iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013081

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Polycomb group RING finger protein 5

Genbank Nucleotide ID

BC126565

Gene Name

PCGF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004964.5	ENSBTAT00000006533.5	ENSBTAP00000006533.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/RAWUL	2.40e-32	111.4	138	249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk...lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwk.......... 76
           i+++L++l++n++++d++   l+kk++rcs+r+tV+++kkfl++klkl+ssye+d+lc++e++++++t+e+i y+++w+          
   Q: 138  IAICLDCLRNNGQSGDNVvkgLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFI-YMTRWRlrgenfrcln 225
           79**********************************************************************.**************** PP
   S: 77   ..............kegpLvLqYr 86
                         +++p+vLqYr
   Q: 226  csasqvcsqdgplyQSYPMVLQYR 249
           ***********************9 PP

Organism

Bos taurus

Functional Description
(View)

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

Protein Sequence
(Fasta)

MATQRKHLVK DFNPYITCYI CKGYLIKPTT VTECLHTFCK TCIVQHFEDS NDCPRCGNQV 60
HETNPLEMLR LDNTLEEIIF KLVPGLREQL ERESEFWKKN KPQENGQDDM SKVDKPKVDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAGATA TGGGAAAGCA GAACCACCAA AAGGAGTGAT GACCAGCGAT CTCATGAGAA 60
GTCTGGATGT TAGTTCTCAT GCCTCGGGAT ACCCAGTTGG GAACTCCACA CCAGCTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005730--C:nucleolus
GO:0031519--C:PcG protein complex
GO:0008270--F:zinc ion binding
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

KEGG

bta:528946

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002093	Ailuropoda melanoleuca	98.07	4.00e-140	489.00
IUUC-Apl-003757	Anas platyrhynchos	94.14	5.00e-120	423.00
IUUC-Aca-005032	Anolis carolinensis	88.28	7.00e-110	389.00
IUUC-Ame-011418	Astyanax mexicanus	68.73	3.00e-93	333.00
IUUC-Cja-019296	Callithrix jacchus	97.66	1.00e-137	481.00
IUUC-Cfa-020437	Canis familiaris	98.44	3.00e-140	490.00
IUUC-Cpo-022107	Cavia porcellus	98.06	5.00e-140	489.00
IUUC-Csa-023103	Chlorocebus sabaeus	98.44	6.00e-133	466.00
IUUC-Cho-025053	Choloepus hoffmanni	100.00	8.00e-38	150.00
IUUC-Dre-028409	Danio rerio	71.88	1.00e-98	352.00
IUUC-Dno-030077	Dasypus novemcinctus	98.83	7.00e-141	492.00
IUUC-Dor-030893	Dipodomys ordii	98.17	6.00e-117	412.00
IUUC-Ete-033131	Echinops telfairi	79.69	3.00e-105	374.00
IUUC-Eca-034226	Equus caballus	95.70	4.00e-136	476.00
IUUC-Eeu-034466	Erinaceus europaeus	81.64	8.00e-109	385.00
IUUC-Fca-035545	Felis catus	99.22	9.00e-142	495.00
IUUC-Fal-037615	Ficedula albicollis	94.14	5.00e-120	423.00
IUUC-Gmo-038871	Gadus morhua	65.75	8.00e-80	289.00
IUUC-Gga-040926	Gallus gallus	92.97	1.00e-125	441.00
IUUC-Gac-042006	Gasterosteus aculeatus	76.08	3.00e-98	350.00
IUUC-Ggo-045087	Gorilla gorilla	98.44	6.00e-133	466.00
IUUC-Hsa-046738	Homo sapiens	98.44	6.00e-133	466.00
IUUC-Itr-048443	Ictidomys tridecemlineatus	98.41	6.00e-99	352.00
IUUC-Lch-050434	Latimeria chalumnae	82.81	2.00e-111	394.00
IUUC-Loc-052649	Lepisosteus oculatus	78.21	9.00e-108	382.00
IUUC-Laf-053509	Loxodonta africana	98.83	6.00e-141	492.00
IUUC-Mcc-055709	Macaca mulatta	98.44	4.00e-133	466.00
IUUC-Meu-056663	Macropus eugenii	80.86	1.00e-108	385.00
IUUC-Mga-059573	Meleagris gallopavo	92.91	3.00e-124	437.00
IUUC-Mmr-060776	Microcebus murinus	99.22	2.00e-142	498.00
IUUC-Mdo-061959	Monodelphis domestica	96.88	1.00e-137	481.00
IUUC-Mmu-063483	Mus musculus	88.28	6.00e-118	416.00
IUUC-Mpu-066861	Mustela putorius furo	99.22	9.00e-142	495.00
IUUC-Mlu-067880	Myotis lucifugus	98.83	6.00e-141	492.00
IUUC-Nle-069264	Nomascus leucogenys	98.44	6.00e-133	466.00
IUUC-Opr-070746	Ochotona princeps	71.09	2.00e-89	322.00
IUUC-Ont-071361	Oreochromis niloticus	75.19	2.00e-101	361.00
IUUC-Oan-073482	Ornithorhynchus anatinus	79.07	4.00e-109	387.00
IUUC-Ocu-073885	Oryctolagus cuniculus	98.44	1.00e-140	491.00
IUUC-Ola-086999	Oryzias latipes	76.47	9.00e-105	372.00
IUUC-Oga-088504	Otolemur garnettii	98.05	2.00e-140	491.00
IUUC-Oar-089963	Ovis aries	98.44	8.00e-141	492.00
IUUC-Ptr-090820	Pan troglodytes	97.66	3.00e-132	464.00
IUUC-Pan-092600	Papio anubis	98.44	4.00e-133	466.00
IUUC-Psi-093699	Pelodiscus sinensis	94.14	2.00e-127	447.00
IUUC-Pma-094238	Petromyzon marinus	63.81	1.00e-88	318.00
IUUC-Pfo-096402	Poecilia formosa	71.71	1.00e-93	335.00
IUUC-Pab-097621	Pongo abelii	98.44	6.00e-133	466.00
IUUC-Pca-100342	Procavia capensis	97.66	7.00e-132	462.00
IUUC-Pva-103118	Pteropus vampyrus	99.22	4.00e-134	470.00
IUUC-Rno-105427	Rattus norvegicus	94.22	1.00e-112	399.00
IUUC-Sha-107627	Sarcophilus harrisii	95.24	8.00e-95	338.00
IUUC-Sit-109956	Setaria italica	36.04	3.00e-11	63.50
IUUC-Sar-113005	Sorex araneus	85.94	7.00e-127	446.00
IUUC-Ssc-116448	Sus scrofa	82.76	5.00e-82	296.00
IUUC-Tgu-117081	Taeniopygia guttata	94.14	5.00e-120	423.00
IUUC-Tru-117696	Takifugu rubripes	71.05	1.00e-94	339.00
IUUC-Tsy-119052	Tarsius syrichta	83.49	8.00e-103	365.00
IUUC-Tni-120530	Tetraodon nigroviridis	72.31	2.00e-95	341.00
IUUC-Tbe-127914	Tupaia belangeri	79.30	7.00e-105	372.00
IUUC-Ttr-128739	Tursiops truncatus	83.98	4.00e-112	397.00
IUUC-Vpa-130189	Vicugna pacos	97.66	9.00e-138	482.00
IUUC-Xtr-131995	Xenopus tropicalis	78.99	1.00e-100	358.00
IUUC-Xma-133038	Xiphophorus maculatus	76.68	3.00e-87	314.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence