iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067622

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02028320

Gene Name

BMI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001692.2	ENSMLUT00000001691.2	ENSMLUP00000001553.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.70e-06	27.9	18	57
ULD/UDP/UFD/RAWUL	1.10e-30	106.0	131	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++ +          ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 131  ISLSIEFFDQNRLDRKVNkdkekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
           7899999999998887768888899999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 220  PLPLKYR 226
           ******9 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADATNGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTCAGGC CCCAGCCCCA GGCTGACTCG AGGTGCTTCT CCTGAGGCCC CAGCACCCAG 60
CTCCGGAAAT GCCAGGGATG CAGATCGAGC AGAATTTATT TTCCCTTTGT GTTGGGTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001498	Ailuropoda melanoleuca	98.16	2.00e-169	587.00
IUUC-Apl-004208	Anas platyrhynchos	94.44	2.00e-135	474.00
IUUC-Aca-004661	Anolis carolinensis	82.82	1.00e-138	485.00
IUUC-Ath-007649	Arabidopsis thaliana	42.50	3.00e-12	66.60
IUUC-Ame-010610	Astyanax mexicanus	75.08	4.00e-139	487.00
IUUC-Bta-012606	Bos taurus	98.47	3.00e-170	590.00
IUUC-Cja-019482	Callithrix jacchus	99.68	0.00e+00	627.00
IUUC-Cfa-020482	Canis familiaris	98.16	2.00e-169	587.00
IUUC-Cpo-022061	Cavia porcellus	99.04	2.00e-180	624.00
IUUC-Csa-024102	Chlorocebus sabaeus	99.36	0.00e+00	629.00
IUUC-Cho-025081	Choloepus hoffmanni	81.53	4.00e-112	396.00
IUUC-Cin-025612	Ciona intestinalis	48.60	9.00e-52	197.00
IUUC-Dre-027929	Danio rerio	79.75	6.00e-142	496.00
IUUC-Dno-029797	Dasypus novemcinctus	97.45	0.00e+00	641.00
IUUC-Dor-030256	Dipodomys ordii	95.86	8.00e-168	582.00
IUUC-Dme-031904	Drosophila melanogaster	44.59	1.00e-52	202.00
IUUC-Ete-033148	Echinops telfairi	64.29	2.00e-82	298.00
IUUC-Eca-033318	Equus caballus	98.77	9.00e-171	592.00
IUUC-Eeu-034547	Erinaceus europaeus	85.67	5.00e-149	520.00
IUUC-Fca-035866	Felis catus	98.77	3.00e-170	590.00
IUUC-Fal-036660	Ficedula albicollis	95.40	1.00e-160	558.00
IUUC-Gmo-039341	Gadus morhua	83.08	3.00e-126	444.00
IUUC-Gga-040611	Gallus gallus	94.90	4.00e-165	573.00
IUUC-Gac-041888	Gasterosteus aculeatus	72.19	5.00e-128	450.00
IUUC-Gma-042798	Glycine max	39.02	6.00e-12	65.50
IUUC-Ggo-045027	Gorilla gorilla	99.36	0.00e+00	625.00
IUUC-Hsa-045665	Homo sapiens	99.39	0.00e+00	628.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	98.73	5.00e-178	616.00
IUUC-Lch-049714	Latimeria chalumnae	85.63	3.00e-163	567.00
IUUC-Loc-052161	Lepisosteus oculatus	81.96	2.00e-144	505.00
IUUC-Laf-054108	Loxodonta africana	97.27	5.00e-178	616.00
IUUC-Mcc-055562	Macaca mulatta	99.39	0.00e+00	629.00
IUUC-Meu-056709	Macropus eugenii	97.24	6.00e-173	599.00
IUUC-Mtr-058158	Medicago truncatula	43.42	4.00e-10	57.40
IUUC-Mga-060104	Meleagris gallopavo	91.97	3.00e-119	420.00
IUUC-Mmr-061191	Microcebus murinus	99.39	0.00e+00	629.00
IUUC-Mdo-062711	Monodelphis domestica	93.17	1.00e-153	535.00
IUUC-Mmu-064255	Mus musculus	95.22	7.00e-167	579.00
IUUC-Mac-065443	Musa acuminata	36.90	1.00e-11	63.90
IUUC-Mpu-066466	Mustela putorius furo	97.85	2.00e-169	587.00
IUUC-Nle-069253	Nomascus leucogenys	99.36	0.00e+00	629.00
IUUC-Opr-070511	Ochotona princeps	98.41	2.00e-178	617.00
IUUC-Ont-072177	Oreochromis niloticus	84.23	1.00e-129	456.00
IUUC-Oan-073336	Ornithorhynchus anatinus	96.93	7.00e-171	592.00
IUUC-Ocu-074113	Oryctolagus cuniculus	98.73	9.00e-170	588.00
IUUC-Ola-087057	Oryzias latipes	85.19	9.00e-124	436.00
IUUC-Oga-088346	Otolemur garnettii	99.36	0.00e+00	625.00
IUUC-Oar-089843	Ovis aries	98.47	3.00e-170	590.00
IUUC-Ptr-090486	Pan troglodytes	99.36	0.00e+00	625.00
IUUC-Pan-092667	Papio anubis	99.62	1.00e-159	555.00
IUUC-Psi-093469	Pelodiscus sinensis	94.79	5.00e-172	596.00
IUUC-Pma-094481	Petromyzon marinus	74.04	9.00e-90	322.00
IUUC-Ppa-095526	Physcomitrella patens	42.68	1.00e-09	58.20
IUUC-Pfo-097156	Poecilia formosa	79.73	2.00e-133	468.00
IUUC-Pab-097670	Pongo abelii	99.36	0.00e+00	625.00
IUUC-Pop-099100	Populus trichocarpa	37.65	2.00e-12	67.40
IUUC-Pva-102800	Pteropus vampyrus	99.36	0.00e+00	625.00
IUUC-Rno-105128	Rattus norvegicus	94.59	6.00e-170	589.00
IUUC-Sha-106747	Sarcophilus harrisii	97.24	4.00e-162	563.00
IUUC-Sar-113416	Sorex araneus	98.73	2.00e-179	620.00
IUUC-Ssc-115864	Sus scrofa	99.04	1.00e-180	625.00
IUUC-Tgu-116851	Taeniopygia guttata	94.44	6.00e-136	476.00
IUUC-Tru-117698	Takifugu rubripes	86.18	1.00e-124	439.00
IUUC-Tsy-119590	Tarsius syrichta	99.36	1.00e-180	625.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.85	1.00e-128	452.00
IUUC-Tbe-127790	Tupaia belangeri	99.04	3.00e-180	624.00
IUUC-Ttr-129316	Tursiops truncatus	98.77	1.00e-179	621.00
IUUC-Vpa-130669	Vicugna pacos	99.08	4.00e-171	593.00
IUUC-Vvi-131533	Vitis vinifera	42.25	3.00e-10	59.70
IUUC-Xtr-131912	Xenopus tropicalis	87.46	2.00e-147	514.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence