iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086390

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04071294

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000012219.1	ENSORLT00000015298.1	ENSORLP00000015297.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.20e-69	233.5	627	951

Active Site

Position(s)	Description	Evidence
923	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++d kk+l v f ++ + d     ++f++++++e+ +p++g+f+++++++  ++p++++      + + F ++G+l+g+al+++ ++ l
   Q: 627  QEDYKKSLVVIFDDNPVFDE-VYIKDFFYEVFHEIVSPEYGMFMFNDSKTLAWFPSKAQQ-----EDQRFFLFGVLCGLALYNQVIIFL 709
           68999**************9.999*********************************996.....44666688**************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           p++ +++k+llg+  sledl e+ p  yk+l  i+    +d   ++l + f+  + + l+e ++++   +  + + + +N++e+v+++v
   Q: 710  PFPLVLFKKLLGVTPSLEDLREFSPSEYKTLHCILYE-YTDDVLENLFIDFQkFTMNDLSELEAKHVTRNLLRRHKNTQNRKEFVDAYV 797
           ******************************9999955.445555567777775567779999999999999999999************ PP
   S: 179  eyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqF 267
           +y +++++k+ +++f +Gf +v++ el++lF++eel   + G++  ++e+lk++t y+ggy++++  i +Fwev+ e+s++++ af+ F
   Q: 798  NYAFNTSVKRIFQEFARGFFKVCDRELVKLFRPEELHRALVGNDFHEWEKLKQNTLYDGGYNPSHTNILMFWEVFDELSENQKMAFVWF 886
           ***************************************************************************************** PP
   S: 268  vTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkg 332
           vTg +rlP+  ++++  +   i++d  d+ +P+s+TCf +L LP Ysskei+ ekL  A ++++ 
   Q: 887  VTGYERLPISALEKITISTKKISEDFGDRYYPESETCFRLLVLPLYSSKEIMTEKLVEALSSNRK 951
           ****************99999999***********************************998765 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

EKIEAVGCGD DEVILLSEKG SVYRVDVTQA LYLPRPVASK LCAKTDRNFV LIFQQIPVSQ 60
VACGSRHTVA LTKEGQVYTW GQNSRGQLGL GKKGCSISSP QCVRSLSGMP LVQVSAGGDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAGATTG AAGCAGTGGG CTGTGGAGAT GATGAGGTCA TTCTGCTCTC TGAGAAGGGC 60
TCAGTTTACC GCGTTGACGT CACTCAAGCT CTTTACCTGC CCAGGTGAGG AGAATCCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gac-042341	Gasterosteus aculeatus	51.95	0.00e+00	872.00
IUUC-Ont-072212	Oreochromis niloticus	56.64	0.00e+00	930.00
IUUC-Pfo-096260	Poecilia formosa	57.08	0.00e+00	984.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence