.64	2.00e-20	94.40
IUUC-Ola-086945	Oryzias latipes	59.72	0.00e+00	3388.00
IUUC-Oga-088816	Otolemur garnettii	92.66	0.00e+00	5601.00
IUUC-Oar-089618	Ovis aries	92.92	0.00e+00	5595.00
IUUC-Ptr-090937	Pan troglodytes	99.38	0.00e+00	6040.00
IUUC-Pan-092151	Papio anubis	98.36	0.00e+00	5995.00
IUUC-Psi-093590	Pelodiscus sinensis	78.56	0.00e+00	4669.00
IUUC-Pfo-097445	Poecilia formosa	59.76	0.00e+00	3379.00
IUUC-Pab-098237	Pongo abelii	97.87	0.00e+00	5937.00
IUUC-Pop-098812	Populus trichocarpa	33.33	2.00e-29	125.00
IUUC-Pca-101008	Procavia capensis	86.39	0.00e+00	1632.00
IUUC-Ppe-101610	Prunus persica	29.55	8.00e-36	147.00
IUUC-Pva-102348	Pteropus vampyrus	87.16	0.00e+00	3421.00
IUUC-Rno-105076	Rattus norvegicus	89.64	0.00e+00	5331.00
IUUC-Sha-106860	Sarcophilus harrisii	84.80	0.00e+00	5163.00
IUUC-Sja-107657	Schizosaccharomyces japonicus	27.68	4.00e-25	110.00
IUUC-Sar-113751	Sorex araneus	88.98	0.00e+00	2517.00
IUUC-Ssc-116371	Sus scrofa	92.43	0.00e+00	5611.00
IUUC-Tgu-117108	Taeniopygia guttata	76.50	0.00e+00	4524.00
IUUC-Tru-117628	Takifugu rubripes	60.19	0.00e+00	3404.00
IUUC-Tsy-118837	Tarsius syrichta	87.40	0.00e+00	3468.00
IUUC-Tca-121789	Theobroma cacao	27.10	7.00e-32	134.00
IUUC-Tae-125726	Triticum aestivum	29.01	3.00e-33	139.00
IUUC-Tbe-127953	Tupaia belangeri	90.74	0.00e+00	2989.00
IUUC-Ttr-128991	Tursiops truncatus	91.69	0.00e+00	4751.00
IUUC-Vpa-130309	Vicugna pacos	91.09	0.00e+00	3124.00
IUUC-Xtr-132582	Xenopus tropicalis	71.01	0.00e+00	4275.00
IUUC-Xma-134109	Xiphophorus maculatus	60.36	0.00e+00	3444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence