iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000189152.10	ENST00000344415.8	ENSP00000437409.2
ENSG00000189152.10	ENST00000574324.1	ENSP00000459618.1
ENSG00000189152.10	ENST00000583540.1	ENSP00000464934.1

Annotation

Cancer Mutation
ICGC	COSMIC	CGAP
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
AREsite	microRNA	TRANSFAC	TargetScan
miRcode	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
BioGRID
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-14	55.3	4	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +ly+++a+++deL ++kGd+++++ + e d++W k+  el+g +G++P+n+++
   Q: 4    VALYSFQATESDELAFNKGDTLKIL-NMEDDQNWYKA--ELRGVEGFIPKNYIR 54
           58***********************.99*******99..9************97 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MESVALYSFQ ATESDELAFN KGDTLKILNM EDDQNWYKAE LRGVEGFIPK NYIRVKPHPW 60
YSGRISRQLA EEILMKRNHL GAFLIRESES SPGEFSVSVN NRAQRGPCLG PKSHSRLG 118

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGTTTCTC CCCCATCAGG AGCAGTTTCA GTCTCAACTT CAAAAGAACA AACGCGCACT 60
CAAAACAAAG GAAGACCGTC CTCGACTGCA GAGGAAGCAG GAAGCTGTCG GCCCAGCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain