iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021750

Ensembl Protein ID

ENSCPOP00000004960.2

UniProt Accession

H0V5M5; H0V5M5_CAVPO

Genbank Protein ID

ENSCPOP00000004960

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02016538

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005507.3	ENSCPOT00000005566.2	ENSCPOP00000004960.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-19	69.8	114	146
UBD/Beta-Prp	9.50e-41	139.9	185	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgv 34
           H+ +v+c++   s  ++vsGs+D t kvW+l +g 
   Q: 114  HEQEVNCVDCkgS--IIVSGSRDRTAKVWSLASGQ 146
           99*******9544..9**************99885 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sDg 244
           +r+Wdl++g+l+ +l ++  +    l++ +++   l+s+++d+++++wdl+  t +cv+++++ h+++ ++++++  +++l++gs   g
   Q: 185  LRIWDLNSGQLMSHLGSDFPPGAGVLDVMYESpSTLLSCGYDTYIRYWDLRtsTRKCVMEWEEpHDSTLYCLQTD-GNHLLATGSsYYG 272
           79*************99999999****99999789****************9999*******999**********.999999999789* PP
   S: 245  siriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++r+Wd r++ +l+++ l+    +++v +l+f+  +l+++ +  +++++++k
   Q: 273  VVRLWDQRQRACLHAFPLTStPLSSPVYCLRFTTTHLYAALS-YNLHVLDFK 323
           ******************99667889********99998866.467777776 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MNSVPVKERV KVSQNWRLGR CREGILLKWR CSQMPWMQLE DNSLYISQAN FILAYQFRPD 60
GASLNHRPLG VFAGHDEDVC HFVLANSHIV SAGGDGKIGV HKIHSTFAVK FSAHEQEVNC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACAGTG TCCCGGTGAA GGAGCGGGTG AAGGTGTCTC AGAACTGGAG GCTGGGGCGC 60
TGCCGAGAGG GGATTCTGCT GAAGTGGCGT TGCAGGTGAG CAGAGACTGA CTCTTTCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	93.85	0.00e+00	645.00
IUUC-Apl-003837	Anas platyrhynchos	72.67	1.00e-142	498.00
IUUC-Aca-004776	Anolis carolinensis	69.25	9.00e-122	429.00
IUUC-Ame-010651	Astyanax mexicanus	63.66	8.00e-117	413.00
IUUC-Bta-013495	Bos taurus	93.23	1.00e-176	612.00
IUUC-Cja-018901	Callithrix jacchus	94.15	2.00e-178	618.00
IUUC-Cfa-021251	Canis familiaris	93.23	0.00e+00	641.00
IUUC-Csa-024026	Chlorocebus sabaeus	94.46	0.00e+00	650.00
IUUC-Cho-024496	Choloepus hoffmanni	70.15	2.00e-128	451.00
IUUC-Cin-025142	Ciona intestinalis	30.85	3.00e-16	78.60
IUUC-Csv-025883	Ciona savignyi	38.39	7.00e-63	234.00
IUUC-Dre-027447	Danio rerio	61.61	4.00e-116	411.00
IUUC-Dno-029572	Dasypus novemcinctus	83.59	4.00e-160	558.00
IUUC-Dor-030982	Dipodomys ordii	93.84	3.00e-167	581.00
IUUC-Dme-031804	Drosophila melanogaster	22.39	2.00e-10	59.70
IUUC-Ete-032917	Echinops telfairi	91.08	0.00e+00	631.00
IUUC-Eca-033969	Equus caballus	93.54	1.00e-176	612.00
IUUC-Eeu-034850	Erinaceus europaeus	83.08	5.00e-161	560.00
IUUC-Fca-036182	Felis catus	93.85	0.00e+00	645.00
IUUC-Fal-037391	Ficedula albicollis	72.10	3.00e-137	481.00
IUUC-Gmo-038632	Gadus morhua	58.57	3.00e-111	394.00
IUUC-Gga-040783	Gallus gallus	73.98	5.00e-144	503.00
IUUC-Gac-042314	Gasterosteus aculeatus	57.23	5.00e-93	334.00
IUUC-Ggo-044739	Gorilla gorilla	94.77	0.00e+00	649.00
IUUC-Hsa-046705	Homo sapiens	94.46	1.00e-178	618.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	94.46	6.00e-166	576.00
IUUC-Loc-052397	Lepisosteus oculatus	68.32	2.00e-127	448.00
IUUC-Laf-054544	Loxodonta africana	92.97	0.00e+00	639.00
IUUC-Meu-056363	Macropus eugenii	59.38	2.00e-103	368.00
IUUC-Mga-059275	Meleagris gallopavo	73.98	3.00e-144	504.00
IUUC-Mmr-060906	Microcebus murinus	93.85	0.00e+00	646.00
IUUC-Mdo-062400	Monodelphis domestica	78.46	1.00e-156	545.00
IUUC-Mmu-063556	Mus musculus	91.08	0.00e+00	626.00
IUUC-Mpu-066500	Mustela putorius furo	93.85	0.00e+00	645.00
IUUC-Mlu-068074	Myotis lucifugus	93.85	0.00e+00	645.00
IUUC-Nle-069601	Nomascus leucogenys	94.77	0.00e+00	649.00
IUUC-Opr-070904	Ochotona princeps	83.12	1.00e-117	416.00
IUUC-Ont-072679	Oreochromis niloticus	56.39	2.00e-108	385.00
IUUC-Oan-073434	Ornithorhynchus anatinus	72.09	5.00e-66	243.00
IUUC-Ocu-074649	Oryctolagus cuniculus	93.85	0.00e+00	650.00
IUUC-Ola-087336	Oryzias latipes	50.16	3.00e-87	315.00
IUUC-Oga-088590	Otolemur garnettii	92.00	3.00e-175	607.00
IUUC-Oar-090178	Ovis aries	93.54	5.00e-176	610.00
IUUC-Pan-092881	Papio anubis	94.15	0.00e+00	647.00
IUUC-Pfo-096176	Poecilia formosa	56.21	3.00e-96	345.00
IUUC-Pab-098285	Pongo abelii	94.77	0.00e+00	649.00
IUUC-Pca-100888	Procavia capensis	87.38	3.00e-167	581.00
IUUC-Pva-102184	Pteropus vampyrus	78.15	1.00e-147	515.00
IUUC-Rno-105668	Rattus norvegicus	91.38	0.00e+00	631.00
IUUC-Sha-106629	Sarcophilus harrisii	78.57	5.00e-156	543.00
IUUC-Ssc-116183	Sus scrofa	94.77	0.00e+00	651.00
IUUC-Tgu-116630	Taeniopygia guttata	72.41	1.00e-141	496.00
IUUC-Tru-118761	Takifugu rubripes	53.29	1.00e-99	356.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.48	2.00e-60	224.00
IUUC-Ttr-128582	Tursiops truncatus	92.00	2.00e-172	598.00
IUUC-Vpa-130431	Vicugna pacos	73.16	1.00e-93	336.00
IUUC-Xtr-132655	Xenopus tropicalis	67.08	4.00e-129	454.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence