iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000206530.9	ENST00000489244.1	ENSP00000418257.1
ENSG00000206530.9	ENST00000465636.5	ENSP00000417371.1
ENSG00000206530.9	ENST00000461734.1	ENSP00000418795.1
ENSG00000206530.9	ENST00000490481.1	ENSP00000419269.1
ENSG00000206530.9	ENST00000488854.6	ENSP00000419844.2
ENSG00000206530.9	ENST00000295868.6	ENSP00000295868.2
ENSG00000206530.9	ENST00000465186.1	ENSP00000418743.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	CircNet	microRNA
TRANSFAC	TargetScan	RepTar	SomamiR
miRcode	RAID2
Protein-protein Interaction
InWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	Phospho.ELM
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-18	65.5	366	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           H+++++ + + ++ +++ + Dg +++WD+ t
   Q: 366  HNGPINQIMLYEGEVITVGSDGYVRIWDFET 396
           99******9834889*************876 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MKEPDDQDTD GEKSVTSKSD GKKSLRSSKS ESRSPVQEDN TFLEDDTDET FTKGEGSYLE 60
EDSDEERLEG SLSSFQYGDL QSTTVPQQTP APAVEEAEEE VKKKISESFF YDYMELASMP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTCCCGG AGAGCTGGAC GCCGGCCGCG CATGCGCCCC ACGGCCCGCC CTGGTTCCGC 60
CTCCCTGGAA GAGGGGTGGC GTTGTCTCGG TAACCGGAGT AAACGGAGGC CTCCGGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0042995--C:cell projection
GO:0060285--P:cilium-dependent cell motility

KEGG

hsa:55779

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence