iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-073753

Ensembl Protein ID

ENSOCUP00000018380.1

UniProt Accession

G1TN13; G1TN13_RABIT

Protein Name

Uncharacterized protein

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000003886.3	ENSOCUT00000024801.1	ENSOCUP00000018380.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.60e-69	228.1	1160	1211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+
   Q: 1160 QVIGMYDYTAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVK 1211
           46779**********************..8889******..9*************8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAQFPTPFGG SLDVWAITVE ERAKHDQQFH SLKPRSGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGIGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TTCCAACACC TTTTGGTGGT AAGTTTTCAA AAATTTCCTC TCTTTAATGT 60
ATTTTAAAAC ATGATATGAT GGTAAATTTT CAATGAAAAA TGTAAAGAAT AATATAATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	3.00e-14	74.70
IUUC-Aml-001218	Ailuropoda melanoleuca	93.83	0.00e+00	2356.00
IUUC-Apl-003335	Anas platyrhynchos	90.87	0.00e+00	2243.00
IUUC-Aca-005130	Anolis carolinensis	88.59	0.00e+00	2224.00
IUUC-Ago-007935	Ashbya gossypii	35.34	2.00e-14	74.30
IUUC-Ame-011878	Astyanax mexicanus	75.07	0.00e+00	1910.00
IUUC-Bta-012863	Bos taurus	94.68	0.00e+00	2328.00
IUUC-Bdi-014016	Brachypodium distachyon	40.45	6.00e-14	73.60
IUUC-Cel-018490	Caenorhabditis elegans	34.60	2.00e-43	171.00
IUUC-Cja-019012	Callithrix jacchus	95.81	0.00e+00	2343.00
IUUC-Cfa-020171	Canis familiaris	94.92	0.00e+00	2386.00
IUUC-Cpo-021352	Cavia porcellus	87.87	0.00e+00	2836.00
IUUC-Cho-024969	Choloepus hoffmanni	84.03	0.00e+00	1869.00
IUUC-Cin-025435	Ciona intestinalis	45.22	0.00e+00	972.00
IUUC-Csv-026290	Ciona savignyi	57.46	0.00e+00	771.00
IUUC-Cne-026918	Cryptococcus neoformans	32.31	1.00e-38	156.00
IUUC-Cme-027247	Cyanidioschyzon merolae	25.43	5.00e-11	62.80
IUUC-Dre-028623	Danio rerio	75.62	0.00e+00	1928.00
IUUC-Dno-030044	Dasypus novemcinctus	95.17	0.00e+00	2363.00
IUUC-Dor-030272	Dipodomys ordii	88.14	0.00e+00	2050.00
IUUC-Dme-032099	Drosophila melanogaster	37.18	3.00e-48	187.00
IUUC-Ete-032927	Echinops telfairi	96.83	0.00e+00	1022.00
IUUC-Eca-033469	Equus caballus	95.18	0.00e+00	2322.00
IUUC-Eeu-034977	Erinaceus europaeus	90.88	0.00e+00	1086.00
IUUC-Fca-036419	Felis catus	94.52	0.00e+00	2336.00
IUUC-Fal-037236	Ficedula albicollis	88.91	0.00e+00	2224.00
IUUC-Gmo-039632	Gadus morhua	69.36	0.00e+00	1669.00
IUUC-Gga-040835	Gallus gallus	89.12	0.00e+00	2216.00
IUUC-Gac-041948	Gasterosteus aculeatus	72.55	0.00e+00	1793.00
IUUC-Ggo-045100	Gorilla gorilla	87.15	0.00e+00	1901.00
IUUC-Hsa-045699	Homo sapiens	96.13	0.00e+00	2404.00
IUUC-Hvu-047530	Hordeum vulgare	33.14	1.00e-14	75.10
IUUC-Itr-048773	Ictidomys tridecemlineatus	92.35	0.00e+00	2308.00
IUUC-Kpa-049215	Komagataella pastoris	40.00	5.00e-15	75.90
IUUC-Lch-050094	Latimeria chalumnae	71.39	0.00e+00	1261.00
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Loc-052613	Lepisosteus oculatus	80.02	0.00e+00	1959.00
IUUC-Laf-053608	Loxodonta africana	93.26	0.00e+00	2341.00
IUUC-Mcc-055720	Macaca mulatta	96.43	0.00e+00	2381.00
IUUC-Meu-056445	Macropus eugenii	83.98	0.00e+00	1684.00
IUUC-Mga-059997	Meleagris gallopavo	58.42	0.00e+00	1444.00
IUUC-Mmr-061258	Microcebus murinus	95.65	0.00e+00	2343.00
IUUC-Mdo-062019	Monodelphis domestica	90.76	0.00e+00	2203.00
IUUC-Mmu-063885	Mus musculus	93.28	0.00e+00	2355.00
IUUC-Mac-065649	Musa acuminata	33.06	2.00e-12	68.20
IUUC-Mlu-068190	Myotis lucifugus	64.87	0.00e+00	1299.00
IUUC-Nle-069448	Nomascus leucogenys	86.07	0.00e+00	1199.00
IUUC-Opr-070441	Ochotona princeps	90.66	0.00e+00	2068.00
IUUC-Ont-071752	Oreochromis niloticus	72.57	0.00e+00	1786.00
IUUC-Oan-073390	Ornithorhynchus anatinus	86.51	0.00e+00	2124.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	2.00e-14	74.70
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	2.00e-14	74.70
IUUC-Oni-082167	Oryza nivara	41.67	5.00e-14	73.90
IUUC-Oru-084541	Oryza rufipogon	41.67	4.00e-14	73.90
IUUC-Ola-087489	Oryzias latipes	49.73	0.00e+00	1161.00
IUUC-Olu-087698	Ostreococcus lucimarinus	27.30	3.00e-16	80.10
IUUC-Oga-088602	Otolemur garnettii	96.03	0.00e+00	2357.00
IUUC-Oar-090195	Ovis aries	93.92	0.00e+00	2315.00
IUUC-Ptr-091363	Pan troglodytes	96.21	0.00e+00	2405.00
IUUC-Pan-092385	Papio anubis	96.13	0.00e+00	2382.00
IUUC-Psi-093551	Pelodiscus sinensis	88.08	0.00e+00	1248.00
IUUC-Pfo-097486	Poecilia formosa	73.74	0.00e+00	1825.00
IUUC-Pab-098281	Pongo abelii	84.76	0.00e+00	2020.00
IUUC-Pca-100270	Procavia capensis	78.87	0.00e+00	1316.00
IUUC-Pva-102335	Pteropus vampyrus	91.54	0.00e+00	2290.00
IUUC-Ptt-103973	Puccinia triticina	24.74	4.00e-27	118.00
IUUC-Rno-106122	Rattus norvegicus	93.04	0.00e+00	2336.00
IUUC-Sha-106851	Sarcophilus harrisii	91.00	0.00e+00	2217.00
IUUC-Sit-110414	Setaria italica	40.48	3.00e-14	74.30
IUUC-Sar-112978	Sorex araneus	56.83	0.00e+00	689.00
IUUC-Sbi-114170	Sorghum bicolor	40.00	9.00e-15	75.90
IUUC-Ssc-115562	Sus scrofa	60.20	0.00e+00	1158.00
IUUC-Tgu-117028	Taeniopygia guttata	89.63	0.00e+00	2260.00
IUUC-Tru-117789	Takifugu rubripes	75.23	0.00e+00	1827.00
IUUC-Tsy-119039	Tarsius syrichta	94.31	0.00e+00	1406.00
IUUC-Tni-119952	Tetraodon nigroviridis	73.22	0.00e+00	1701.00
IUUC-Tae-123242	Triticum aestivum	41.67	4.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	41.67	4.00e-14	73.90
IUUC-Tbe-127754	Tupaia belangeri	84.60	0.00e+00	1703.00
IUUC-Ttr-129178	Tursiops truncatus	95.34	0.00e+00	2344.00
IUUC-Vpa-130687	Vicugna pacos	90.04	0.00e+00	1153.00
IUUC-Xtr-132905	Xenopus tropicalis	85.44	0.00e+00	2138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence