iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052039

Ensembl Protein ID

ENSLOCP00000000571.1

UniProt Accession

W5LWR4; W5LWR4_LEPOC

Genbank Protein ID

ENSLOCP00000000571

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01011292

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000000516.1	ENSLOCT00000000572.1	ENSLOCP00000000571.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-22	77.2	1495	1527
UBD/Beta-Prp	1.50e-48	165.7	923	1167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           + c  f  +d+++ +Gs D tikvW++++g+ll
   Q: 1495 ILCAVFseDDRYVFTGSQDRTIKVWETSSGRLL 1527
           6777799766*****************999986 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
             +l g +++vt +++  ++ +l+ gse +   vw+l + + vhtl gh+++v s+++  +g + +s+s+d+t+r+wdl +g+ ++ 
   Q: 923  KTTLTGFQKGVTVMDLCAEKGLLIVGSEEGRMIVWNLLDTEVVHTLFGHTAEVQSVKVLDKGARCLSASRDSTLRLWDLLSGKQIYC 1009
           567889999**********99****************************************************************** PP
   S: 132  tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
           +++g  g+  c++ h ++ + ++ ++  +++  Wdl+t++ll + +g   d+     ++ +g  +vs s+ g +++wd  tg   r+
   Q: 1010 INEGPFGAPVCTQRHVTEqRGVIYSTCGSQMSAWDLETAELLFHIEG--GDAAVFAVLQGKGAAVVSLSDEGVLTFWDSTTGLKQRA 1094
           ***************999899999999******************99..7888888899999******************9999888 PP
   S: 218  lnght...dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse.dskvniw 292
           +   +    + ++v  ++   r+v gs +gs+++     ++  ++ +   ssv+  av   +d + vl+++  + + ++
   Q: 1095 CSLMDdlkLTWTCVLPLRTCGRVVAGSREGSVFLV--SDDERCSVANV-SSSVSFLAV---SDDETVLCAGyAKHIAMF 1167
           87766444556677777899************994..33444444444.444444444...555555544444555555 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MTAASMKETL GLDLLKGHAS GISELRSSVV RVFISSTFSD MSSERDALLE KAYPELQVYC 60
QSLGLVFEVV DMRWGVRDTV VVDHMTTELC LQEIQSCRRV SVGPTFTALV GNRYGYRPIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGGATGAA ACGTTGAAGA AAAGCTTTGC TCCACTAAAC AGCTTGTAAT ACCCCCAGAT 60
GAAACACTTC AAAATGATCT CAGCAGCACT AAACCACTTC TAATAACGTC GCTGCAGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR025139--DUF4062
IPR020472--G-protein_beta_WD-40_rep
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	40.91	0.00e+00	1195.00
IUUC-Apl-003467	Anas platyrhynchos	42.13	3.00e-52	197.00
IUUC-Ame-011400	Astyanax mexicanus	50.34	0.00e+00	1551.00
IUUC-Bta-013223	Bos taurus	41.77	0.00e+00	1039.00
IUUC-Cel-018404	Caenorhabditis elegans	33.95	3.00e-143	503.00
IUUC-Cja-018773	Callithrix jacchus	41.97	0.00e+00	702.00
IUUC-Cfa-020334	Canis familiaris	42.47	0.00e+00	1236.00
IUUC-Cpo-022316	Cavia porcellus	39.24	0.00e+00	1000.00
IUUC-Csa-023631	Chlorocebus sabaeus	40.67	0.00e+00	1176.00
IUUC-Cin-025646	Ciona intestinalis	33.99	3.00e-147	516.00
IUUC-Csv-026191	Ciona savignyi	25.89	3.00e-20	92.80
IUUC-Dre-028241	Danio rerio	48.69	0.00e+00	1483.00
IUUC-Dno-029990	Dasypus novemcinctus	38.84	2.00e-83	302.00
IUUC-Dor-030869	Dipodomys ordii	42.30	4.00e-101	362.00
IUUC-Dme-032096	Drosophila melanogaster	22.61	4.00e-31	131.00
IUUC-Ete-033059	Echinops telfairi	39.02	9.00e-92	332.00
IUUC-Eca-033718	Equus caballus	40.38	0.00e+00	1154.00
IUUC-Fca-035748	Felis catus	41.51	0.00e+00	1134.00
IUUC-Gac-041507	Gasterosteus aculeatus	44.70	0.00e+00	1103.00
IUUC-Ggo-044551	Gorilla gorilla	39.42	0.00e+00	1101.00
IUUC-Hsa-046787	Homo sapiens	40.82	0.00e+00	1181.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	36.50	7.00e-167	582.00
IUUC-Lch-049578	Latimeria chalumnae	53.53	0.00e+00	1655.00
IUUC-Laf-054240	Loxodonta africana	41.79	0.00e+00	1253.00
IUUC-Mcc-054657	Macaca mulatta	36.47	0.00e+00	937.00
IUUC-Meu-056591	Macropus eugenii	42.98	0.00e+00	696.00
IUUC-Mmr-061577	Microcebus murinus	40.76	0.00e+00	1142.00
IUUC-Mdo-062895	Monodelphis domestica	44.18	0.00e+00	1180.00
IUUC-Mmu-063866	Mus musculus	40.91	0.00e+00	1162.00
IUUC-Mpu-066510	Mustela putorius furo	41.36	0.00e+00	1219.00
IUUC-Mlu-067855	Myotis lucifugus	41.44	0.00e+00	1172.00
IUUC-Nle-069557	Nomascus leucogenys	39.11	0.00e+00	1071.00
IUUC-Opr-071196	Ochotona princeps	36.27	6.00e-85	309.00
IUUC-Ont-072070	Oreochromis niloticus	45.15	0.00e+00	1226.00
IUUC-Oan-073437	Ornithorhynchus anatinus	44.97	0.00e+00	932.00
IUUC-Ocu-074941	Oryctolagus cuniculus	42.52	4.00e-29	121.00
IUUC-Ola-086624	Oryzias latipes	42.89	0.00e+00	1063.00
IUUC-Oga-088313	Otolemur garnettii	41.66	0.00e+00	1100.00
IUUC-Oar-090123	Ovis aries	41.09	0.00e+00	1192.00
IUUC-Ptr-090552	Pan troglodytes	37.50	8.00e-122	432.00
IUUC-Psi-093963	Pelodiscus sinensis	46.21	0.00e+00	1349.00
IUUC-Pfo-096197	Poecilia formosa	42.87	0.00e+00	1177.00
IUUC-Pab-097755	Pongo abelii	37.61	1.00e-103	370.00
IUUC-Pca-100809	Procavia capensis	39.62	5.00e-158	552.00
IUUC-Pva-102554	Pteropus vampyrus	39.65	0.00e+00	987.00
IUUC-Rno-105174	Rattus norvegicus	37.60	0.00e+00	974.00
IUUC-Sha-107304	Sarcophilus harrisii	44.72	0.00e+00	1353.00
IUUC-Sar-113168	Sorex araneus	38.45	9.00e-131	461.00
IUUC-Tru-118251	Takifugu rubripes	42.60	0.00e+00	980.00
IUUC-Tsy-119276	Tarsius syrichta	38.81	6.00e-46	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence