iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
circRNADb	CircNet	miRTarBase	microRNA
TRANSFAC	TargetScan
Protein-protein Interaction
IID	iRefIndex	Mentha
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-08	36.5	2980	3011

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gHt  vtcla   +  llvsGs D+t+ +WDl
   Q: 2980 GHTQAVTCLAAsVTfSLLVSGSQDCTCILWDL 3011
           8*******977644579**************8 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MEAEDLSKAE DRNEDPGSKN EGQLAAVQPD VPHGGQSSSP TALWDMLERK FLEYQQLTHK 60
SPIERQKSLL SLLPLFLKAW EHSVGIICFP SLQRLAEDVS DQLAQQLQKA LVGKPAEQAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCAG AAGATCTTTC AAAGGCTGAA GACAGAAATG AAGACCCAGG TTCCAAAAAT 60
GAAGGGCAGC TTGCTGCTGT GCAGCCTGAT GTCCCACATG GAGGGCAGTC CTCCAGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000409--BEACH_dom
IPR013320--ConA-like_dom
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF02138--Beach
PF00400--WD40

SMART

SM01026--Beach
SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane

KEGG

hsa:57705

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011105	Astyanax mexicanus	41.39	0.00e+00	1168.00
IUUC-Bta-013119	Bos taurus	84.63	0.00e+00	5197.00
IUUC-Cja-019166	Callithrix jacchus	93.38	0.00e+00	5780.00
IUUC-Cfa-021196	Canis familiaris	84.09	0.00e+00	5245.00
IUUC-Cpo-021853	Cavia porcellus	81.79	0.00e+00	2952.00
IUUC-Cho-024719	Choloepus hoffmanni	68.05	0.00e+00	782.00
IUUC-Dre-028733	Danio rerio	42.74	0.00e+00	2393.00
IUUC-Dno-028965	Dasypus novemcinctus	79.45	0.00e+00	4725.00
IUUC-Dor-030745	Dipodomys ordii	73.10	0.00e+00	1124.00
IUUC-Ete-032877	Echinops telfairi	69.12	0.00e+00	1692.00
IUUC-Eca-034106	Equus caballus	86.55	0.00e+00	3169.00
IUUC-Fca-036341	Felis catus	84.24	0.00e+00	3740.00
IUUC-Fal-036739	Ficedula albicollis	52.88	0.00e+00	2996.00
IUUC-Gga-041220	Gallus gallus	58.47	0.00e+00	3519.00
IUUC-Gac-041289	Gasterosteus aculeatus	39.22	0.00e+00	2027.00
IUUC-Ggo-045630	Gorilla gorilla	98.87	0.00e+00	6135.00
IUUC-Itr-048709	Ictidomys tridecemlineatus	84.45	0.00e+00	5209.00
IUUC-Lch-049803	Latimeria chalumnae	52.09	0.00e+00	1792.00
IUUC-Loc-052606	Lepisosteus oculatus	45.36	0.00e+00	2498.00
IUUC-Mcc-055003	Macaca mulatta	96.45	0.00e+00	6017.00
IUUC-Mmr-060933	Microcebus murinus	86.69	0.00e+00	5361.00
IUUC-Mdo-061823	Monodelphis domestica	70.17	0.00e+00	2535.00
IUUC-Mmu-064029	Mus musculus	80.60	0.00e+00	4990.00
IUUC-Mpu-065681	Mustela putorius furo	84.49	0.00e+00	5219.00
IUUC-Nle-069676	Nomascus leucogenys	97.55	0.00e+00	6074.00
IUUC-Ont-072509	Oreochromis niloticus	41.70	0.00e+00	2161.00
IUUC-Ocu-074714	Oryctolagus cuniculus	83.13	0.00e+00	5162.00
IUUC-Ola-087135	Oryzias latipes	38.47	0.00e+00	1947.00
IUUC-Oga-087927	Otolemur garnettii	84.66	0.00e+00	5219.00
IUUC-Oar-089783	Ovis aries	84.16	0.00e+00	5126.00
IUUC-Pan-092402	Papio anubis	96.29	0.00e+00	5997.00
IUUC-Psi-093913	Pelodiscus sinensis	56.50	0.00e+00	3254.00
IUUC-Pfo-096036	Poecilia formosa	40.70	0.00e+00	2123.00
IUUC-Pab-097718	Pongo abelii	93.32	0.00e+00	2540.00
IUUC-Pva-102690	Pteropus vampyrus	86.20	0.00e+00	2509.00
IUUC-Ptt-103873	Puccinia triticina	36.03	9.00e-96	347.00
IUUC-Rno-105815	Rattus norvegicus	80.24	0.00e+00	4982.00
IUUC-Sha-107025	Sarcophilus harrisii	68.20	0.00e+00	4253.00
IUUC-Ssc-115874	Sus scrofa	76.15	0.00e+00	3117.00
IUUC-Tru-118108	Takifugu rubripes	39.33	0.00e+00	1973.00
IUUC-Tsy-118938	Tarsius syrichta	73.13	0.00e+00	1374.00
IUUC-Tbe-127325	Tupaia belangeri	77.38	0.00e+00	1612.00
IUUC-Ttr-128788	Tursiops truncatus	81.93	0.00e+00	2944.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence