iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Cullin	37.13	3.00e-94	344.00	IUUC-Hsa-045663
E3 adaptor/Cullin RING/APC_C/APC_C	37.13	3.00e-94	344.00	IUUC-Hsa-045663
E3 adaptor/Cullin RING/APC_C/APC_C	22.78	9.00e-26	114.00	IUUC-Sce-106292

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication.

Protein Sequence
(Fasta)

MEALGSSDCN LEILETLSDD AIQEITESYD GFFTTVESLI AGTGDSLVED EFVSHVYCLC 60
KYGLDSLVRD HFLRSLEQAF EKGGASSFWQ HFDAYSEKKH HNYGEEIQIV LCKALEEISI 120

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Nucleotide Sequence
(Fasta)

CTAATAAAAC GTCTTTTTTA ATTCCGTTTT GTTTTTGCGT TTGTTAGCGT TTTATAATTG 60
CGTTTGTGAA TGACCAAACT TTATGAATCT TCTTCTATAG CTTCTCTCTC TGAACTTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR014786--APC_su2_C
IPR011989--ARM-like
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF08672--ANAPC2
PF00888--Cullin

SMART

SM01013--APC2
SM00182--CULLIN

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005634--C:nucleus
GO:0005819--C:spindle
GO:0031625--F:ubiquitin protein ligase binding
GO:0051301--P:cell division
GO:0009561--P:megagametogenesis
GO:0007067--P:mitotic nuclear division
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT2G04660

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000110	Aegilops tauschii	62.03	0.00e+00	978.00
IUUC-Aml-001248	Ailuropoda melanoleuca	30.17	9.00e-96	343.00
IUUC-Atr-002679	Amborella trichopoda	62.36	0.00e+00	1026.00
IUUC-Apl-003362	Anas platyrhynchos	35.88	9.00e-96	343.00
IUUC-Aca-004655	Anolis carolinensis	38.26	5.00e-100	358.00
IUUC-Aly-006274	Arabidopsis lyrata	96.54	0.00e+00	1634.00
IUUC-Ago-007945	Ashbya gossypii	22.22	8.00e-12	65.10
IUUC-Acl-008276	Aspergillus clavatus	31.95	1.00e-65	243.00
IUUC-Afl-008425	Aspergillus flavus	33.71	9.00e-64	237.00
IUUC-Afu-008876	Aspergillus fumigatus	31.09	1.00e-65	244.00
IUUC-Ani-009501	Aspergillus nidulans	32.25	4.00e-66	245.00
IUUC-Ang-009519	Aspergillus niger	32.96	5.00e-66	245.00
IUUC-Aor-009911	Aspergillus oryzae	34.03	9.00e-64	237.00
IUUC-Ate-010350	Aspergillus terreus	35.02	6.00e-56	212.00
IUUC-Ame-011184	Astyanax mexicanus	33.91	2.00e-88	320.00
IUUC-Bgr-011977	Blumeria graminis	30.76	1.00e-58	220.00
IUUC-Bta-013406	Bos taurus	36.47	3.00e-63	235.00
IUUC-Bci-013817	Botrytis cinerea	30.88	4.00e-56	212.00
IUUC-Bdi-014198	Brachypodium distachyon	62.40	0.00e+00	981.00
IUUC-Bol-015766	Brassica oleracea	86.72	0.00e+00	1438.00
IUUC-Bra-017977	Brassica rapa	87.20	0.00e+00	1444.00
IUUC-Cel-018129	Caenorhabditis elegans	27.16	5.00e-48	185.00
IUUC-Cja-019940	Callithrix jacchus	35.31	9.00e-98	350.00
IUUC-Cfa-020113	Canis familiaris	37.98	7.00e-94	338.00
IUUC-Cpo-021669	Cavia porcellus	34.52	1.00e-95	343.00
IUUC-Cre-022990	Chlamydomonas reinhardtii	53.12	2.00e-38	153.00
IUUC-Csa-023060	Chlorocebus sabaeus	37.50	2.00e-96	346.00
IUUC-Cin-025736	Ciona intestinalis	34.09	1.00e-78	286.00
IUUC-Csv-026175	Ciona savignyi	28.73	3.00e-17	80.50
IUUC-Cgl-026442	Colletotrichum gloeosporioides	30.15	2.00e-53	203.00
IUUC-Cne-026902	Cryptococcus neoformans	33.67	4.00e-63	235.00
IUUC-Cme-027318	Cyanidioschyzon merolae	24.69	2.00e-26	114.00
IUUC-Dre-028318	Danio rerio	36.27	3.00e-101	362.00
IUUC-Dno-029026	Dasypus novemcinctus	32.15	3.00e-83	303.00
IUUC-Dor-031148	Dipodomys ordii	36.51	2.00e-83	303.00
IUUC-Dse-031458	Dothistroma septosporum	23.94	3.00e-27	116.00
IUUC-Dme-032025	Drosophila melanogaster	38.36	2.00e-93	336.00
IUUC-Ete-033154	Echinops telfairi	34.85	3.00e-57	216.00
IUUC-Eca-033812	Equus caballus	35.88	7.00e-79	287.00
IUUC-Eeu-035246	Erinaceus europaeus	32.84	8.00e-29	121.00
IUUC-Fca-035890	Felis catus	37.20	8.00e-92	330.00
IUUC-Fal-037639	Ficedula albicollis	36.32	1.00e-95	343.00
IUUC-Fox-037792	Fusarium oxysporum	30.34	5.00e-57	215.00
IUUC-Fso-038191	Fusarium solani	29.55	2.00e-53	203.00
IUUC-Gmo-039138	Gadus morhua	36.91	1.00e-90	327.00
IUUC-Ggr-040106	Gaeumannomyces graminis	28.03	6.00e-43	169.00
IUUC-Gga-040327	Gallus gallus	33.70	6.00e-96	344.00
IUUC-Gac-042053	Gasterosteus aculeatus	38.51	6.00e-78	285.00
IUUC-Gma-043658	Glycine max	69.90	0.00e+00	1194.00
IUUC-Ggo-045094	Gorilla gorilla	37.32	2.00e-96	346.00
IUUC-Hsa-045663	Homo sapiens	37.32	3.00e-96	345.00
IUUC-Hvu-047677	Hordeum vulgare	61.52	0.00e+00	850.00
IUUC-Itr-047927	Ictidomys tridecemlineatus	34.73	2.00e-95	343.00
IUUC-Kpa-049177	Komagataella pastoris	30.87	2.00e-59	223.00
IUUC-Lch-049435	Latimeria chalumnae	39.73	1.00e-100	360.00
IUUC-Lpe-050728	Leersia perrieri	61.58	0.00e+00	941.00
IUUC-Loc-052561	Lepisosteus oculatus	38.33	4.00e-91	328.00
IUUC-Lma-052995	Leptosphaeria maculans	27.64	2.00e-48	187.00
IUUC-Laf-053447	Loxodonta africana	34.24	3.00e-95	342.00
IUUC-Mcc-054960	Macaca mulatta	37.50	2.00e-96	346.00
IUUC-Meu-056836	Macropus eugenii	39.25	4.00e-89	322.00
IUUC-Mor-057155	Magnaporthe oryzae	27.32	4.00e-32	133.00
IUUC-Mpo-057560	Magnaporthe poae	28.45	1.00e-32	134.00
IUUC-Mtr-058784	Medicago truncatula	69.55	0.00e+00	1214.00
IUUC-Mla-058965	Melampsora laricipopulina	34.94	2.00e-56	212.00
IUUC-Mga-059511	Meleagris gallopavo	33.21	3.00e-94	338.00
IUUC-Mvi-060393	Microbotryum violaceum	33.01	5.00e-68	251.00
IUUC-Mmr-061594	Microcebus murinus	34.89	2.00e-96	345.00
IUUC-Mdo-063009	Monodelphis domestica	39.44	6.00e-90	324.00
IUUC-Mmu-063535	Mus musculus	35.04	7.00e-89	321.00
IUUC-Mac-065167	Musa acuminata	65.38	0.00e+00	1096.00
IUUC-Mpu-065758	Mustela putorius furo	35.05	3.00e-97	349.00
IUUC-Nfi-068614	Neosartorya fischeri	30.41	9.00e-65	241.00
IUUC-Ncr-068900	Neurospora crassa	25.00	2.00e-29	124.00
IUUC-Nle-069236	Nomascus leucogenys	32.32	2.00e-76	280.00
IUUC-Opr-070724	Ochotona princeps	36.38	1.00e-77	283.00
IUUC-Ont-072662	Oreochromis niloticus	36.11	4.00e-78	285.00
IUUC-Oan-073106	Ornithorhynchus anatinus	32.27	2.00e-24	106.00
IUUC-Oba-075268	Oryza barthii	61.35	0.00e+00	945.00
IUUC-Obr-076594	Oryza brachyantha	64.58	0.00e+00	995.00
IUUC-Ogl-077092	Oryza glaberrima	63.50	0.00e+00	1002.00
IUUC-Ogu-078791	Oryza glumaepatula	61.21	0.00e+00	926.00
IUUC-Oin-079065	Oryza indica	63.53	0.00e+00	999.00
IUUC-Olo-080300	Oryza longistaminata	62.98	0.00e+00	909.00
IUUC-Ome-081502	Oryza meridionalis	61.35	0.00e+00	942.00
IUUC-Oni-082212	Oryza nivara	61.35	0.00e+00	945.00
IUUC-Opu-083508	Oryza punctata	60.69	0.00e+00	944.00
IUUC-Oru-084815	Oryza rufipogon	61.05	0.00e+00	923.00
IUUC-Osa-085494	Oryza sativa	63.53	0.00e+00	999.00
IUUC-Ola-087495	Oryzias latipes	34.86	7.00e-88	317.00
IUUC-Olu-087578	Ostreococcus lucimarinus	41.01	2.00e-70	259.00
IUUC-Oga-088026	Otolemur garnettii	34.24	4.00e-100	358.00
IUUC-Oar-089448	Ovis aries	28.04	3.00e-35	142.00
IUUC-Ptr-090626	Pan troglodytes	30.97	4.00e-75	275.00
IUUC-Pan-092841	Papio anubis	37.50	2.00e-96	346.00
IUUC-Psi-093519	Pelodiscus sinensis	35.59	2.00e-53	202.00
IUUC-Pno-094923	Phaeosphaeria nodorum	23.34	9.00e-19	88.20
IUUC-Ppa-095741	Physcomitrella patens	52.05	0.00e+00	642.00
IUUC-Pfo-096798	Poecilia formosa	34.53	5.00e-95	342.00
IUUC-Pab-097600	Pongo abelii	34.73	8.00e-97	347.00
IUUC-Pop-099171	Populus trichocarpa	71.53	0.00e+00	1178.00
IUUC-Pca-101085	Procavia capensis	28.32	3.00e-81	295.00
IUUC-Ppe-101600	Prunus persica	71.93	0.00e+00	1210.00
IUUC-Pva-102210	Pteropus vampyrus	34.84	7.00e-97	347.00
IUUC-Pgr-103279	Puccinia graminis	35.08	6.00e-62	231.00
IUUC-Ptt-103707	Puccinia triticina	33.33	1.00e-50	194.00
IUUC-Pte-104344	Pyrenophora teres	26.24	2.00e-48	187.00
IUUC-Pyt-104781	Pyrenophora triticirepentis	32.40	9.00e-32	131.00
IUUC-Rno-104923	Rattus norvegicus	35.33	3.00e-59	223.00
IUUC-Sce-106292	Saccharomyces cerevisiae	29.60	2.00e-17	83.60
IUUC-Sha-107256	Sarcophilus harrisii	39.44	2.00e-89	323.00
IUUC-Sja-107869	Schizosaccharomyces japonicus	28.99	7.00e-67	248.00
IUUC-Spo-108218	Schizosaccharomyces pombe	33.71	3.00e-63	236.00
IUUC-Smo-108710	Selaginella moellendorffii	47.16	1.00e-173	602.00
IUUC-Sit-110252	Setaria italica	63.66	0.00e+00	964.00
IUUC-Sly-111678	Solanum lycopersicum	68.68	0.00e+00	1113.00
IUUC-Stu-112740	Solanum tuberosum	69.02	0.00e+00	1151.00
IUUC-Sbi-114620	Sorghum bicolor	61.78	0.00e+00	857.00
IUUC-Sre-115165	Sporisorium reilianum	29.15	2.00e-16	80.90
IUUC-Tgu-116996	Taeniopygia guttata	32.39	2.00e-97	349.00
IUUC-Tru-118128	Takifugu rubripes	36.01	3.00e-90	325.00
IUUC-Tni-120443	Tetraodon nigroviridis	38.37	7.00e-89	321.00
IUUC-Tca-121062	Theobroma cacao	71.91	0.00e+00	1217.00
IUUC-Tre-121916	Trichoderma reesei	30.02	4.00e-57	215.00
IUUC-Tvi-122395	Trichoderma virens	30.37	2.00e-55	210.00
IUUC-Tae-124638	Triticum aestivum	61.92	0.00e+00	987.00
IUUC-Tme-126929	Tuber melanosporum	32.56	4.00e-62	231.00
IUUC-Ttr-128180	Tursiops truncatus	38.05	6.00e-98	351.00
IUUC-Uma-129453	Ustilago maydis	26.37	1.00e-16	80.90
IUUC-Vda-129887	Verticillium dahliae	32.70	3.00e-25	109.00
IUUC-Vvi-130919	Vitis vinifera	70.85	0.00e+00	1196.00
IUUC-Xtr-132418	Xenopus tropicalis	33.07	5.00e-106	378.00
IUUC-Xma-133612	Xiphophorus maculatus	36.18	4.00e-95	341.00
IUUC-Yli-134637	Yarrowia lipolytica	30.82	2.00e-56	213.00
IUUC-Zma-135885	Zea mays	60.84	0.00e+00	922.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence