iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	1.50e-15	57.8	255	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 4    eqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++qiRl+dG+rl ++F+s++++ ++++f+   +  +  + F Lv++fP ++l++e+   tlq+a+++++ +l+
   Q: 255  PTTKIQIRLADGSRLIQRFNSTHRILDVRDFIVqSRPEFATTDFILVTSFPSKELTDESV--TLQDADILNTVILQ 328
           589******************************7788889999*****************..*********99985 PP

Organism

Rattus norvegicus

Functional Description
(View)

Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity).

Protein Sequence
(Fasta)

MAEGGGAEPE EQERRSSRPR PPSARDLQLA LAELYEDEMK CKSSKPDRST ATAFKSPRTP 60
PLRLYSGDQE YGGLHIAQPP TGKIVNELFK EAREHGAVPL NEATRSSSDD KAKSFTGGGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGTGTCTT CATAGGAACG TGAAAGCCTA TGTGGGTGTA TCATACTGTT GGCAATCAAG 60
AAAAGTAGCT AAGATGTGGT AAACAGACCT CTCAGATTCA TCTTCTCTAG CTTGTAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

SMART

SM00553--SEP
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0005634--C:nucleus
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

rno:312965

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001637	Ailuropoda melanoleuca	87.61	3.00e-167	580.00
IUUC-Apl-003738	Anas platyrhynchos	72.75	5.00e-124	437.00
IUUC-Aca-005097	Anolis carolinensis	73.70	2.00e-121	428.00
IUUC-Acl-008176	Aspergillus clavatus	39.23	6.00e-30	124.00
IUUC-Afl-008553	Aspergillus flavus	36.46	2.00e-26	112.00
IUUC-Afu-008919	Aspergillus fumigatus	37.57	2.00e-29	123.00
IUUC-Aor-010016	Aspergillus oryzae	36.46	3.00e-26	112.00
IUUC-Bgr-012256	Blumeria graminis	34.47	4.00e-27	115.00
IUUC-Bta-012629	Bos taurus	87.01	6.00e-151	526.00
IUUC-Bci-013750	Botrytis cinerea	32.10	1.00e-28	120.00
IUUC-Bdi-014204	Brachypodium distachyon	32.04	2.00e-33	137.00
IUUC-Cja-019732	Callithrix jacchus	78.85	1.00e-136	479.00
IUUC-Cfa-021132	Canis familiaris	87.01	1.00e-166	578.00
IUUC-Cpo-021389	Cavia porcellus	86.36	6.00e-158	549.00
IUUC-Csa-023362	Chlorocebus sabaeus	87.61	4.00e-166	577.00
IUUC-Cgl-026628	Colletotrichum gloeosporioides	32.58	4.00e-23	102.00
IUUC-Dno-029956	Dasypus novemcinctus	86.79	1.00e-151	528.00
IUUC-Dor-031124	Dipodomys ordii	80.84	8.00e-136	476.00
IUUC-Eca-034063	Equus caballus	87.61	3.00e-166	577.00
IUUC-Fca-035606	Felis catus	86.40	1.00e-164	572.00
IUUC-Fal-036923	Ficedula albicollis	72.29	2.00e-122	432.00
IUUC-Ggr-039971	Gaeumannomyces graminis	29.38	8.00e-15	75.10
IUUC-Gga-040906	Gallus gallus	74.92	1.00e-135	476.00
IUUC-Gma-044296	Glycine max	34.43	6.00e-36	144.00
IUUC-Ggo-044801	Gorilla gorilla	88.96	1.00e-162	565.00
IUUC-Hsa-046853	Homo sapiens	88.96	1.00e-162	565.00
IUUC-Hvu-047203	Hordeum vulgare	33.46	7.00e-31	127.00
IUUC-Itr-047910	Ictidomys tridecemlineatus	91.22	1.00e-141	495.00
IUUC-Lpe-051122	Leersia perrieri	34.17	1.00e-34	140.00
IUUC-Lma-053319	Leptosphaeria maculans	34.34	5.00e-34	138.00
IUUC-Laf-053854	Loxodonta africana	85.44	9.00e-145	506.00
IUUC-Mcc-055607	Macaca mulatta	87.31	1.00e-161	561.00
IUUC-Mpo-057595	Magnaporthe poae	28.09	1.00e-18	87.40
IUUC-Mga-059714	Meleagris gallopavo	74.92	5.00e-135	473.00
IUUC-Mmr-061091	Microcebus murinus	90.58	6.00e-165	573.00
IUUC-Mdo-062985	Monodelphis domestica	83.01	2.00e-139	488.00
IUUC-Mmu-064382	Mus musculus	91.84	2.00e-169	587.00
IUUC-Mpu-066168	Mustela putorius furo	89.61	1.00e-163	568.00
IUUC-Mlu-067562	Myotis lucifugus	83.69	5.00e-150	523.00
IUUC-Nfi-068609	Neosartorya fischeri	38.12	1.00e-29	123.00
IUUC-Ncr-068786	Neurospora crassa	33.87	3.00e-24	106.00
IUUC-Nle-069639	Nomascus leucogenys	89.29	4.00e-163	566.00
IUUC-Oan-073007	Ornithorhynchus anatinus	82.57	4.00e-147	513.00
IUUC-Ocu-074507	Oryctolagus cuniculus	88.52	2.00e-166	577.00
IUUC-Oba-075011	Oryza barthii	33.70	2.00e-33	135.00
IUUC-Obr-076164	Oryza brachyantha	35.68	6.00e-28	117.00
IUUC-Ogl-077805	Oryza glaberrima	33.70	2.00e-33	135.00
IUUC-Ogu-078942	Oryza glumaepatula	33.70	1.00e-33	137.00
IUUC-Oin-079497	Oryza indica	34.07	1.00e-32	134.00
IUUC-Olo-080254	Oryza longistaminata	35.94	8.00e-30	124.00
IUUC-Ome-081766	Oryza meridionalis	34.43	6.00e-32	132.00
IUUC-Oni-082258	Oryza nivara	33.70	2.00e-33	135.00
IUUC-Opu-083365	Oryza punctata	34.06	1.00e-35	143.00
IUUC-Oru-084748	Oryza rufipogon	33.70	1.00e-33	137.00
IUUC-Osa-085359	Oryza sativa	33.70	2.00e-33	135.00
IUUC-Oga-088292	Otolemur garnettii	77.52	5.00e-138	483.00
IUUC-Oar-090236	Ovis aries	85.71	2.00e-146	511.00
IUUC-Ptr-090664	Pan troglodytes	88.96	1.00e-162	565.00
IUUC-Pan-092072	Papio anubis	87.83	3.00e-159	553.00
IUUC-Psi-093486	Pelodiscus sinensis	77.99	2.00e-129	455.00
IUUC-Pno-094769	Phaeosphaeria nodorum	32.16	7.00e-34	138.00
IUUC-Pab-097813	Pongo abelii	88.96	1.00e-162	565.00
IUUC-Pca-100985	Procavia capensis	73.13	3.00e-102	364.00
IUUC-Ppe-101417	Prunus persica	34.30	1.00e-34	140.00
IUUC-Pva-102600	Pteropus vampyrus	88.58	3.00e-162	564.00
IUUC-Pte-104083	Pyrenophora teres	40.61	2.00e-39	156.00
IUUC-Sha-106777	Sarcophilus harrisii	77.99	3.00e-67	248.00
IUUC-Sja-107717	Schizosaccharomyces japonicus	31.70	4.00e-30	125.00
IUUC-Sbi-114513	Sorghum bicolor	33.33	8.00e-35	141.00
IUUC-Sre-115176	Sporisorium reilianum	38.66	3.00e-32	133.00
IUUC-Ssc-115936	Sus scrofa	88.64	3.00e-150	524.00
IUUC-Tgu-116752	Taeniopygia guttata	73.65	1.00e-125	442.00
IUUC-Tsy-119015	Tarsius syrichta	76.95	1.00e-133	469.00
IUUC-Tca-121311	Theobroma cacao	35.51	6.00e-32	130.00
IUUC-Ttr-128760	Tursiops truncatus	88.64	1.00e-151	528.00
IUUC-Vpa-130155	Vicugna pacos	86.47	9.00e-149	519.00
IUUC-Vvi-131338	Vitis vinifera	32.88	1.00e-32	133.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence