iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000002882.2	ENSCJAT00000005650.2	ENSCJAP00000005356.2
ENSCJAG00000002882.2	ENSCJAT00000005774.2	ENSCJAP00000005471.2
ENSCJAG00000002882.2	ENSCJAT00000005796.2	ENSCJAP00000005492.2
ENSCJAG00000002882.2	ENSCJAT00000061430.1	ENSCJAP00000043235.1
ENSCJAG00000002882.2	ENSCJAT00000055788.1	ENSCJAP00000050553.1
ENSCJAG00000002882.2	ENSCJAT00000052247.1	ENSCJAP00000046588.1
ENSCJAG00000002882.2	ENSCJAT00000005719.1	ENSCJAP00000005418.1
ENSCJAG00000002882.2	ENSCJAT00000005773.1	ENSCJAP00000005470.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.40e-67	221.8	1159	1210

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+
   Q: 1159 QVIGMYDYIAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVK 1210
           46779**********************..8889******..9*************8 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAQFPTPFGG SLDVWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GELDQVEFSI AMKLIKLKLQ GYQLPSTLPH VMKQQPVAIS SAPALGMGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCGAGGGA GGGAGAGAAG GAGGTAGAGA GGAGTGGAGG CGCCGGGGGA GGGAGAGCAG 60
CTTGGTTGCT CCGTAGTACG GCGGCTCGCG AGGAAGAACC CCGAGCGGGC TCCGGGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	3.00e-14	75.10
IUUC-Aml-001218	Ailuropoda melanoleuca	95.79	0.00e+00	2423.00
IUUC-Apl-003335	Anas platyrhynchos	91.67	0.00e+00	2279.00
IUUC-Aca-005130	Anolis carolinensis	89.37	0.00e+00	2250.00
IUUC-Ago-007935	Ashbya gossypii	35.82	5.00e-14	72.80
IUUC-Acl-008295	Aspergillus clavatus	30.46	1.00e-15	78.60
IUUC-Ani-009403	Aspergillus nidulans	41.38	3.00e-15	73.20
IUUC-Ame-011878	Astyanax mexicanus	75.84	0.00e+00	1940.00
IUUC-Bta-012863	Bos taurus	95.63	0.00e+00	2367.00
IUUC-Bdi-014016	Brachypodium distachyon	40.00	5.00e-14	73.90
IUUC-Cfa-020272	Canis familiaris	96.35	0.00e+00	2444.00
IUUC-Cpo-021352	Cavia porcellus	88.75	0.00e+00	2882.00
IUUC-Csa-024033	Chlorocebus sabaeus	81.32	0.00e+00	1920.00
IUUC-Cho-024969	Choloepus hoffmanni	85.59	0.00e+00	1935.00
IUUC-Cin-025435	Ciona intestinalis	45.63	0.00e+00	977.00
IUUC-Csv-026290	Ciona savignyi	57.95	0.00e+00	777.00
IUUC-Cne-026918	Cryptococcus neoformans	32.92	2.00e-38	155.00
IUUC-Cme-027247	Cyanidioschyzon merolae	25.43	3.00e-11	63.20
IUUC-Dre-028623	Danio rerio	76.36	0.00e+00	1944.00
IUUC-Dno-030044	Dasypus novemcinctus	95.73	0.00e+00	2401.00
IUUC-Dor-030272	Dipodomys ordii	89.78	0.00e+00	2122.00
IUUC-Ete-032927	Echinops telfairi	98.00	0.00e+00	1033.00
IUUC-Eca-033469	Equus caballus	96.66	0.00e+00	2399.00
IUUC-Eeu-034977	Erinaceus europaeus	92.39	0.00e+00	1149.00
IUUC-Fca-036419	Felis catus	95.79	0.00e+00	2390.00
IUUC-Fal-037236	Ficedula albicollis	89.38	0.00e+00	2253.00
IUUC-Gmo-039632	Gadus morhua	70.69	0.00e+00	1689.00
IUUC-Gga-040835	Gallus gallus	89.75	0.00e+00	2244.00
IUUC-Gac-041948	Gasterosteus aculeatus	71.57	0.00e+00	1816.00
IUUC-Hsa-045699	Homo sapiens	98.97	0.00e+00	2511.00
IUUC-Hvu-047530	Hordeum vulgare	33.14	1.00e-14	75.50
IUUC-Itr-048773	Ictidomys tridecemlineatus	93.91	0.00e+00	2388.00
IUUC-Kpa-049215	Komagataella pastoris	40.00	9.00e-15	75.10
IUUC-Lch-050502	Latimeria chalumnae	78.52	0.00e+00	1642.00
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Loc-052613	Lepisosteus oculatus	81.12	0.00e+00	1976.00
IUUC-Laf-053608	Loxodonta africana	94.90	0.00e+00	2409.00
IUUC-Mcc-055720	Macaca mulatta	98.49	0.00e+00	2462.00
IUUC-Meu-056445	Macropus eugenii	85.30	0.00e+00	1712.00
IUUC-Mla-059128	Melampsora laricipopulina	33.09	4.00e-40	161.00
IUUC-Mga-059997	Meleagris gallopavo	58.89	0.00e+00	1458.00
IUUC-Mvi-060268	Microbotryum violaceum	29.67	4.00e-44	174.00
IUUC-Mmr-061258	Microcebus murinus	97.46	0.00e+00	2414.00
IUUC-Mdo-062019	Monodelphis domestica	92.38	0.00e+00	2253.00
IUUC-Mmu-063885	Mus musculus	94.52	0.00e+00	2428.00
IUUC-Mac-065649	Musa acuminata	33.61	2.00e-12	68.20
IUUC-Mpu-066431	Mustela putorius furo	64.93	0.00e+00	1298.00
IUUC-Mlu-067025	Myotis lucifugus	66.98	0.00e+00	1479.00
IUUC-Nle-069448	Nomascus leucogenys	87.97	0.00e+00	1254.00
IUUC-Opr-070441	Ochotona princeps	90.87	0.00e+00	2115.00
IUUC-Ont-071752	Oreochromis niloticus	72.84	0.00e+00	1811.00
IUUC-Oan-073390	Ornithorhynchus anatinus	88.10	0.00e+00	2175.00
IUUC-Ocu-073753	Oryctolagus cuniculus	93.82	0.00e+00	3036.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	2.00e-14	74.70
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	2.00e-14	74.70
IUUC-Oni-082167	Oryza nivara	41.67	4.00e-14	73.90
IUUC-Oru-084541	Oryza rufipogon	41.67	4.00e-14	73.90
IUUC-Ola-087489	Oryzias latipes	45.41	0.00e+00	1239.00
IUUC-Olu-087698	Ostreococcus lucimarinus	29.14	1.00e-16	81.60
IUUC-Oga-088602	Otolemur garnettii	97.06	0.00e+00	2420.00
IUUC-Oar-090195	Ovis aries	95.64	0.00e+00	2368.00
IUUC-Ptr-091363	Pan troglodytes	99.05	0.00e+00	2513.00
IUUC-Pan-092385	Papio anubis	98.34	0.00e+00	2461.00
IUUC-Psi-093136	Pelodiscus sinensis	56.66	0.00e+00	1361.00
IUUC-Pfo-097486	Poecilia formosa	74.24	0.00e+00	1852.00
IUUC-Pab-098281	Pongo abelii	87.70	0.00e+00	2127.00
IUUC-Pca-100270	Procavia capensis	79.68	0.00e+00	1344.00
IUUC-Pva-102335	Pteropus vampyrus	93.17	0.00e+00	2354.00
IUUC-Pgr-103473	Puccinia graminis	29.10	3.00e-36	148.00
IUUC-Ptt-103973	Puccinia triticina	24.54	5.00e-26	114.00
IUUC-Rno-106122	Rattus norvegicus	93.19	0.00e+00	2382.00
IUUC-Sha-106851	Sarcophilus harrisii	92.39	0.00e+00	2263.00
IUUC-Sit-110414	Setaria italica	40.48	3.00e-14	74.30
IUUC-Sbi-114170	Sorghum bicolor	38.89	2.00e-14	74.70
IUUC-Sre-115028	Sporisorium reilianum	35.41	7.00e-33	137.00
IUUC-Ssc-115562	Sus scrofa	60.33	0.00e+00	1169.00
IUUC-Tgu-117028	Taeniopygia guttata	90.33	0.00e+00	2293.00
IUUC-Tru-117789	Takifugu rubripes	75.75	0.00e+00	1875.00
IUUC-Tsy-119039	Tarsius syrichta	94.69	0.00e+00	1410.00
IUUC-Tni-119952	Tetraodon nigroviridis	74.02	0.00e+00	1741.00
IUUC-Tae-123242	Triticum aestivum	41.67	4.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	40.00	3.00e-14	73.90
IUUC-Tbe-127754	Tupaia belangeri	85.99	0.00e+00	1765.00
IUUC-Ttr-129178	Tursiops truncatus	96.58	0.00e+00	2404.00
IUUC-Uma-129456	Ustilago maydis	31.66	3.00e-32	135.00
IUUC-Vpa-130687	Vicugna pacos	92.22	0.00e+00	1199.00
IUUC-Xtr-132905	Xenopus tropicalis	86.06	0.00e+00	2182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence