iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000012823.4	ENSCAFT00000045813.2	ENSCAFP00000040614.1
ENSCAFG00000012823.4	ENSCAFT00000020380.3	ENSCAFP00000018910.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-25	87.9	581	611
UBD/Beta-Prp	9.30e-54	182.9	570	790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd..tllvsGsdDgtikvWDl 30
           Htd v++la+s+  + l+s+s Dgt+++W++
   Q: 581  HTDAVWGLAYSGikNQLLSCSADGTVRLWNP 611
           **********666689*************95 PP

UBD/Beta-Prp

   S: 40   ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsv..lslsfsp.sgdklvsGshdrtirvwdle 124
           ++  l  +l  h+++v+ + +s  ++ l+++s D+t+++w+++ + +c+ t++g ++    +s++f   +  ++v+  +     ++dle
   Q: 570  EPNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQeKLPCICTYNGDKEHGipTSVDFIGcDPAHMVTSFNTGSTVIYDLE 658
           455678899*******************************887699*******7655541245555554449999999999999***** PP
   S: 125  tgqclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
           t q l           + ++ +n vv+hp+  + ++++ Dr ++++d ktgk+++ +   h d+v+sl++d+ng +l+sgs+d +++lw
   Q: 659  TSQSLVMlssqidSGLQSNKHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVA-HLDAVTSLAVDPNGIYLMSGSHDCSIRLW 746
           *****999999664445778899******99**************************98.***************************** PP
   S: 208  dlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           +l +++cv++ ++h+    + +++v+f+p + +++s+++D   +
   Q: 747  NLDSKTCVQEITAHRkkldESIYDVAFHPSKAYIASAGADALAK 790
           ***************99999*******************97655 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDELAGGGGG GPGMAAPPRQ QQGPGGNMSL SPGGNGAAGG GGPPAAEGAG PAAGPELSRP 60
QQYTIPGILH YIQHEWARFE MERAHWEVER AELQARIAFL QGERKGQENL KKDLVRRIKM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGAGCCAGG AAACCCAAAA CCCCAACCCG GCACCCGGGC CCGAAGGGGC TGGGCTATCT 60
GCCAAAAGAG AACGTCCATC CCCAAAGCCT CAGGAATGAC GGGTACTTAG AGCGAGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0000159--C:protein phosphatase type 2A complex

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002046	Ailuropoda melanoleuca	94.91	0.00e+00	1335.00
IUUC-Apl-003472	Anas platyrhynchos	91.95	0.00e+00	1211.00
IUUC-Aca-005286	Anolis carolinensis	91.54	0.00e+00	1269.00
IUUC-Afl-008585	Aspergillus flavus	27.42	1.00e-35	145.00
IUUC-Ani-009405	Aspergillus nidulans	30.38	2.00e-35	144.00
IUUC-Aor-009982	Aspergillus oryzae	27.42	1.00e-35	145.00
IUUC-Bgr-012143	Blumeria graminis	25.89	1.00e-34	142.00
IUUC-Bta-012797	Bos taurus	95.36	0.00e+00	1349.00
IUUC-Bci-013742	Botrytis cinerea	25.62	4.00e-35	143.00
IUUC-Cel-018443	Caenorhabditis elegans	45.13	3.00e-101	362.00
IUUC-Cja-018786	Callithrix jacchus	94.62	0.00e+00	1319.00
IUUC-Cpo-022357	Cavia porcellus	91.94	0.00e+00	1272.00
IUUC-Csa-023725	Chlorocebus sabaeus	94.87	0.00e+00	1321.00
IUUC-Cho-024338	Choloepus hoffmanni	89.05	0.00e+00	1140.00
IUUC-Cin-025167	Ciona intestinalis	50.07	0.00e+00	662.00
IUUC-Csv-026143	Ciona savignyi	51.60	0.00e+00	670.00
IUUC-Cgl-026487	Colletotrichum gloeosporioides	26.13	3.00e-31	130.00
IUUC-Cne-026783	Cryptococcus neoformans	32.79	2.00e-57	217.00
IUUC-Dno-029926	Dasypus novemcinctus	94.47	0.00e+00	1316.00
IUUC-Dse-031486	Dothistroma septosporum	27.71	9.00e-38	152.00
IUUC-Dme-032158	Drosophila melanogaster	64.13	2.00e-144	506.00
IUUC-Ete-032770	Echinops telfairi	83.47	0.00e+00	1146.00
IUUC-Eca-033309	Equus caballus	95.16	0.00e+00	1323.00
IUUC-Eeu-034939	Erinaceus europaeus	92.50	0.00e+00	963.00
IUUC-Fca-035719	Felis catus	93.69	0.00e+00	1225.00
IUUC-Fal-037408	Ficedula albicollis	91.63	0.00e+00	1156.00
IUUC-Fox-037678	Fusarium oxysporum	26.67	2.00e-36	147.00
IUUC-Fso-038364	Fusarium solani	27.04	1.00e-37	151.00
IUUC-Gmo-039653	Gadus morhua	63.22	0.00e+00	870.00
IUUC-Ggr-039846	Gaeumannomyces graminis	26.02	3.00e-34	140.00
IUUC-Gga-041218	Gallus gallus	92.62	0.00e+00	1298.00
IUUC-Gac-042142	Gasterosteus aculeatus	72.69	0.00e+00	1055.00
IUUC-Ggo-045607	Gorilla gorilla	76.01	0.00e+00	975.00
IUUC-Hsa-045717	Homo sapiens	94.60	0.00e+00	1329.00
IUUC-Itr-048177	Ictidomys tridecemlineatus	93.27	0.00e+00	909.00
IUUC-Lch-050441	Latimeria chalumnae	87.79	0.00e+00	1274.00
IUUC-Loc-052193	Lepisosteus oculatus	83.69	0.00e+00	1215.00
IUUC-Lma-053183	Leptosphaeria maculans	28.94	5.00e-39	156.00
IUUC-Laf-053964	Loxodonta africana	94.48	0.00e+00	1299.00
IUUC-Mcc-055639	Macaca mulatta	94.88	0.00e+00	1323.00
IUUC-Mor-057148	Magnaporthe oryzae	42.31	1.00e-17	85.10
IUUC-Mpo-057337	Magnaporthe poae	25.07	3.00e-30	127.00
IUUC-Mla-058988	Melampsora laricipopulina	34.31	2.00e-64	241.00
IUUC-Mmr-061084	Microcebus murinus	95.28	0.00e+00	1330.00
IUUC-Mdo-063016	Monodelphis domestica	93.94	0.00e+00	1318.00
IUUC-Mmu-063914	Mus musculus	93.55	0.00e+00	1325.00
IUUC-Mpu-066348	Mustela putorius furo	91.19	0.00e+00	1289.00
IUUC-Mlu-067303	Myotis lucifugus	91.56	0.00e+00	1264.00
IUUC-Ncr-068831	Neurospora crassa	38.61	1.00e-21	98.60
IUUC-Nle-070032	Nomascus leucogenys	94.60	0.00e+00	1330.00
IUUC-Opr-070496	Ochotona princeps	91.42	0.00e+00	652.00
IUUC-Ont-072075	Oreochromis niloticus	72.00	0.00e+00	1050.00
IUUC-Oan-072822	Ornithorhynchus anatinus	92.35	0.00e+00	1163.00
IUUC-Ocu-073876	Oryctolagus cuniculus	91.70	0.00e+00	1300.00
IUUC-Ola-086321	Oryzias latipes	69.64	0.00e+00	995.00
IUUC-Oga-088045	Otolemur garnettii	95.26	0.00e+00	1324.00
IUUC-Oar-089737	Ovis aries	94.61	0.00e+00	1235.00
IUUC-Ptr-090871	Pan troglodytes	94.45	0.00e+00	1250.00
IUUC-Pan-092139	Papio anubis	94.18	0.00e+00	1224.00
IUUC-Psi-093424	Pelodiscus sinensis	92.36	0.00e+00	1231.00
IUUC-Pma-094286	Petromyzon marinus	66.93	0.00e+00	660.00
IUUC-Pno-094905	Phaeosphaeria nodorum	28.16	2.00e-35	144.00
IUUC-Pfo-096564	Poecilia formosa	72.97	0.00e+00	1066.00
IUUC-Pab-098626	Pongo abelii	94.60	0.00e+00	1366.00
IUUC-Pca-101047	Procavia capensis	86.86	1.00e-159	556.00
IUUC-Pva-102445	Pteropus vampyrus	88.96	0.00e+00	1211.00
IUUC-Pgr-103483	Puccinia graminis	36.71	4.00e-55	210.00
IUUC-Ptt-103828	Puccinia triticina	37.12	5.00e-49	190.00
IUUC-Pte-104374	Pyrenophora teres	28.11	2.00e-33	137.00
IUUC-Pyt-104568	Pyrenophora triticirepentis	27.65	1.00e-36	148.00
IUUC-Rno-105999	Rattus norvegicus	92.19	0.00e+00	1339.00
IUUC-Sha-106786	Sarcophilus harrisii	91.94	0.00e+00	1233.00
IUUC-Ssl-108495	Sclerotinia sclerotiorum	26.30	8.00e-35	142.00
IUUC-Sar-113296	Sorex araneus	77.96	0.00e+00	865.00
IUUC-Sre-115115	Sporisorium reilianum	34.96	1.00e-63	238.00
IUUC-Tgu-117199	Taeniopygia guttata	88.14	0.00e+00	1132.00
IUUC-Tsy-119356	Tarsius syrichta	78.44	0.00e+00	907.00
IUUC-Tre-122113	Trichoderma reesei	28.26	2.00e-38	154.00
IUUC-Tvi-122312	Trichoderma virens	26.46	1.00e-36	148.00
IUUC-Tme-126990	Tuber melanosporum	27.12	5.00e-35	143.00
IUUC-Tbe-127691	Tupaia belangeri	76.06	0.00e+00	730.00
IUUC-Ttr-128600	Tursiops truncatus	86.64	0.00e+00	1207.00
IUUC-Uma-129659	Ustilago maydis	34.13	4.00e-64	239.00
IUUC-Vda-129673	Verticillium dahliae	25.48	9.00e-31	129.00
IUUC-Xtr-132330	Xenopus tropicalis	80.83	0.00e+00	1172.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence