iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013054

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02008545

Gene Name

UBE2U

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000040268.2	ENSBTAT00000054674.2	ENSBTAP00000052146.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.40e-37	126.8	9	141

Active Site

Position(s)	Description	Evidence
89	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkee 89
           lk+e++el++++ egi+a p +e d+++w+v i+G ++t+++g vF+l+i+f+ +Y+f PP vkf t  fhPnv+++ Gk C+++l+++
   Q: 9    LKREFQELKNNNYEGITAFPISE-DMMQWDVDIEGLQNTIWHGAVFQLRINFTAEYNFVPPVVKFRTIPFHPNVDPHsGKPCIDFLDSP 96
           789********************.9****************************************************9*********** PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeyk 134
           +kW+  ++++s+ll++q +l++p  e+p+n eaa++l k+++ y+
   Q: 97   HKWNRSYTLSSILLTLQVMLSNPVLENPVNLEAAHILMKDETLYR 141
           ****************************************99997 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MYSRAYILLK REFQELKNNN YEGITAFPIS EDMMQWDVDI EGLQNTIWHG AVFQLRINFT 60
AEYNFVPPVV KFRTIPFHPN VDPHSGKPCI DFLDSPHKWN RSYTLSSILL TLQVMLSNPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTTGCATC TTCTTGCCCA ACCCGCACAC AGTTACACCT GTGAAGCGGA GACGGTGACT 60
GGTTAAGCAC ACCCTAAACT TAACGCCTCT TACGCCCACT TCATGCACAA GCAGCACGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002211	Ailuropoda melanoleuca	63.41	6.00e-70	256.00
IUUC-Aca-004682	Anolis carolinensis	40.00	1.00e-49	189.00
IUUC-Cja-018784	Callithrix jacchus	52.71	2.00e-93	335.00
IUUC-Cfa-020877	Canis familiaris	67.10	3.00e-90	324.00
IUUC-Cpo-022462	Cavia porcellus	58.43	3.00e-58	217.00
IUUC-Csa-023486	Chlorocebus sabaeus	72.12	7.00e-97	346.00
IUUC-Cho-024685	Choloepus hoffmanni	44.83	3.00e-54	205.00
IUUC-Dno-029061	Dasypus novemcinctus	59.18	8.00e-102	363.00
IUUC-Ete-032233	Echinops telfairi	49.11	5.00e-59	220.00
IUUC-Eca-033400	Equus caballus	72.90	2.00e-54	204.00
IUUC-Fca-035778	Felis catus	58.49	1.00e-107	382.00
IUUC-Ggo-044718	Gorilla gorilla	59.26	4.00e-105	374.00
IUUC-Hsa-046798	Homo sapiens	58.95	1.00e-103	369.00
IUUC-Lch-050337	Latimeria chalumnae	38.04	7.00e-63	233.00
IUUC-Loc-051819	Lepisosteus oculatus	37.15	9.00e-54	203.00
IUUC-Laf-054536	Loxodonta africana	65.64	2.00e-90	325.00
IUUC-Mcc-055028	Macaca mulatta	58.13	2.00e-104	372.00
IUUC-Mmr-061623	Microcebus murinus	55.38	6.00e-90	323.00
IUUC-Mdo-062614	Monodelphis domestica	38.37	2.00e-56	213.00
IUUC-Mmu-063194	Mus musculus	49.22	5.00e-68	251.00
IUUC-Mpu-066467	Mustela putorius furo	61.44	8.00e-105	373.00
IUUC-Mlu-067976	Myotis lucifugus	61.06	2.00e-72	265.00
IUUC-Nle-069407	Nomascus leucogenys	58.33	2.00e-100	358.00
IUUC-Opr-070526	Ochotona princeps	61.14	3.00e-52	198.00
IUUC-Oan-073005	Ornithorhynchus anatinus	47.49	5.00e-49	187.00
IUUC-Ocu-074953	Oryctolagus cuniculus	55.86	2.00e-91	328.00
IUUC-Oga-089061	Otolemur garnettii	59.69	9.00e-106	376.00
IUUC-Oar-090147	Ovis aries	84.49	1.00e-149	522.00
IUUC-Ptr-090873	Pan troglodytes	59.49	4.00e-103	367.00
IUUC-Pan-091873	Papio anubis	71.24	2.00e-95	341.00
IUUC-Psi-093780	Pelodiscus sinensis	39.00	3.00e-37	148.00
IUUC-Pab-098662	Pongo abelii	74.34	8.00e-100	355.00
IUUC-Pca-100167	Procavia capensis	46.02	7.00e-55	207.00
IUUC-Pva-102119	Pteropus vampyrus	47.49	2.00e-41	162.00
IUUC-Rno-105522	Rattus norvegicus	40.89	1.00e-67	250.00
IUUC-Sar-113070	Sorex araneus	51.96	8.00e-55	206.00
IUUC-Ssc-115890	Sus scrofa	70.75	4.00e-128	450.00
IUUC-Tsy-119341	Tarsius syrichta	64.71	2.00e-74	271.00
IUUC-Tbe-127433	Tupaia belangeri	45.20	3.00e-60	225.00
IUUC-Ttr-128614	Tursiops truncatus	64.91	2.00e-105	375.00
IUUC-Vpa-130777	Vicugna pacos	63.35	7.00e-110	390.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence