iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120488

Ensembl Protein ID

ENSTNIP00000006572.1

UniProt Accession

H3CE98; H3CE98_TETNG

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000003964.1	ENSTNIT00000006723.1	ENSTNIP00000006572.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	81.96	5.00e-123	437.00	IUUC-Dme-031700
E3 activity/RING/RING	97.16	8.00e-163	570.00	IUUC-Hsa-046357
E3 activity/RING/RING	97.52	4.00e-163	570.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Tetraodon nigroviridis

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MSRQTATALP TGTSKCPPSQ RVPTLSGTTA SNSDLASLFE CPVCFDYVLP PILQCQSGHL 60
VCSNCRPKLT CCPTCRGPLG SIRNLAMEKV ANSVLFPCKY ASSGCEVTLP HTEKTEHEEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTCGCC AGACCGCCAC CGCGCTGCCC ACAGGAACCT CCAAGTGTCC TCCCTCCCAG 60
CGCGTGCCCA CCCTGTCGGG CACCACGGCC TCCAACAGCG ACCTGGCCAG CCTCTTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	37.45	2.00e-42	166.00
IUUC-Aml-001186	Ailuropoda melanoleuca	96.81	4.00e-163	566.00
IUUC-Atr-002857	Amborella trichopoda	37.07	4.00e-42	164.00
IUUC-Apl-003813	Anas platyrhynchos	96.81	3.00e-163	566.00
IUUC-Aca-005014	Anolis carolinensis	96.81	2.00e-163	567.00
IUUC-Aly-006522	Arabidopsis lyrata	37.90	3.00e-39	155.00
IUUC-Ath-007049	Arabidopsis thaliana	33.10	3.00e-39	155.00
IUUC-Ame-011196	Astyanax mexicanus	97.87	7.00e-165	572.00
IUUC-Bta-012887	Bos taurus	96.81	3.00e-163	566.00
IUUC-Bdi-014200	Brachypodium distachyon	37.82	4.00e-43	168.00
IUUC-Bol-016263	Brassica oleracea	33.45	5.00e-40	157.00
IUUC-Bra-016910	Brassica rapa	37.35	2.00e-39	155.00
IUUC-Cel-018320	Caenorhabditis elegans	71.60	4.00e-112	397.00
IUUC-Cja-019796	Callithrix jacchus	97.16	6.00e-164	569.00
IUUC-Cfa-020642	Canis familiaris	96.81	5.00e-164	569.00
IUUC-Cpo-022348	Cavia porcellus	97.16	5.00e-164	569.00
IUUC-Csa-023974	Chlorocebus sabaeus	97.16	3.00e-164	570.00
IUUC-Cin-025674	Ciona intestinalis	78.01	3.00e-131	460.00
IUUC-Csv-026233	Ciona savignyi	84.25	6.00e-129	452.00
IUUC-Dre-028041	Danio rerio	98.23	8.00e-166	575.00
IUUC-Dno-029764	Dasypus novemcinctus	96.81	4.00e-163	566.00
IUUC-Dme-031700	Drosophila melanogaster	83.87	7.00e-117	413.00
IUUC-Ete-032423	Echinops telfairi	96.24	2.00e-152	531.00
IUUC-Eca-033536	Equus caballus	96.81	3.00e-163	566.00
IUUC-Eeu-035314	Erinaceus europaeus	96.24	1.00e-152	532.00
IUUC-Fca-035362	Felis catus	96.81	2.00e-163	567.00
IUUC-Fal-037487	Ficedula albicollis	96.81	3.00e-163	566.00
IUUC-Gga-040269	Gallus gallus	96.81	3.00e-163	566.00
IUUC-Gac-042282	Gasterosteus aculeatus	98.94	5.00e-166	576.00
IUUC-Gma-042926	Glycine max	34.43	1.00e-38	153.00
IUUC-Ggo-045444	Gorilla gorilla	97.16	3.00e-164	570.00
IUUC-Hsa-046357	Homo sapiens	97.16	3.00e-164	570.00
IUUC-Hvu-047574	Hordeum vulgare	37.09	2.00e-42	165.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	97.16	5.00e-164	569.00
IUUC-Lch-049504	Latimeria chalumnae	96.81	3.00e-163	566.00
IUUC-Lpe-050879	Leersia perrieri	40.00	5.00e-41	161.00
IUUC-Loc-052191	Lepisosteus oculatus	97.16	3.00e-163	567.00
IUUC-Laf-053668	Loxodonta africana	96.81	3.00e-163	566.00
IUUC-Mcc-054640	Macaca mulatta	97.16	3.00e-164	570.00
IUUC-Mtr-058747	Medicago truncatula	34.80	6.00e-40	157.00
IUUC-Mga-059503	Meleagris gallopavo	96.81	2.00e-163	567.00
IUUC-Mmr-060794	Microcebus murinus	97.16	5.00e-164	569.00
IUUC-Mmu-064129	Mus musculus	97.52	2.00e-164	570.00
IUUC-Mac-065014	Musa acuminata	36.43	4.00e-40	158.00
IUUC-Mpu-066488	Mustela putorius furo	96.81	3.00e-163	566.00
IUUC-Mlu-067207	Myotis lucifugus	96.81	1.00e-163	568.00
IUUC-Nle-069706	Nomascus leucogenys	97.16	5.00e-164	569.00
IUUC-Ont-071849	Oreochromis niloticus	98.94	5.00e-166	576.00
IUUC-Ocu-074876	Oryctolagus cuniculus	97.16	7.00e-164	569.00
IUUC-Oba-075454	Oryza barthii	40.42	6.00e-41	160.00
IUUC-Obr-076037	Oryza brachyantha	35.92	5.00e-38	151.00
IUUC-Ogl-077712	Oryza glaberrima	40.42	6.00e-41	160.00
IUUC-Ogu-078910	Oryza glumaepatula	40.42	1.00e-40	160.00
IUUC-Oin-079749	Oryza indica	40.42	6.00e-41	160.00
IUUC-Olo-080244	Oryza longistaminata	35.92	6.00e-38	151.00
IUUC-Ome-081318	Oryza meridionalis	40.42	6.00e-41	160.00
IUUC-Oni-083109	Oryza nivara	40.42	6.00e-41	160.00
IUUC-Opu-084065	Oryza punctata	40.83	3.00e-41	161.00
IUUC-Oru-084785	Oryza rufipogon	40.42	6.00e-41	160.00
IUUC-Osa-085610	Oryza sativa	40.42	6.00e-41	160.00
IUUC-Ola-086814	Oryzias latipes	98.94	5.00e-166	576.00
IUUC-Oga-088399	Otolemur garnettii	97.16	5.00e-164	569.00
IUUC-Oar-089323	Ovis aries	96.81	5.00e-163	566.00
IUUC-Ptr-090692	Pan troglodytes	97.16	4.00e-164	570.00
IUUC-Pan-092012	Papio anubis	97.16	3.00e-164	570.00
IUUC-Psi-093687	Pelodiscus sinensis	96.81	1.00e-163	568.00
IUUC-Pma-094387	Petromyzon marinus	92.23	3.00e-154	536.00
IUUC-Ppa-095212	Physcomitrella patens	36.29	2.00e-38	152.00
IUUC-Pfo-097134	Poecilia formosa	98.94	5.00e-166	576.00
IUUC-Pab-097555	Pongo abelii	97.16	3.00e-164	570.00
IUUC-Pop-099970	Populus trichocarpa	36.59	5.00e-42	164.00
IUUC-Ppe-101760	Prunus persica	35.87	2.00e-41	162.00
IUUC-Rno-104866	Rattus norvegicus	97.52	2.00e-164	570.00
IUUC-Sha-106547	Sarcophilus harrisii	96.81	2.00e-163	567.00
IUUC-Smo-109412	Selaginella moellendorffii	34.67	1.00e-37	149.00
IUUC-Sit-110595	Setaria italica	38.46	2.00e-39	155.00
IUUC-Sly-111259	Solanum lycopersicum	36.36	1.00e-38	153.00
IUUC-Stu-112474	Solanum tuberosum	36.21	2.00e-39	155.00
IUUC-Sbi-114090	Sorghum bicolor	37.50	8.00e-40	157.00
IUUC-Tgu-116579	Taeniopygia guttata	96.81	3.00e-163	566.00
IUUC-Tru-118250	Takifugu rubripes	94.33	8.00e-157	545.00
IUUC-Tca-121228	Theobroma cacao	37.14	2.00e-39	155.00
IUUC-Tae-123647	Triticum aestivum	37.45	2.00e-42	166.00
IUUC-Tur-126049	Triticum urartu	37.90	1.00e-36	146.00
IUUC-Ttr-129166	Tursiops truncatus	96.27	5.00e-137	480.00
IUUC-Vvi-131451	Vitis vinifera	37.55	3.00e-39	155.00
IUUC-Xtr-132553	Xenopus tropicalis	97.16	5.00e-164	569.00
IUUC-Xma-133670	Xiphophorus maculatus	98.94	5.00e-166	576.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence