iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA
DNA & RNA Element
UTRdb	AREsite	miRTarBase	microRNA
TRANSFAC	TargetScan	SomamiR	miRcode
RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.40e-06	30.1	27	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 95   eegpdaglldrlpeeilveilklldkeellraarvcrrwq.elasqkalwktv 146
           +++++++ ++ lp ei ++i++ ld ++l+ra+++cr+w+ ++ ++++lwk  
   Q: 27   KNESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWNdTIRNSDSLWKPH 79
           4677889999******************************8888899999975 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MHKNSKRNNN LRVSHTEANS VDAEKEKNES QNNFFELLPA EITFKIFSQL DIRSLCRASL 60
TCRSWNDTIR NSDSLWKPHC MTVRAVCRRE IDDDLESGYS WRVILLRNYQ KSKVKHEWLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAATTCCGG TGGATTTAAA TCGCGGGAGG AGAAGCTACC GCGGCCTAGT AGGTAGAAGG 60
GTCTTCCGTT CCCGTTGGCT TAGGTGTCTA CGCTCCCGGG GACGCGGCCT GGACGCAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

KEGG

hsa:554251

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001692	Ailuropoda melanoleuca	88.11	2.00e-74	270.00
IUUC-Apl-003195	Anas platyrhynchos	62.58	5.00e-52	196.00
IUUC-Aca-004788	Anolis carolinensis	66.92	4.00e-51	192.00
IUUC-Bta-012537	Bos taurus	86.45	3.00e-76	276.00
IUUC-Cja-019552	Callithrix jacchus	89.51	3.00e-74	270.00
IUUC-Cfa-020875	Canis familiaris	77.38	2.00e-36	144.00
IUUC-Cpo-021823	Cavia porcellus	85.81	7.00e-78	282.00
IUUC-Csa-023619	Chlorocebus sabaeus	93.55	4.00e-78	283.00
IUUC-Cho-024815	Choloepus hoffmanni	85.81	3.00e-75	273.00
IUUC-Dor-030194	Dipodomys ordii	78.71	2.00e-70	257.00
IUUC-Eca-033364	Equus caballus	85.81	7.00e-77	279.00
IUUC-Fca-035814	Felis catus	85.16	2.00e-77	280.00
IUUC-Fal-036928	Ficedula albicollis	64.52	4.00e-45	172.00
IUUC-Gga-040245	Gallus gallus	57.42	1.00e-48	185.00
IUUC-Gac-041831	Gasterosteus aculeatus	51.95	3.00e-42	164.00
IUUC-Ggo-045464	Gorilla gorilla	98.71	5.00e-83	299.00
IUUC-Itr-049061	Ictidomys tridecemlineatus	89.68	1.00e-78	284.00
IUUC-Lch-049672	Latimeria chalumnae	52.76	5.00e-32	129.00
IUUC-Loc-052597	Lepisosteus oculatus	53.55	8.00e-45	172.00
IUUC-Laf-054453	Loxodonta africana	81.29	7.00e-73	265.00
IUUC-Mcc-055343	Macaca mulatta	94.19	7.00e-79	285.00
IUUC-Mga-059631	Meleagris gallopavo	58.06	5.00e-48	182.00
IUUC-Mdo-062604	Monodelphis domestica	67.74	2.00e-59	221.00
IUUC-Mmu-063222	Mus musculus	75.48	9.00e-69	252.00
IUUC-Nle-069650	Nomascus leucogenys	97.90	3.00e-81	293.00
IUUC-Opr-070720	Ochotona princeps	83.33	4.00e-70	256.00
IUUC-Ont-071309	Oreochromis niloticus	48.20	6.00e-37	146.00
IUUC-Oan-073265	Ornithorhynchus anatinus	59.49	3.00e-51	194.00
IUUC-Ocu-074967	Oryctolagus cuniculus	84.52	1.00e-75	275.00
IUUC-Olu-087621	Ostreococcus lucimarinus	40.48	3.00e-03	38.10
IUUC-Oar-090070	Ovis aries	87.10	8.00e-78	282.00
IUUC-Ptr-090920	Pan troglodytes	98.71	3.00e-88	317.00
IUUC-Pan-092170	Papio anubis	93.55	4.00e-78	283.00
IUUC-Psi-093939	Pelodiscus sinensis	66.45	1.00e-57	214.00
IUUC-Pfo-096318	Poecilia formosa	55.65	4.00e-38	150.00
IUUC-Pab-097968	Pongo abelii	96.77	1.00e-80	291.00
IUUC-Pca-100414	Procavia capensis	85.83	4.00e-63	232.00
IUUC-Pva-102518	Pteropus vampyrus	73.61	3.00e-59	220.00
IUUC-Rno-106002	Rattus norvegicus	70.59	7.00e-63	232.00
IUUC-Sha-107402	Sarcophilus harrisii	72.90	2.00e-61	227.00
IUUC-Smo-109618	Selaginella moellendorffii	45.45	2.00e-03	38.10
IUUC-Ssc-116238	Sus scrofa	85.16	7.00e-75	272.00
IUUC-Tru-118778	Takifugu rubripes	48.06	3.00e-34	137.00
IUUC-Tsy-118939	Tarsius syrichta	89.03	7.00e-80	288.00
IUUC-Tbe-128104	Tupaia belangeri	75.50	2.00e-64	237.00
IUUC-Ttr-129092	Tursiops truncatus	86.45	1.00e-76	278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence