iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000183091.19	ENST00000409198.5	ENSP00000386259.1
ENSG00000183091.19	ENST00000397337.6	ENSP00000380498.2
ENSG00000183091.19	ENST00000413693.5	ENSP00000410961.1
ENSG00000183091.19	ENST00000434685.5	ENSP00000389074.1
ENSG00000183091.19	ENST00000604864.5	ENSP00000474498.1
ENSG00000183091.19	ENST00000603639.5	ENSP00000473894.1
ENSG00000183091.19	ENST00000421461.6	ENSP00000408570.2
ENSG00000183091.19	ENST00000424585.1	ENSP00000404876.1
ENSG00000183091.19	ENST00000618972.4	ENSP00000484342.1
ENSG00000183091.19	ENST00000172853.14	ENSP00000172853.10

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
AREsite	circBase	circRNADb	CircNet
microRNA	TRANSFAC	RepTar	miRcode
RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
ClinVar	GWASdb	GWAS Central	OMIM
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA	BioGRID
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-12	49.5	8504	8559

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + ++++ydy+a++ de ++k Gd +  +  +  degW++g+ + +g+ G++P+n+ve 
   Q: 8504 KIFRAMYDYMAADADEVSFKDGDAIINV--QAIDEGWMYGTVQRTGRTGMLPANYVEA 8559
           5789********************9999..99************************97 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MADDEDYEEV VEYYTEEVVY EEVPGETITK IYETTTTRTS DYEQSETSKP ALAQPALAQP 60
ASAKPVERRK VIRKKVDPSK FMTPYIAHSQ KMQDLFSPNK YKEKFEKTKG QPYASTTDTP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCATCACG CTGGCTTTTG CCTGGGGTTC TCAGGAGGGG AGAGTTGGGA GAGGCTTTGC 60
TGCTGAGGAA ATTTATTTGG TAGATTGAAG GTAAGGCCAG TTTATGACTT TTTCTGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR013998--Nebulin
IPR000900--Nebulin_repeat
IPR000994--Pept_M24
IPR001452--SH3_domain

PROSITE

PS51216--NEBULIN
PS50002--SH3

Pfam

PF00880--Nebulin
PF14604--SH3_9

PRINTS

PR00510--NEBULIN

SMART

SM00227--NEBU
SM00326--SH3

Gene Ontology

GO:0030018--C:Z disc

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001370	Ailuropoda melanoleuca	68.19	0.00e+00	8982.00
IUUC-Apl-004014	Anas platyrhynchos	74.25	0.00e+00	3539.00
IUUC-Aca-004960	Anolis carolinensis	58.59	0.00e+00	7692.00
IUUC-Ame-011885	Astyanax mexicanus	54.63	0.00e+00	2202.00
IUUC-Bta-012532	Bos taurus	67.64	0.00e+00	8916.00
IUUC-Cja-018875	Callithrix jacchus	67.23	0.00e+00	8472.00
IUUC-Cpo-021399	Cavia porcellus	67.39	0.00e+00	8425.00
IUUC-Cho-024491	Choloepus hoffmanni	80.98	0.00e+00	3244.00
IUUC-Cin-025315	Ciona intestinalis	36.36	2.00e-48	186.00
IUUC-Csv-026276	Ciona savignyi	29.24	3.00e-99	356.00
IUUC-Dre-028010	Danio rerio	48.39	0.00e+00	5457.00
IUUC-Dno-029499	Dasypus novemcinctus	73.37	0.00e+00	10710.00
IUUC-Ete-032651	Echinops telfairi	81.81	0.00e+00	4531.00
IUUC-Eca-034257	Equus caballus	66.54	0.00e+00	8660.00
IUUC-Eeu-035018	Erinaceus europaeus	76.39	0.00e+00	4482.00
IUUC-Fca-036353	Felis catus	66.86	0.00e+00	8454.00
IUUC-Fal-037112	Ficedula albicollis	73.58	0.00e+00	1226.00
IUUC-Gmo-038958	Gadus morhua	46.93	0.00e+00	4625.00
IUUC-Gac-041704	Gasterosteus aculeatus	48.27	0.00e+00	4910.00
IUUC-Ggo-044645	Gorilla gorilla	67.94	0.00e+00	8620.00
IUUC-Itr-047916	Ictidomys tridecemlineatus	70.54	0.00e+00	9570.00
IUUC-Lch-049636	Latimeria chalumnae	62.23	0.00e+00	3532.00
IUUC-Loc-052344	Lepisosteus oculatus	58.39	0.00e+00	3351.00
IUUC-Laf-053919	Loxodonta africana	67.39	0.00e+00	8798.00
IUUC-Mcc-055214	Macaca mulatta	74.99	0.00e+00	11150.00
IUUC-Meu-055907	Macropus eugenii	84.19	0.00e+00	2432.00
IUUC-Mga-059258	Meleagris gallopavo	72.49	0.00e+00	4239.00
IUUC-Mmr-060845	Microcebus murinus	69.68	0.00e+00	10340.00
IUUC-Mdo-062617	Monodelphis domestica	65.84	0.00e+00	8126.00
IUUC-Mmu-063671	Mus musculus	69.39	0.00e+00	9450.00
IUUC-Mlu-067356	Myotis lucifugus	66.77	0.00e+00	8796.00
IUUC-Opr-070306	Ochotona princeps	76.71	0.00e+00	4906.00
IUUC-Ont-071939	Oreochromis niloticus	42.97	0.00e+00	3948.00
IUUC-Oan-072792	Ornithorhynchus anatinus	62.98	0.00e+00	7923.00
IUUC-Ocu-074135	Oryctolagus cuniculus	68.60	0.00e+00	9046.00
IUUC-Oga-088918	Otolemur garnettii	68.68	0.00e+00	8986.00
IUUC-Oar-089309	Ovis aries	68.19	0.00e+00	8952.00
IUUC-Ptr-091592	Pan troglodytes	67.97	0.00e+00	8605.00
IUUC-Pan-091871	Papio anubis	66.91	0.00e+00	8433.00
IUUC-Psi-093081	Pelodiscus sinensis	61.25	0.00e+00	7269.00
IUUC-Pma-094426	Petromyzon marinus	39.41	0.00e+00	1422.00
IUUC-Pab-098061	Pongo abelii	94.33	0.00e+00	4955.00
IUUC-Pva-102225	Pteropus vampyrus	70.98	0.00e+00	7801.00
IUUC-Rno-105476	Rattus norvegicus	66.69	0.00e+00	8424.00
IUUC-Sha-107098	Sarcophilus harrisii	65.92	0.00e+00	8655.00
IUUC-Sar-113759	Sorex araneus	92.61	0.00e+00	2222.00
IUUC-Ssc-116232	Sus scrofa	89.72	0.00e+00	4609.00
IUUC-Tru-118369	Takifugu rubripes	52.56	0.00e+00	2950.00
IUUC-Ttr-129076	Tursiops truncatus	68.45	0.00e+00	7742.00
IUUC-Vpa-130364	Vicugna pacos	79.63	0.00e+00	3781.00
IUUC-Xtr-132703	Xenopus tropicalis	58.28	0.00e+00	6221.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence