iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047574

Ensembl Protein ID

MLOC_58751.1

UniProt Accession

F2DK11; F2DK11_HORVV

Genbank Protein ID

BAJ95432.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

AK364229

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_58751	MLOC_58751.1	MLOC_58751.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.15	1.00e-40	163.00	IUUC-Dme-031700
E3 activity/RING/RING	36.73	5.00e-43	172.00	IUUC-Hsa-046357
E3 activity/RING/RING	37.00	3.00e-43	172.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Hordeum vulgare

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPGSSIVSV TEVPESDCGD RGLSESLSST RLDGDSTSKP SWAASLVNVG LSSLTGLNDL 60
LECPVCTNSM RPPILQCPNG HTICSSCKHR VDNHCPTCRQ ELGNIRCLAL EKVAESIQLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCCCACGG GCGCCGGTGC TGCCGCTGGG CCGGCGTGGA TCGGAGGAGA TCCGCCCCCG 60
ACCTGGGATG ATACCTTCGT TCGCTGGTGA GGAGCCCTAG GCTTGGCTGC ACGGGATTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	99.04	0.00e+00	645.00
IUUC-Aml-001186	Ailuropoda melanoleuca	37.02	4.00e-45	173.00
IUUC-Atr-003118	Amborella trichopoda	68.99	6.00e-120	422.00
IUUC-Apl-003813	Anas platyrhynchos	37.00	8.00e-45	172.00
IUUC-Aca-005014	Anolis carolinensis	37.00	1.00e-44	172.00
IUUC-Aly-006207	Arabidopsis lyrata	68.05	9.00e-129	451.00
IUUC-Ath-007049	Arabidopsis thaliana	68.17	3.00e-128	449.00
IUUC-Acl-008349	Aspergillus clavatus	29.41	4.00e-06	44.70
IUUC-Ani-009190	Aspergillus nidulans	27.35	2.00e-05	42.00
IUUC-Ame-011196	Astyanax mexicanus	36.96	4.00e-46	176.00
IUUC-Bta-012887	Bos taurus	37.02	5.00e-45	173.00
IUUC-Bdi-014200	Brachypodium distachyon	96.78	1.00e-180	623.00
IUUC-Bol-015523	Brassica oleracea	76.34	7.00e-124	435.00
IUUC-Bra-017336	Brassica rapa	77.39	6.00e-125	439.00
IUUC-Cel-018320	Caenorhabditis elegans	33.47	5.00e-35	140.00
IUUC-Cja-019796	Callithrix jacchus	36.73	8.00e-45	172.00
IUUC-Cfa-020642	Canis familiaris	36.73	4.00e-45	173.00
IUUC-Cpo-022348	Cavia porcellus	37.00	8.00e-45	172.00
IUUC-Csa-023974	Chlorocebus sabaeus	36.73	9.00e-45	172.00
IUUC-Cho-024933	Choloepus hoffmanni	35.46	2.00e-40	157.00
IUUC-Cin-025674	Ciona intestinalis	35.98	3.00e-42	163.00
IUUC-Csv-026233	Ciona savignyi	36.40	3.00e-42	164.00
IUUC-Dre-028041	Danio rerio	36.96	5.00e-46	176.00
IUUC-Dno-029764	Dasypus novemcinctus	37.00	1.00e-44	172.00
IUUC-Dor-030489	Dipodomys ordii	30.81	2.00e-20	90.50
IUUC-Dme-031700	Drosophila melanogaster	35.60	1.00e-37	148.00
IUUC-Ete-032423	Echinops telfairi	37.27	2.00e-44	171.00
IUUC-Eca-033536	Equus caballus	37.00	8.00e-45	172.00
IUUC-Eeu-035314	Erinaceus europaeus	36.18	1.00e-44	172.00
IUUC-Fca-035362	Felis catus	36.73	8.00e-45	172.00
IUUC-Fal-037487	Ficedula albicollis	36.69	2.00e-45	174.00
IUUC-Gmo-039091	Gadus morhua	35.06	9.00e-39	152.00
IUUC-Gga-040269	Gallus gallus	37.00	8.00e-45	172.00
IUUC-Gac-042282	Gasterosteus aculeatus	37.00	2.00e-45	174.00
IUUC-Gma-042926	Glycine max	72.30	3.00e-122	429.00
IUUC-Ggo-045444	Gorilla gorilla	36.73	9.00e-45	172.00
IUUC-Hsa-046357	Homo sapiens	36.73	9.00e-45	172.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	37.00	8.00e-45	172.00
IUUC-Lch-049504	Latimeria chalumnae	37.36	2.00e-45	174.00
IUUC-Lpe-050879	Leersia perrieri	92.28	5.00e-165	572.00
IUUC-Loc-052191	Lepisosteus oculatus	36.96	2.00e-45	174.00
IUUC-Laf-053668	Loxodonta africana	37.00	8.00e-45	172.00
IUUC-Mcc-054640	Macaca mulatta	36.73	9.00e-45	172.00
IUUC-Meu-055922	Macropus eugenii	35.06	3.00e-39	154.00
IUUC-Mtr-058699	Medicago truncatula	76.43	3.00e-124	436.00
IUUC-Mga-059503	Meleagris gallopavo	37.00	1.00e-44	171.00
IUUC-Mmr-060794	Microcebus murinus	37.00	8.00e-45	172.00
IUUC-Mdo-061971	Monodelphis domestica	35.86	1.00e-40	158.00
IUUC-Mmu-064129	Mus musculus	37.00	6.00e-45	172.00
IUUC-Mac-065014	Musa acuminata	75.46	8.00e-127	444.00
IUUC-Mpu-066488	Mustela putorius furo	36.73	9.00e-45	172.00
IUUC-Mlu-067207	Myotis lucifugus	36.81	7.00e-45	172.00
IUUC-Nle-069706	Nomascus leucogenys	36.73	8.00e-45	172.00
IUUC-Opr-070341	Ochotona princeps	26.58	2.00e-11	61.60
IUUC-Ont-071849	Oreochromis niloticus	37.00	2.00e-45	174.00
IUUC-Oan-073701	Ornithorhynchus anatinus	24.83	3.00e-11	60.80
IUUC-Ocu-074876	Oryctolagus cuniculus	36.73	1.00e-44	172.00
IUUC-Oba-075454	Oryza barthii	90.68	3.00e-163	565.00
IUUC-Obr-076037	Oryza brachyantha	67.20	1.00e-121	427.00
IUUC-Ogl-077712	Oryza glaberrima	90.68	3.00e-163	565.00
IUUC-Ogu-078910	Oryza glumaepatula	90.68	2.00e-163	566.00
IUUC-Oin-079749	Oryza indica	90.68	3.00e-163	565.00
IUUC-Olo-080244	Oryza longistaminata	65.92	9.00e-122	429.00
IUUC-Ome-081318	Oryza meridionalis	91.32	1.00e-163	567.00
IUUC-Oni-083109	Oryza nivara	90.68	3.00e-163	565.00
IUUC-Opu-084065	Oryza punctata	91.00	2.00e-163	566.00
IUUC-Oru-084785	Oryza rufipogon	90.68	3.00e-163	565.00
IUUC-Osa-085610	Oryza sativa	90.68	3.00e-163	565.00
IUUC-Ola-086814	Oryzias latipes	37.00	2.00e-45	174.00
IUUC-Oga-088114	Otolemur garnettii	37.19	6.00e-45	172.00
IUUC-Oar-089323	Ovis aries	36.33	9.00e-45	172.00
IUUC-Ptr-090692	Pan troglodytes	37.00	1.00e-44	171.00
IUUC-Pan-092012	Papio anubis	36.73	9.00e-45	172.00
IUUC-Psi-093687	Pelodiscus sinensis	36.73	8.00e-45	172.00
IUUC-Pma-094387	Petromyzon marinus	37.23	4.00e-46	176.00
IUUC-Ppa-095212	Physcomitrella patens	77.04	4.00e-123	432.00
IUUC-Pfo-097134	Poecilia formosa	37.00	2.00e-45	174.00
IUUC-Pab-097555	Pongo abelii	36.73	9.00e-45	172.00
IUUC-Pop-100033	Populus trichocarpa	77.78	7.00e-126	441.00
IUUC-Pca-100328	Procavia capensis	35.32	2.00e-37	148.00
IUUC-Ppe-101960	Prunus persica	77.57	2.00e-126	444.00
IUUC-Pva-102368	Pteropus vampyrus	30.77	3.00e-10	57.80
IUUC-Rno-104866	Rattus norvegicus	37.00	6.00e-45	172.00
IUUC-Sha-106547	Sarcophilus harrisii	37.02	6.00e-45	173.00
IUUC-Smo-109412	Selaginella moellendorffii	69.23	8.00e-126	441.00
IUUC-Sit-110595	Setaria italica	89.39	3.00e-169	585.00
IUUC-Sly-111259	Solanum lycopersicum	77.57	2.00e-125	440.00
IUUC-Stu-112571	Solanum tuberosum	77.95	1.00e-125	441.00
IUUC-Sbi-114090	Sorghum bicolor	88.78	3.00e-166	576.00
IUUC-Ssc-116441	Sus scrofa	36.51	2.00e-40	157.00
IUUC-Tgu-116579	Taeniopygia guttata	37.00	8.00e-45	172.00
IUUC-Tru-118250	Takifugu rubripes	37.08	3.00e-44	170.00
IUUC-Tsy-119548	Tarsius syrichta	30.21	3.00e-07	47.00
IUUC-Tni-120488	Tetraodon nigroviridis	37.09	1.00e-42	165.00
IUUC-Tca-121228	Theobroma cacao	73.21	1.00e-126	444.00
IUUC-Tae-123647	Triticum aestivum	99.04	0.00e+00	645.00
IUUC-Tur-126259	Triticum urartu	66.12	1.00e-120	424.00
IUUC-Ttr-129166	Tursiops truncatus	38.59	5.00e-41	160.00
IUUC-Vpa-130799	Vicugna pacos	32.16	1.00e-19	87.80
IUUC-Vvi-131233	Vitis vinifera	67.42	1.00e-123	434.00
IUUC-Xtr-132553	Xenopus tropicalis	37.00	9.00e-45	172.00
IUUC-Xma-133670	Xiphophorus maculatus	37.00	2.00e-45	174.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence