iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009294

Ensembl Protein ID

CADANIAP00008407

UniProt Accession

C8VP63; C8VP63_EMENI

Genbank Protein ID

CBF85512.1

Protein Name

Ubiquitin conjugating enzyme Ubc8, putative (AFU_orthologue AFUA_6G09160)

Genbank Nucleotide ID

BN001307

Gene Name

ANIA_01761

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00008407	CADANIAT00008407	CADANIAP00008407

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.30e-31	107.5	27	137

Active Site

Position(s)	Description	Evidence
81	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 29   ewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvl.lsiqsllaepnpespln 119
           e+ v + Gpe+tp++gg +k+++e+p++YP+k+P++ f+++ifhPn++e  G+vCl++++  ++Wsp++++ +++ + + +ll+ pnp++pln
   Q: 27   EFYVRFKGPEETPFAGGHWKIHVELPDQYPYKSPSIGFVNRIFHPNIDELsGSVCLDVIN--QTWSPMYDMINIFeVFLPQLLRYPNPSDPLN 117
           688999*******************************************99********9..*************889*************** PP
   S: 120  eeaaellkknreeykkkvre 139
            eaa +l +++++y+ kv+e
   Q: 118  GEAAAMLMREPKSYEAKVKE 137
           *****************985 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MSSPKRRIET DVMYGLPPLR KGLVKQEFYV RFKGPEETPF AGGHWKIHVE LPDQYPYKSP 60
SIGFVNRIFH PNIDELSGSV CLDVINQTWS PMYDMINIFE VFLPQLLRYP NPSDPLNGEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTAATATCC GGTCTTCCTC CTCATATTCG AACGACAAGT CCATCGCAGT TTTGGCTTAC 60
GAATCGTACT TACTTTTTCG TCCTATCGGC CCGCTTGCCA CCCGCCTCTC TTACTTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000745	Aegilops tauschii	63.92	6.00e-56	208.00
IUUC-Aml-001260	Ailuropoda melanoleuca	57.76	3.00e-46	175.00
IUUC-Atr-002681	Amborella trichopoda	62.99	2.00e-55	206.00
IUUC-Apl-003547	Anas platyrhynchos	63.85	4.00e-43	165.00
IUUC-Aca-005224	Anolis carolinensis	63.85	5.00e-44	168.00
IUUC-Aly-005836	Arabidopsis lyrata	62.09	1.00e-54	204.00
IUUC-Ath-007534	Arabidopsis thaliana	61.44	2.00e-54	202.00
IUUC-Ago-007727	Ashbya gossypii	60.67	7.00e-50	188.00
IUUC-Acl-008119	Aspergillus clavatus	84.97	2.00e-82	296.00
IUUC-Afl-008412	Aspergillus flavus	91.45	4.00e-70	254.00
IUUC-Afu-008925	Aspergillus fumigatus	82.18	2.00e-80	289.00
IUUC-Ang-009805	Aspergillus niger	90.22	5.00e-84	301.00
IUUC-Aor-010201	Aspergillus oryzae	86.78	6.00e-75	271.00
IUUC-Ate-010441	Aspergillus terreus	95.21	3.00e-70	254.00
IUUC-Ame-010807	Astyanax mexicanus	56.07	8.00e-31	124.00
IUUC-Bta-012802	Bos taurus	57.76	3.00e-46	175.00
IUUC-Bdi-014415	Brachypodium distachyon	63.92	2.00e-56	209.00
IUUC-Bol-016385	Brassica oleracea	63.09	9.00e-55	204.00
IUUC-Bra-016989	Brassica rapa	63.09	2.00e-54	203.00
IUUC-Cel-018412	Caenorhabditis elegans	54.17	4.00e-46	176.00
IUUC-Cja-019571	Callithrix jacchus	45.93	5.00e-32	128.00
IUUC-Cfa-020811	Canis familiaris	57.76	3.00e-46	175.00
IUUC-Cpo-021889	Cavia porcellus	63.85	2.00e-44	169.00
IUUC-Cre-022956	Chlamydomonas reinhardtii	57.22	5.00e-55	205.00
IUUC-Csa-023289	Chlorocebus sabaeus	57.76	3.00e-46	175.00
IUUC-Cho-024517	Choloepus hoffmanni	62.03	5.00e-21	92.00
IUUC-Cin-025571	Ciona intestinalis	42.77	4.00e-29	118.00
IUUC-Cgl-026627	Colletotrichum gloeosporioides	83.33	1.00e-77	280.00
IUUC-Cne-027006	Cryptococcus neoformans	77.59	5.00e-56	208.00
IUUC-Cme-027171	Cyanidioschyzon merolae	60.93	5.00e-55	205.00
IUUC-Dre-027450	Danio rerio	58.39	7.00e-46	174.00
IUUC-Dno-029838	Dasypus novemcinctus	57.76	3.00e-46	175.00
IUUC-Dor-031119	Dipodomys ordii	57.76	3.00e-46	175.00
IUUC-Dse-031243	Dothistroma septosporum	78.61	9.00e-82	293.00
IUUC-Dme-031807	Drosophila melanogaster	56.60	8.00e-50	187.00
IUUC-Ete-032437	Echinops telfairi	57.58	8.00e-30	121.00
IUUC-Eca-034123	Equus caballus	63.85	2.00e-44	169.00
IUUC-Fca-035502	Felis catus	57.76	3.00e-46	175.00
IUUC-Fal-037054	Ficedula albicollis	63.85	2.00e-44	170.00
IUUC-Fox-037912	Fusarium oxysporum	82.48	9.00e-56	206.00
IUUC-Fso-038148	Fusarium solani	76.24	7.00e-71	257.00
IUUC-Gmo-038858	Gadus morhua	57.76	5.00e-51	191.00
IUUC-Ggr-039749	Gaeumannomyces graminis	79.11	5.00e-73	265.00
IUUC-Gga-040942	Gallus gallus	57.76	3.00e-46	175.00
IUUC-Gac-042079	Gasterosteus aculeatus	57.76	1.00e-51	193.00
IUUC-Gma-044100	Glycine max	63.06	2.00e-57	213.00
IUUC-Hsa-046545	Homo sapiens	57.76	3.00e-46	175.00
IUUC-Hvu-047746	Hordeum vulgare	66.90	3.00e-54	202.00
IUUC-Itr-048474	Ictidomys tridecemlineatus	57.76	3.00e-46	175.00
IUUC-Kpa-049144	Komagataella pastoris	72.87	8.00e-52	194.00
IUUC-Lch-050589	Latimeria chalumnae	57.24	6.00e-44	168.00
IUUC-Lpe-051335	Leersia perrieri	63.92	4.00e-56	208.00
IUUC-Loc-052829	Lepisosteus oculatus	59.09	2.00e-45	173.00
IUUC-Lma-052971	Leptosphaeria maculans	61.28	2.00e-69	253.00
IUUC-Laf-053526	Loxodonta africana	57.76	2.00e-46	176.00
IUUC-Mcc-055611	Macaca mulatta	57.76	3.00e-46	175.00
IUUC-Mor-057278	Magnaporthe oryzae	80.13	2.00e-75	272.00
IUUC-Mpo-057484	Magnaporthe poae	76.32	3.00e-68	248.00
IUUC-Mtr-058579	Medicago truncatula	63.06	3.00e-57	212.00
IUUC-Mla-058926	Melampsora laricipopulina	73.37	3.00e-68	248.00
IUUC-Mga-059801	Meleagris gallopavo	57.76	3.00e-46	175.00
IUUC-Mvi-060244	Microbotryum violaceum	76.97	4.00e-66	241.00
IUUC-Mmr-061205	Microcebus murinus	57.76	3.00e-46	175.00
IUUC-Mdo-062038	Monodelphis domestica	63.74	1.00e-27	112.00
IUUC-Mmu-063974	Mus musculus	57.76	3.00e-46	175.00
IUUC-Mac-065395	Musa acuminata	61.69	9.00e-55	204.00
IUUC-Mpu-066759	Mustela putorius furo	57.76	3.00e-46	175.00
IUUC-Mlu-067674	Myotis lucifugus	63.85	2.00e-44	169.00
IUUC-Nfi-068618	Neosartorya fischeri	96.79	1.00e-77	279.00
IUUC-Ncr-068712	Neurospora crassa	81.53	3.00e-63	231.00
IUUC-Nle-069926	Nomascus leucogenys	57.76	3.00e-46	175.00
IUUC-Opr-070598	Ochotona princeps	57.76	3.00e-46	175.00
IUUC-Ont-071893	Oreochromis niloticus	59.62	1.00e-51	193.00
IUUC-Oan-073273	Ornithorhynchus anatinus	63.85	1.00e-44	170.00
IUUC-Ocu-074357	Oryctolagus cuniculus	61.19	4.00e-45	172.00
IUUC-Oba-075055	Oryza barthii	63.92	4.00e-56	208.00
IUUC-Obr-076538	Oryza brachyantha	63.29	7.00e-56	207.00
IUUC-Ogl-077784	Oryza glaberrima	63.92	4.00e-56	208.00
IUUC-Ogu-078045	Oryza glumaepatula	63.92	4.00e-56	208.00
IUUC-Oin-079163	Oryza indica	63.92	4.00e-56	208.00
IUUC-Olo-080847	Oryza longistaminata	65.35	2.00e-48	183.00
IUUC-Ome-081586	Oryza meridionalis	59.41	5.00e-54	201.00
IUUC-Oni-082913	Oryza nivara	63.92	4.00e-56	208.00
IUUC-Opu-083651	Oryza punctata	63.92	4.00e-56	208.00
IUUC-Oru-084980	Oryza rufipogon	63.92	4.00e-56	208.00
IUUC-Osa-085334	Oryza sativa	65.49	2.00e-53	199.00
IUUC-Ola-087423	Oryzias latipes	58.39	8.00e-52	194.00
IUUC-Oga-088412	Otolemur garnettii	57.76	3.00e-46	175.00
IUUC-Oar-090282	Ovis aries	63.85	2.00e-44	169.00
IUUC-Ptr-090470	Pan troglodytes	57.76	3.00e-46	175.00
IUUC-Pan-092552	Papio anubis	57.76	3.00e-46	175.00
IUUC-Psi-093516	Pelodiscus sinensis	63.85	1.00e-44	170.00
IUUC-Pno-094800	Phaeosphaeria nodorum	80.85	3.00e-62	228.00
IUUC-Ppa-095962	Physcomitrella patens	65.58	5.00e-57	211.00
IUUC-Pfo-097374	Poecilia formosa	58.28	2.00e-46	176.00
IUUC-Pab-098112	Pongo abelii	57.76	3.00e-46	175.00
IUUC-Pop-099367	Populus trichocarpa	63.06	1.00e-56	210.00
IUUC-Pca-100436	Procavia capensis	47.89	1.00e-32	130.00
IUUC-Ppe-101420	Prunus persica	63.06	3.00e-57	212.00
IUUC-Pva-102776	Pteropus vampyrus	58.12	9.00e-47	177.00
IUUC-Pgr-103325	Puccinia graminis	74.84	2.00e-62	229.00
IUUC-Ptt-104010	Puccinia triticina	72.26	1.00e-58	216.00
IUUC-Pte-104024	Pyrenophora teres	70.87	2.00e-74	270.00
IUUC-Pyt-104715	Pyrenophora triticirepentis	82.17	5.00e-71	258.00
IUUC-Rno-105699	Rattus norvegicus	57.14	1.00e-45	174.00
IUUC-Sce-106165	Saccharomyces cerevisiae	63.85	7.00e-45	171.00
IUUC-Sha-106524	Sarcophilus harrisii	63.85	2.00e-44	169.00
IUUC-Sja-107813	Schizosaccharomyces japonicus	68.87	5.00e-59	218.00
IUUC-Spo-108105	Schizosaccharomyces pombe	75.16	2.00e-65	239.00
IUUC-Ssl-108543	Sclerotinia sclerotiorum	68.68	6.00e-63	231.00
IUUC-Smo-108956	Selaginella moellendorffii	58.38	4.00e-58	215.00
IUUC-Sit-110211	Setaria italica	63.92	4.00e-56	209.00
IUUC-Sly-111361	Solanum lycopersicum	61.08	7.00e-62	227.00
IUUC-Stu-112455	Solanum tuberosum	58.38	2.00e-60	223.00
IUUC-Sar-113572	Sorex araneus	44.62	3.00e-22	95.90
IUUC-Sbi-113911	Sorghum bicolor	62.03	3.00e-55	205.00
IUUC-Sre-115027	Sporisorium reilianum	67.37	9.00e-70	253.00
IUUC-Ssc-116221	Sus scrofa	63.08	2.00e-42	162.00
IUUC-Tgu-116965	Taeniopygia guttata	63.85	2.00e-44	169.00
IUUC-Tru-117574	Takifugu rubripes	58.97	5.00e-45	171.00
IUUC-Tni-120422	Tetraodon nigroviridis	58.97	2.00e-45	172.00
IUUC-Tca-121070	Theobroma cacao	64.97	1.00e-57	213.00
IUUC-Tre-122110	Trichoderma reesei	80.25	1.00e-65	240.00
IUUC-Tvi-122592	Trichoderma virens	74.59	2.00e-69	252.00
IUUC-Tae-124343	Triticum aestivum	64.56	3.00e-56	209.00
IUUC-Tur-126414	Triticum urartu	64.56	3.00e-56	209.00
IUUC-Tme-127020	Tuber melanosporum	82.17	1.00e-53	200.00
IUUC-Tbe-128053	Tupaia belangeri	50.00	1.00e-28	117.00
IUUC-Ttr-128734	Tursiops truncatus	57.76	3.00e-46	175.00
IUUC-Uma-129334	Ustilago maydis	68.78	4.00e-70	255.00
IUUC-Vda-129953	Verticillium dahliae	70.26	1.00e-72	263.00
IUUC-Vpa-130729	Vicugna pacos	63.85	2.00e-44	169.00
IUUC-Vvi-131633	Vitis vinifera	63.69	6.00e-57	211.00
IUUC-Xtr-132368	Xenopus tropicalis	57.76	3.00e-46	175.00
IUUC-Xma-133864	Xiphophorus maculatus	58.28	2.00e-46	176.00
IUUC-Yli-134339	Yarrowia lipolytica	74.46	4.00e-68	248.00
IUUC-Zma-135047	Zea mays	65.10	1.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence