iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000222009.8	ENST00000409335.6	ENSP00000386506.2
ENSG00000222009.8	ENST00000439563.2	ENSP00000410162.2
ENSG00000222009.8	ENST00000450269.5	ENSP00000395461.1

Annotation

Cancer Mutation
ICGC	COSMIC	CGAP	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
circBase	CircNet	miRTarBase	microRNA
TRANSFAC	TargetScan	miRcode	RAID2
Protein-protein Interaction
IID	InWeb_IM
Disease-associated Variation
GWASdb	GWAS Central
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.90e-12	49.0	29	95

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvg..geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv++vvg  ++e+fah++ La ++ +F++l+ +e   +   + v+++ v  e+f a+l+FlYt++++
   Q: 29   SDVCFVVGqeRQEVFAHRCLLACRCNFFQRLLGTEPGPGV-PSPVVLSTVPTEAFLAVLEFLYTNSVK 95
           6******999***************************998.88899999***************9986 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MEPLGLVVHG KAEPFSAALR SLVNNPRYSD VCFVVGQERQ EVFAHRCLLA CRCNFFQRLL 60
GTEPGPGVPS PVVLSTVPTE AFLAVLEFLY TNSVKLYRHS VLEVLTAAVE YGLEELRELC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCTTCCCA CCCCGTCGGC TGCCTGGGCA GACTCCCAGC CAGGGCCTCT TTCGCCGCCG 60
CCGCCGCCGC CAGCCAGCCA GCTTCTTCCC AGGACCATAG GCCACTCCAG CCTCAGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB

SMART

SM00875--BACK
SM00225--BTB

KEGG

hsa:149478

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002186	Ailuropoda melanoleuca	89.69	3.00e-109	387.00
IUUC-Aca-004691	Anolis carolinensis	53.96	1.00e-59	223.00
IUUC-Bta-012926	Bos taurus	92.10	4.00e-104	370.00
IUUC-Cja-019258	Callithrix jacchus	93.47	6.00e-123	433.00
IUUC-Cfa-020942	Canis familiaris	79.75	3.00e-94	338.00
IUUC-Cpo-021872	Cavia porcellus	88.66	6.00e-112	397.00
IUUC-Csa-023336	Chlorocebus sabaeus	97.59	9.00e-113	399.00
IUUC-Cin-025194	Ciona intestinalis	34.51	7.00e-41	160.00
IUUC-Dno-029059	Dasypus novemcinctus	85.37	1.00e-60	226.00
IUUC-Eca-034124	Equus caballus	89.35	1.00e-92	332.00
IUUC-Fca-036504	Felis catus	89.69	4.00e-102	364.00
IUUC-Fal-037125	Ficedula albicollis	57.58	4.00e-73	268.00
IUUC-Gga-040882	Gallus gallus	50.79	1.00e-73	269.00
IUUC-Ggo-045037	Gorilla gorilla	98.97	5.00e-104	370.00
IUUC-Itr-048805	Ictidomys tridecemlineatus	91.75	3.00e-116	411.00
IUUC-Laf-054364	Loxodonta africana	89.35	4.00e-113	400.00
IUUC-Mcc-055226	Macaca mulatta	93.27	4.00e-102	364.00
IUUC-Mla-059123	Melampsora laricipopulina	32.00	1.60e-01	31.20
IUUC-Mga-059246	Meleagris gallopavo	57.19	1.00e-81	296.00
IUUC-Mmr-061765	Microcebus murinus	79.38	4.00e-96	343.00
IUUC-Mdo-062797	Monodelphis domestica	61.64	2.00e-40	159.00
IUUC-Mmu-063478	Mus musculus	88.66	7.00e-100	356.00
IUUC-Mpu-066922	Mustela putorius furo	88.32	6.00e-103	367.00
IUUC-Mlu-068138	Myotis lucifugus	79.17	3.00e-77	281.00
IUUC-Nle-070120	Nomascus leucogenys	97.25	2.00e-115	408.00
IUUC-Oan-072785	Ornithorhynchus anatinus	54.79	4.00e-39	154.00
IUUC-Ocu-074847	Oryctolagus cuniculus	88.66	3.00e-100	358.00
IUUC-Oga-088314	Otolemur garnettii	90.03	3.00e-120	424.00
IUUC-Oar-089867	Ovis aries	78.69	2.00e-83	301.00
IUUC-Ptr-091231	Pan troglodytes	98.97	5.00e-115	407.00
IUUC-Pan-092818	Papio anubis	97.94	2.00e-113	402.00
IUUC-Pma-094309	Petromyzon marinus	46.24	4.00e-43	167.00
IUUC-Rno-105669	Rattus norvegicus	87.93	2.00e-111	395.00
IUUC-Sha-107053	Sarcophilus harrisii	56.51	1.00e-63	236.00
IUUC-Smo-108816	Selaginella moellendorffii	30.64	5.00e-08	52.40
IUUC-Ssc-115457	Sus scrofa	91.75	6.00e-115	407.00
IUUC-Tme-126982	Tuber melanosporum	36.05	4.00e-08	53.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence