iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098111

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Autophagy-related protein 16-1

Genbank Nucleotide ID

ABGA01402508

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000013289.2	ENSPPYT00000015453.2	ENSPPYP00000014856.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-31	107.3	423	462
UBD/Beta-Prp	4.30e-64	216.6	332	623

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 423  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 462
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
            +++++h++ +++v+fsp+++llatg++d+++k+w+v+ +k+    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   ht
   Q: 332  LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCefKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHT 420
           57899************************************9999******************************************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           l+gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+++  
   Q: 421  LTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME-- 503
           *****************************************9999988....888888889*************************6.. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
             ++++ l+++++++el+s+s+d  +k+ dl+t+ + +t+ +      +  ++v fsp++ +++ gs++gs++iW + +g++ k+l+++
   Q: 504  LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGfkcgSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQ 592
           69**********************************99999988888877777************************************ PP
   S: 264  nssvisvavlsfgdnvlvlgsedskvniwkl 294
           +ss+i   ++s+++ ++v++++ +k+ +w++
   Q: 593  HSSSINAVAWSPSGLHVVSVDKGCKAVLWAQ 623
           *****************************85 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK 60
HDVPNRHEIS PGHDGTWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCACCGG CCCCTGAGCC CGTGCGGCGA AATACGTCGG GTGAGGGGGA GGGTCTTCCG 60
GCCCTCTCGA AAATCATTTC CGGCATGAGC CGGAAGACCG TCCTGGATGG CCTTGGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	29.41	5.00e-33	135.00
IUUC-Aml-002242	Ailuropoda melanoleuca	84.39	0.00e+00	1029.00
IUUC-Apl-003384	Anas platyrhynchos	85.02	0.00e+00	1044.00
IUUC-Aca-004962	Anolis carolinensis	86.22	0.00e+00	1059.00
IUUC-Aly-005435	Arabidopsis lyrata	34.77	3.00e-45	176.00
IUUC-Ath-006948	Arabidopsis thaliana	35.10	8.00e-46	177.00
IUUC-Ame-010915	Astyanax mexicanus	78.77	8.00e-152	529.00
IUUC-Bta-012388	Bos taurus	94.07	0.00e+00	1165.00
IUUC-Bdi-014231	Brachypodium distachyon	30.12	2.00e-37	149.00
IUUC-Bol-016174	Brassica oleracea	35.43	1.00e-45	177.00
IUUC-Bra-017165	Brassica rapa	34.77	5.00e-45	175.00
IUUC-Cel-018131	Caenorhabditis elegans	39.33	3.00e-58	219.00
IUUC-Cja-018898	Callithrix jacchus	85.24	0.00e+00	1002.00
IUUC-Cfa-020484	Canis familiaris	92.79	0.00e+00	1144.00
IUUC-Cpo-022156	Cavia porcellus	92.12	0.00e+00	1125.00
IUUC-Csa-024019	Chlorocebus sabaeus	93.11	0.00e+00	1135.00
IUUC-Cho-024311	Choloepus hoffmanni	79.49	0.00e+00	958.00
IUUC-Cin-025260	Ciona intestinalis	36.95	2.00e-100	359.00
IUUC-Csv-025836	Ciona savignyi	43.96	1.00e-46	179.00
IUUC-Dre-027702	Danio rerio	74.02	0.00e+00	884.00
IUUC-Dno-029728	Dasypus novemcinctus	93.59	0.00e+00	1184.00
IUUC-Dor-030587	Dipodomys ordii	82.78	2.00e-123	436.00
IUUC-Dme-031595	Drosophila melanogaster	37.42	2.00e-105	376.00
IUUC-Ete-032969	Echinops telfairi	73.03	0.00e+00	761.00
IUUC-Eca-034214	Equus caballus	92.14	0.00e+00	935.00
IUUC-Eeu-034537	Erinaceus europaeus	85.56	0.00e+00	887.00
IUUC-Fca-036005	Felis catus	94.26	0.00e+00	1096.00
IUUC-Fal-037593	Ficedula albicollis	86.99	0.00e+00	1018.00
IUUC-Gmo-039042	Gadus morhua	62.91	0.00e+00	663.00
IUUC-Gga-040986	Gallus gallus	86.38	0.00e+00	1078.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.06	0.00e+00	889.00
IUUC-Gma-043452	Glycine max	33.77	9.00e-46	177.00
IUUC-Ggo-045427	Gorilla gorilla	99.68	0.00e+00	1206.00
IUUC-Hsa-046632	Homo sapiens	96.79	0.00e+00	1188.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	90.56	0.00e+00	1102.00
IUUC-Lpe-051254	Leersia perrieri	30.42	2.00e-37	150.00
IUUC-Loc-052610	Lepisosteus oculatus	75.52	0.00e+00	922.00
IUUC-Laf-053936	Loxodonta africana	93.27	0.00e+00	1134.00
IUUC-Mcc-055504	Macaca mulatta	95.22	0.00e+00	1207.00
IUUC-Meu-056516	Macropus eugenii	84.94	0.00e+00	1016.00
IUUC-Mtr-058062	Medicago truncatula	31.68	3.00e-42	166.00
IUUC-Mga-059777	Meleagris gallopavo	82.01	0.00e+00	1031.00
IUUC-Mmr-061298	Microcebus murinus	97.76	0.00e+00	1184.00
IUUC-Mdo-062969	Monodelphis domestica	89.26	0.00e+00	1097.00
IUUC-Mmu-064076	Mus musculus	94.54	0.00e+00	1139.00
IUUC-Mac-065022	Musa acuminata	32.67	6.00e-41	160.00
IUUC-Mpu-066196	Mustela putorius furo	95.19	0.00e+00	1156.00
IUUC-Mlu-067651	Myotis lucifugus	90.72	0.00e+00	1119.00
IUUC-Nle-069853	Nomascus leucogenys	95.03	0.00e+00	1165.00
IUUC-Opr-070350	Ochotona princeps	93.62	9.00e-120	424.00
IUUC-Ont-072489	Oreochromis niloticus	73.16	0.00e+00	878.00
IUUC-Oan-072703	Ornithorhynchus anatinus	83.81	0.00e+00	989.00
IUUC-Ocu-074205	Oryctolagus cuniculus	94.54	0.00e+00	1169.00
IUUC-Oba-075619	Oryza barthii	30.53	3.00e-36	146.00
IUUC-Obr-076632	Oryza brachyantha	29.47	4.00e-37	149.00
IUUC-Ogl-077671	Oryza glaberrima	30.53	3.00e-36	146.00
IUUC-Ogu-078052	Oryza glumaepatula	30.53	3.00e-36	145.00
IUUC-Oin-079611	Oryza indica	30.18	4.00e-34	139.00
IUUC-Olo-080408	Oryza longistaminata	30.53	5.00e-36	145.00
IUUC-Ome-081560	Oryza meridionalis	30.53	3.00e-36	146.00
IUUC-Oni-082145	Oryza nivara	30.53	3.00e-36	146.00
IUUC-Opu-083918	Oryza punctata	30.18	1.00e-35	144.00
IUUC-Oru-084858	Oryza rufipogon	30.18	5.00e-34	138.00
IUUC-Osa-086277	Oryza sativa	30.18	4.00e-34	139.00
IUUC-Ola-086816	Oryzias latipes	68.75	3.00e-97	347.00
IUUC-Olu-087622	Ostreococcus lucimarinus	33.44	4.00e-44	171.00
IUUC-Oga-088765	Otolemur garnettii	89.60	0.00e+00	1055.00
IUUC-Oar-090196	Ovis aries	90.99	0.00e+00	1016.00
IUUC-Ptr-091676	Pan troglodytes	96.96	0.00e+00	1190.00
IUUC-Pan-092068	Papio anubis	99.04	0.00e+00	1198.00
IUUC-Psi-093367	Pelodiscus sinensis	84.29	0.00e+00	1029.00
IUUC-Ppa-095699	Physcomitrella patens	33.44	7.00e-41	161.00
IUUC-Pfo-096067	Poecilia formosa	71.19	0.00e+00	858.00
IUUC-Pop-099116	Populus trichocarpa	31.79	8.00e-42	164.00
IUUC-Pca-100680	Procavia capensis	85.33	0.00e+00	956.00
IUUC-Ppe-101790	Prunus persica	31.79	7.00e-44	171.00
IUUC-Pva-102871	Pteropus vampyrus	92.66	0.00e+00	1072.00
IUUC-Rno-106088	Rattus norvegicus	94.38	0.00e+00	1137.00
IUUC-Sha-106984	Sarcophilus harrisii	87.37	0.00e+00	1060.00
IUUC-Smo-109404	Selaginella moellendorffii	31.45	2.00e-41	163.00
IUUC-Sit-110828	Setaria italica	32.20	3.00e-40	159.00
IUUC-Sly-111009	Solanum lycopersicum	32.01	3.00e-44	172.00
IUUC-Stu-112370	Solanum tuberosum	32.01	8.00e-45	174.00
IUUC-Sar-113659	Sorex araneus	60.38	1.00e-89	322.00
IUUC-Sbi-114819	Sorghum bicolor	31.96	1.00e-38	154.00
IUUC-Ssc-116241	Sus scrofa	89.56	0.00e+00	1097.00
IUUC-Tgu-116576	Taeniopygia guttata	84.94	0.00e+00	1074.00
IUUC-Tru-118336	Takifugu rubripes	64.54	0.00e+00	726.00
IUUC-Tsy-119006	Tarsius syrichta	92.63	0.00e+00	1115.00
IUUC-Tni-120300	Tetraodon nigroviridis	72.06	0.00e+00	853.00
IUUC-Tca-121002	Theobroma cacao	33.90	9.00e-45	174.00
IUUC-Tae-124868	Triticum aestivum	30.10	7.00e-34	138.00
IUUC-Tur-126463	Triticum urartu	29.41	2.00e-33	137.00
IUUC-Tbe-127631	Tupaia belangeri	93.72	0.00e+00	920.00
IUUC-Ttr-129005	Tursiops truncatus	84.52	3.00e-163	568.00
IUUC-Vpa-130246	Vicugna pacos	86.37	0.00e+00	865.00
IUUC-Vvi-130878	Vitis vinifera	34.08	3.00e-43	169.00
IUUC-Xtr-132798	Xenopus tropicalis	72.22	0.00e+00	856.00
IUUC-Xma-133264	Xiphophorus maculatus	70.87	0.00e+00	854.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence