iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002428.1	ENSSHAT00000002776.1	ENSSHAP00000002745.1
ENSSHAG00000002428.1	ENSSHAT00000002777.1	ENSSHAP00000002746.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.80e-66	219.5	1160	1212

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+ +ydy+aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+ 
   Q: 1160 QVIGMYDYTAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVKM 1212
           46779**********************..8889******..9*************85 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAQFPTSFGG SLDIWAITVE ERTKHDQQFH SLKPTSGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQIEFSI AMKLIKLKLQ GYQLPATLPP VMKQQPVAIS GAPTFGIGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTCTACTA GCGAGCTAAA AGTGACAGAA CCATGGCTCA ATTTCCGACA TCTTTTGGTG 60
GTAAGTTTTC ACGTTTTTTT CTTTAGCAAG TTGCAAAGTG CATTGACGGA AAGGTCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	3.00e-14	74.70
IUUC-Aml-001218	Ailuropoda melanoleuca	90.96	0.00e+00	2292.00
IUUC-Apl-003335	Anas platyrhynchos	90.74	0.00e+00	2217.00
IUUC-Aca-005130	Anolis carolinensis	88.90	0.00e+00	2195.00
IUUC-Ago-007935	Ashbya gossypii	35.07	2.00e-14	73.90
IUUC-Ame-011878	Astyanax mexicanus	76.20	0.00e+00	1910.00
IUUC-Bta-012863	Bos taurus	90.48	0.00e+00	2256.00
IUUC-Bdi-014016	Brachypodium distachyon	29.53	1.00e-14	75.90
IUUC-Bol-015187	Brassica oleracea	37.66	1.00e-10	61.60
IUUC-Bra-017706	Brassica rapa	35.83	1.00e-12	68.90
IUUC-Cel-018490	Caenorhabditis elegans	33.97	1.00e-43	172.00
IUUC-Cja-019012	Callithrix jacchus	91.44	0.00e+00	2278.00
IUUC-Cfa-020272	Canis familiaris	91.36	0.00e+00	2303.00
IUUC-Cpo-021352	Cavia porcellus	84.73	0.00e+00	2706.00
IUUC-Csa-023122	Chlorocebus sabaeus	65.38	0.00e+00	1282.00
IUUC-Cho-024969	Choloepus hoffmanni	80.28	0.00e+00	1799.00
IUUC-Cin-025435	Ciona intestinalis	45.71	0.00e+00	974.00
IUUC-Csv-026290	Ciona savignyi	58.07	0.00e+00	787.00
IUUC-Cne-026918	Cryptococcus neoformans	33.55	5.00e-39	157.00
IUUC-Dre-028623	Danio rerio	76.00	0.00e+00	1930.00
IUUC-Dno-030044	Dasypus novemcinctus	90.61	0.00e+00	2265.00
IUUC-Dor-030272	Dipodomys ordii	84.32	0.00e+00	1980.00
IUUC-Dme-032099	Drosophila melanogaster	53.46	5.00e-44	173.00
IUUC-Ete-032927	Echinops telfairi	96.39	0.00e+00	1023.00
IUUC-Eca-033469	Equus caballus	91.36	0.00e+00	2262.00
IUUC-Eeu-034977	Erinaceus europaeus	85.74	0.00e+00	1029.00
IUUC-Fca-036419	Felis catus	91.44	0.00e+00	2264.00
IUUC-Fal-037236	Ficedula albicollis	88.28	0.00e+00	2205.00
IUUC-Gmo-039632	Gadus morhua	68.75	0.00e+00	1654.00
IUUC-Gga-040835	Gallus gallus	88.41	0.00e+00	2184.00
IUUC-Gac-041948	Gasterosteus aculeatus	71.31	0.00e+00	1786.00
IUUC-Ggo-045405	Gorilla gorilla	55.84	0.00e+00	1631.00
IUUC-Hsa-045699	Homo sapiens	91.83	0.00e+00	2313.00
IUUC-Hvu-047530	Hordeum vulgare	31.18	4.00e-14	73.20
IUUC-Itr-048773	Ictidomys tridecemlineatus	89.00	0.00e+00	2216.00
IUUC-Lch-050502	Latimeria chalumnae	78.89	0.00e+00	1624.00
IUUC-Lpe-051250	Leersia perrieri	41.67	3.00e-14	74.30
IUUC-Loc-052613	Lepisosteus oculatus	79.30	0.00e+00	1957.00
IUUC-Laf-053608	Loxodonta africana	90.05	0.00e+00	2277.00
IUUC-Mcc-055720	Macaca mulatta	91.28	0.00e+00	2290.00
IUUC-Meu-056445	Macropus eugenii	88.84	0.00e+00	1767.00
IUUC-Mtr-057705	Medicago truncatula	36.27	2.00e-12	68.20
IUUC-Mla-059128	Melampsora laricipopulina	29.91	1.00e-38	156.00
IUUC-Mga-059997	Meleagris gallopavo	58.22	0.00e+00	1438.00
IUUC-Mvi-060268	Microbotryum violaceum	29.40	2.00e-43	171.00
IUUC-Mmr-061258	Microcebus murinus	91.99	0.00e+00	2272.00
IUUC-Mdo-062019	Monodelphis domestica	97.22	0.00e+00	2338.00
IUUC-Mmu-063885	Mus musculus	90.09	0.00e+00	2276.00
IUUC-Mpu-066431	Mustela putorius furo	64.97	0.00e+00	1290.00
IUUC-Mlu-068190	Myotis lucifugus	58.27	0.00e+00	1392.00
IUUC-Nle-070116	Nomascus leucogenys	61.27	0.00e+00	935.00
IUUC-Opr-070441	Ochotona princeps	85.15	0.00e+00	1996.00
IUUC-Ont-071752	Oreochromis niloticus	72.57	0.00e+00	1785.00
IUUC-Oan-073390	Ornithorhynchus anatinus	87.79	0.00e+00	2139.00
IUUC-Ocu-073753	Oryctolagus cuniculus	89.00	0.00e+00	2854.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	3.00e-14	74.30
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	74.70
IUUC-Ome-081199	Oryza meridionalis	41.67	3.00e-14	74.30
IUUC-Oni-082167	Oryza nivara	41.67	5.00e-14	73.60
IUUC-Oru-084541	Oryza rufipogon	41.67	5.00e-14	73.60
IUUC-Ola-086482	Oryzias latipes	55.47	0.00e+00	1108.00
IUUC-Olu-087698	Ostreococcus lucimarinus	28.75	2.00e-17	84.00
IUUC-Oga-088602	Otolemur garnettii	91.83	0.00e+00	2282.00
IUUC-Oar-090195	Ovis aries	90.64	0.00e+00	2264.00
IUUC-Ptr-091363	Pan troglodytes	91.91	0.00e+00	2315.00
IUUC-Pan-092385	Papio anubis	91.70	0.00e+00	2303.00
IUUC-Psi-093136	Pelodiscus sinensis	63.77	0.00e+00	1289.00
IUUC-Pfo-097486	Poecilia formosa	74.29	0.00e+00	1821.00
IUUC-Pab-098281	Pongo abelii	80.98	0.00e+00	1932.00
IUUC-Pca-100270	Procavia capensis	74.47	0.00e+00	1268.00
IUUC-Pva-102335	Pteropus vampyrus	89.06	0.00e+00	2203.00
IUUC-Pgr-103473	Puccinia graminis	28.99	2.00e-36	149.00
IUUC-Ptt-103973	Puccinia triticina	24.01	7.00e-26	114.00
IUUC-Rno-106122	Rattus norvegicus	89.00	0.00e+00	2244.00
IUUC-Sja-107736	Schizosaccharomyces japonicus	26.63	6.00e-18	86.30
IUUC-Smo-108995	Selaginella moellendorffii	36.62	4.00e-08	53.10
IUUC-Sit-110414	Setaria italica	40.48	4.00e-14	73.90
IUUC-Sbi-114170	Sorghum bicolor	38.89	3.00e-14	74.30
IUUC-Sre-115028	Sporisorium reilianum	34.13	6.00e-32	134.00
IUUC-Ssc-115562	Sus scrofa	61.04	0.00e+00	1159.00
IUUC-Tgu-117028	Taeniopygia guttata	89.32	0.00e+00	2236.00
IUUC-Tru-117789	Takifugu rubripes	76.02	0.00e+00	1850.00
IUUC-Tsy-119039	Tarsius syrichta	92.31	0.00e+00	1381.00
IUUC-Tni-119952	Tetraodon nigroviridis	74.26	0.00e+00	1714.00
IUUC-Tae-123242	Triticum aestivum	41.67	4.00e-14	73.60
IUUC-Tur-126623	Triticum urartu	40.00	4.00e-14	73.90
IUUC-Tbe-127754	Tupaia belangeri	79.74	0.00e+00	1598.00
IUUC-Ttr-129178	Tursiops truncatus	90.73	0.00e+00	2259.00
IUUC-Uma-129456	Ustilago maydis	31.01	8.00e-32	133.00
IUUC-Vpa-130687	Vicugna pacos	84.32	0.00e+00	1061.00
IUUC-Xtr-132905	Xenopus tropicalis	86.39	0.00e+00	2158.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence